Clinical trials: sponsored by Asan Medical Center
Hair Diseases
Local Anesthesia and Electronic Injector
Local anesthesia-related pain is associated with injection speed. An electronic constant-speed injector was developed for slow and steady injection to alleviate dermatological anesthesia pain.
- Trial name
- NCT06395545
- Testing
- Electronic injector
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Asan Medical Center
Acute Kidney Injury, Chronic Kidney Diseases
Neohepatic Albumin-Bilirubin Scores on Renal Outcomes in Living-donor Liver Transplantation Recipients
This study investigates the association between post-reperfusion (neohepatic) ALBI scores and post-LT renal outcomes in living-donor LT (LDLT) recipients.
- Conditions
- Acute Kidney Injury, Chronic Kidney Diseases, Graft Failure
- Trial name
- NCT06340607
- Where
- South Korea
- Volunteers
- 3,422 people
- Sponsor
- Asan Medical Center
Benign or Preinvasive Uterine Disease
Study of Laparoendoscopic Single Site Hysterectomy in Benign and Preinvasive Uterine Disease
To compare the efficacy between single-port and three-port laparoscopic assisted vaginal hysterectomy in patients with benign or preinvasive uterine disease
- Trial name
- NCT01679548
- Testing
- Single-port LAVH, Three-port LAVH
- Where
- South Korea
- Volunteers
- 424 people
- Sponsor
- Asan Medical Center
Acute Kidney Injury, Hyperglycemia
Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation
This retrospective cohort study of patients classified by the blood glucose level after reperfusion in liver transplantation repicient.
- Conditions
- Acute Kidney Injury, Hyperglycemia, Hypoglycemia, End Stage Liver Disease
- Trial name
- NCT06320730
- Testing
- Observational study, records of blood glucose level after reperfusion
- Where
- South Korea
- Volunteers
- 3,790 people
- Sponsor
- Asan Medical Center
Dermal Fillers
Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds.
- Trial name
- NCT06310863
- Testing
- LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Multidrug- and Rifampicin-resistant Tuberculosis
BPaL(M) Regimen for the Treatment of MDR/RR-TB
The objective of this study is to analyze the efficacy of a new regimen using Bedaquiline, Pretomanid, Linezolid, and Moxifloxacin for 24 weeks or Bedaquiline, Pretomanid, Linezolid for 26 weeks for the treatment of MDR/RR-TB…
- Trial name
- NCT05381194
- Testing
- BPaL(M) regimen
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Asan Medical Center
Kidney Transplantation
ABO-Incompatible Kidney Transplants Between Robot-Assisted vs. Open Surgery
While robot-assisted kidney transplantation (RAKT) offers potential benefits such as minimal postoperative pain, better cosmesis, fewer wound infections, and shorter hospital stay, its efficacy in ABO-incompatible (ABO-i) KT…
- Trial name
- NCT06287008
- Testing
- robot-assisted kidney transplantation
- Where
- South Korea
- Volunteers
- 239 people
- Sponsor
- Asan Medical Center
Gastric Cancer
Adjuvant Capecitabine Versus Observation Alone in Curatively Resected Stage IB Gastric Cancer((KCSG ST14-05): CATALYSIS
multi-center, prospective, randomized, open-label phase III
- Trial name
- NCT01917552
- Testing
- capecitabine
- Where
- South Korea
- Volunteers
- 870 people
- Sponsor
- Asan Medical Center
Metastatic Gastric Cancer
GC 2nd Line Durvalumab(MEDI4736)/Tremelimumab Plus Paclitaxel Study
To evaluate safety and response rate of durvalumab/tremelimumab in combination with paclitaxel in patients with metastatic gastric cancers who fail a first-line chemotherapy
- Trial name
- NCT03751761
- Testing
- durvalumab, tremelimumab, paclitaxel
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Asan Medical Center
Gastric Cancer, Adjuvant Chemotherapy, XO
Compare Adjuvant Chemotherapy of Docetaxel/Capecitabine/Oxliplatin Versus Capecitabine/Oxaliplatin in Advanced Gastric Cancer at Stage IIIb and IV(KCSG ST15-08): TRIUMPH
multicenter, open label, randomaized, phase III The role of post surgery adjuvant chemotherapy is becoming more and more important in AGC (advance gastric cancer).
