Clinical trials: sponsored by Asan Medical Center
Metastatic Renal Cell Carcinoma
Trial Of Sunitinib In Advanced Non-Clear Cell Type Renal Cell Carcinoma
To evaluate the efficacy and safety of sunitinib in non-clear cell type renal cell carcinoma with the exception of pure sarcomatoid carcinoma and collecting duct carcinoma
- Trial name
- NCT01219751
- Testing
- Sunitinib
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Asan Medical Center
Atazanavir
Two Clinical Trials to Evaluate Pharmacokinetics of Unboosted and Boosted Atazanavir Used Alone or Co-administered With Tenofovir DF in Healthy Korean and Caucasian Male Volunteers
Compared to those of Caucasians, the plasma levels of atazanavir (ATV) may be higher in Koreans with the same dosage regimen(s).
- Trial name
- NCT01368783
- Testing
- atazanavir, Atazanavir(ATZ) and Tenofovir(TDF), Atazanavir(ATZ) + Ritonavir
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Cholecystitis
Prospective Trial for Endoscopic Ultrasound Guided Gallbladder Drainage for Acute Cholecystitis in High Risk Patients
The investigators would like to conduct a prospective, randomized non-inferiority study to compare clinical outcome between endoscopic ultrasound (EUS) guided gallbladder drainage and percutaneous transhepatic gallbladder…
- Trial name
- NCT01146743
- Testing
- EUS-guided gallbladder drainage, percutaneous transhepatic gallbladder drainage
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Asan Medical Center
Healthy Volunteers, Erectile Dysfunction
Phase I Study to Investigate the Alcohol Interaction of DA8159
This study is designed to to investigate the effects of alcohol on the pharmacokinetics of Udenafil tablet in healthy male volunteers
- Trial name
- DA8159_DIA_I (NCT01241032)
- Testing
- Udenafil, Alcohol
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Healthy
Evaluation of Pharmacokinetic and Pharmacodynamic Characteristics of Indobufen, an Anticoagulant Agent
This study is designed to evaluate the pharmacokinetic and pharmacodynamic characteristics of indobufen in healthy subjects.
- Trial name
- NCT01232023
- Testing
- Indobufen
- Where
- 2 sites in South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Healthy
Clinical Trial to Compare the Pharmacokinetics and Pharmacodynamics After Oral Administration of Glucophage and HL-018
This study is designed to to compare the pharmacokinetic and pharmacodynamic characteristics and safety after oral administration of Glucophage with those after oral administration of HL-018 in healthy male volunteers
- Trial name
- NCT01232036
- Testing
- Glucophage 500mg, HL-018 500mg, No administration of Drug
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Renal Insufficiency, Kidney Diseases
Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients
This study is designed to assess the effect of renal impairment on the pharmacokinetics, safety and tolerability of udenafil in subjects with renal impairment compared to healthy subjects.
- Conditions
- Renal Insufficiency, Kidney Diseases, Urologic Diseases
- Trial name
- DA8159_RI_I (NCT01231997)
- Testing
- Udenafil
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Bile Duct Disease
Newly Designed Fully Covered Metal Stent for the Benign Biliary Stricture
The purpose of this study is to determine the feasibility, easy removability, safety, and migration rate of flared end fully covered self-expanding metal stent (FCSEMS) and anchoring FCSEMS for benign biliary stricture.
- Trial name
- NCT00945516
- Testing
- Bona stent® (Flared end FCSEMS), Hanarostent® (Anchoring FCSEMS)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Neutropenia, Hematopoietic Stem Cell Transplantation
Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation
This study is to evaluate safety and prophylaxis effect of micafungin after hematopoietic stem cell transplantation. Micafungin is administered until confirmation of neutrophil engraftment or treatment failure.