- Trial name
- NCT01935778
- Testing
- Docetaxel and capecitabine and oxaliplatin, capecitabine and oxaliplatin
- Where
- South Korea
- Volunteers
- 286 people
- Sponsor
- Asan Medical Center
Sclerotherapy, Endometrioma
Two-session Catheter-directed Sclerotherapy Using Ethanol for Endometrioma
The goal of this clinical trial is to evaluate the safety and clinical outcomes of two-session catheter-directed sclerotherapy (CDS) with 96% ethanol in patients with endometrioma.
- Trial name
- NCT06274086
- Testing
- Two-session catheter-directed sclerotherapy
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Enhanced Recovery After Surgery, Mortality
Impact of Anesthesia-related Enhanced Recovery After Surgery Components on Mortality After Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD), one of the most complex and invasive abdominal surgeries, is associated with long length of stay (LOS) and high morbidity and mortality rates.
- Trial name
- NCT06256133
- Testing
- Enhanced Recovery After Surgery protocol
- Where
- South Korea
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Hepatocellular Carcinoma Recurrent, Hepatocellular Carcinoma
Association Between Pre-op Non-Selective Beta-Blockers and Hepatocellular Carcinoma Recurrence Post-Liver Transplant
The goal of this observational study is to investigate the effect of non-selective beta-blocker (NSBB) on the recurrence of hepatocellular carcinoma (HCC) following liver transplantation in patients who underwent liver…
- Trial name
- NCT06233708
- Testing
- Non-Selective Beta-Adrenoreceptor Agonists for Systemic Use
- Volunteers
- 2,092 people
- Sponsor
- Asan Medical Center
Remimazolam, Propofol
Comparison of Recovery Profiles Among Propofol, Remimazolam, and Dexmedetomidine After Intraoperative Sedation
A total of 120 patients (American Society of Anesthesiologist Physical Status 1-3) who signed a consent form among patients aged 19-80 years who are scheduled to undergo brachial plexus block and upper extremity surgery under…
- Conditions
- Remimazolam, Propofol, Dexmedetomidine, Orthopedic Procedures
- Trial name
- NCT05688345
- Testing
- Remimazolam, Propofol, Dexmedetomidine
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Asan Medical Center
Colorectal Neoplasms, Neoplasm Metastasis
Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab
Liver is the most common site of metastases from colorectal cancer. Neoadjuvant chemotherapy with targeted agents is usually recommended for borderline-resectable liver metastases that are technically difficult to resect for…
- Conditions
- Colorectal Neoplasms, Neoplasm Metastasis, Colonic Neoplasms, Rectal Neoplasms
- Trial name
- CLIMB (NCT03698461)
- Testing
- Atezolizumab, Bevacizumab, Oxaliplatin
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Gastrointestinal Stromal Tumors
Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI
KIT exon 9 mutants had poorer survival compared with KIT exon 11 mutants when they were treated with the same dose of imatinib, 400 mg per day, and that patients with KIT exon 9 mutation had better progression-free survival with…
- Trial name
- NCT01541709
- Testing
- imatinib
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Asan Medical Center
Chronic Obstructive Pulmonary Disease
A Study About Association Between Microbiome, Metabolome and Clinical Characteristics in COPD Patients
The goal of this observational registry study is to compare characteristics of gut and sputum microbiome and metabolome among COPD patients with significant smoking history, COPD patients without significant smoking history and…
- Trial name
- NCT06101459
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Myelodysplastic Syndromes
CyFluATG in Lower Risk MDS
To evaluate the efficacy of the conditioning regimen with cyclophosphamide, fludarabine, and antithymocyte globulin (CyFluATG) for allogeneic hematopoietic cell transplantation (HCT) in patients with lower risk myelodysplastic…
- Trial name
- NCT06098326
- Testing
- cyclophosphamide, fludarabine, and antithymocyte globulin
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Patients With MDS, Acute Myeloid Leukemia (AML) Evolving From MDS, and Chronic Myelomonocytic Leukemia (CMML)
HCT With PTCy in Higher-risk MDS
This study is conducted to evaluate the efficacy of post-transplantation cyclophosphamide with myeloablative or reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplantation (HCT) in patients with…
- Trial name
- NCT06098313
- Testing
- Cyclophosphamide
- Where
- South Korea
- Volunteers
- 113 people
- Sponsor
- Asan Medical Center
Myelodysplastic Syndromes
Hematopoietic Cell Transplantation With Post-transplantation Cyclophosphamide in MDS
This study is conducted to evaluate the feasibility and efficacy of post-transplantation cyclophosphamide with myeloablative or reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplantation (HCT) in…
- Trial name
- NCT02969980
- Testing
- Cyclophosphamide
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center