- Conditions
- Neutropenia, Hematopoietic Stem Cell Transplantation, Invasive Fungal Disease
- Trial name
- NCT01135589
- Testing
- Micafungin
- Where
- 7 sites in South Korea
- Volunteers
- 145 people
- Sponsor
- Asan Medical Center
Prostatic Neoplasms, Prostatectomy
Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
To date, there is a lack of consensus concerning the optimal timing for removal of the urethral catheter, its related complications, the effectiveness in prophylactic drug use to reduce complication, and the patient reported…
- Trial name
- NCT01209988
- Testing
- tamsulosin 0.4mg, No medication
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Asan Medical Center
Patency, Hepatic Venous Congestion
Usability of Ringed Polytetrafluoroethylene Graft for Venous Vascular Reconstruction of Living Donor Liver Transplantation
Middle hepatic vein (MHV) reconstruction with an interposition vessel graft has been settled as a standard procedure for living donor liver transplantation (LDLT) using a right lobe graft.
- Trial name
- MHVLDLT (NCT01205802)
- Testing
- MHV reconstruction
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Rectal Cancer
Comparison of Preoperative and Postoperative Radiotherapy and Capecitabine in Locally Advanced Rectal Cancer
Based on the potential advantaged of preoperative chemoradiotherapy and oral fluoropyrimidine, the investigators planned a prospective randomized phase III trial which compares preoperative chemoradiotherapy and postoperative…
- Trial name
- NCT01186081
- Testing
- Preoperative chemoradiotherapy, Postoperative chemoradiotherapy
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Asan Medical Center
Lung Cancer
The Role of Narrow Band Imaging Videobronchoscopy in Lung Cancer
Narrow band imaging (NBI) videobronchoscopy is an optical technique in which filtered light enhances superficial neoplasm based on their neoangiogenic pattern.
- Trial name
- NBI (NCT01178190)
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Asan Medical Center
Non-small Cell Lung Cancer
FDG-PET Scan Response Guided Chemotherapy Strategy for Advanced Non-small Cell Lung Cancer
The usual response to chemotherapy is decided through the image change by computed tomography (CT), which is taken at least 6-9 weeks.
- Trial name
- NCT01170923
- Testing
- FDR-PET, CT
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Acute Hypoxemic Respiratory Failure
Comparison Between High-flow Nasal Cannula System and Non-invasive Ventilation in Acute Hypoxemic Respiratory Failure
Acute hypoxemic respiratory failure may require invasive mechanical ventilation. However, invasive mechanical ventilation is associated with a variety of complications.
- Trial name
- NCT01166256
- Testing
- Non-invasive ventilation, High flow nasal cannula system
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Asan Medical Center
Bile Duct Obstruction
Paclitaxel Eluting Covered Metallic Stent for Unresectable Malignant Bile Duct Obstruction
The primary goal is to determine stent patency and overall survival of the conventional covered self expandable metallic stent versus paclitaxel eluting covered self expandable metallic stent in unresectable malignant bile duct…
- Trial name
- NCT00453076
- Testing
- Paclitaxel eluting covered metal stent and control covered metal stent
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Stroke
Reperfusion Therapy in Acute Ischemic Stroke With Unclear Onset
This study will test the hypothesis whether patients with unclear-onset stroke (UnCLOS) treated with thrombolysis could achieve a prespecified rate of good clinical outcome.
- Trial name
- RESTORE (NCT01138059)
- Volunteers
- 83 people
- Sponsor
- Asan Medical Center
Renal Transplant
Latent Tuberculosis Infection in Renal Transplant Recipients
The aim of this study is to estimate the usefulness of a T cell-based assay (i.e. T-SPOT.TB assay) for diagnosis of latent tuberculosis infection (LTBI) in renal transplant recipients.
- Trial name
- NCT00682045
- Where
- South Korea
- Volunteers
- 240 people
- Sponsor
- Asan Medical Center
Ventilator Weaning, Alkalosis, Metabolic
Acetazolamide Facilitates Ventilator Weaning
Metabolic alkalosis(MA) is common metabolic disorder in ICU setting. MA could be cause of weaning failure or delay by depression of respiratory center.
- Trial name
- NCT01131377
- Testing
- acetazolamide, Saline
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Asan Medical Center
Healthy
Bioequivalence Study of Anastrozole 1 mg Tablet
The purpose of this study is to characterize and compare the bioequivalence of CJ anastrozole [CJ Cheiljedang corp., Seoul, Korea] with Arimidex® [AstraZeneca, Wilmington, DE, USA].
- Trial name
- NCT01105299
- Testing
- CJ anastrozole 1 mg tablet
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center