Clinical trials: open to volunteers, sponsored by Assiut University
Breast Cancer, Postoperative Pain
Effect of Pectoral Nerve Block (PECS) Using Magnesium Sulfate Added to Dexamethasone on Quality of Recovery and Chronic Post-Mastectomy Pain
This prospective, randomized, double-blind, controlled clinical trial will evaluate whether adding magnesium sulfate to dexamethasone-augmented ultrasound-guided pectoral nerve block improves postoperative recovery and analgesia…
- Conditions
- Breast Cancer, Postoperative Pain, Chronic Postoperative Pain, Quality of Recovery
- Trial name
- NCT07923643
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Obesity and Diabetes Mellitus, Type 2, Albuminuria
Obesity-Related Indices and Albuminuria in Type 2 Diabetes
This cross-sectional study aims to evaluate obesity-related indices and albuminuria levels in patients with type 2 diabetes mellitus.
- Trial name
- NCT07922694
- Volunteers
- 349 people
- Sponsor
- Assiut University
Airway Edema, Postoperative Complications
Effect of Prophylactic Dexamethasone vs Placebo on Airway Dimensions Assessed by Ultrasonography in Patients Undergoing Laparoscopic Cholecystectomy
During laparoscopic surgery, the abdomen is inflated with carbon dioxide gas (pneumoperitoneum), which alters venous return and fluid distribution, potentially leading to swelling in the tissues of the upper airway.
- Conditions
- Airway Edema, Postoperative Complications, Cholecystolithiasis
- Trial name
- NCT07918495
- Testing
- Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Assiut University
Postoperative Pain, Shoulder Arthroscopy
Magnesium Sulphate as an Adjuvant in Combined Costoclavicular Block and Suprascapular Block Versus Interscalene Block for Ambulatory Shoulder Arthroscopy
Shoulder arthroscopy is a common outpatient procedure that can cause moderate to severe pain during the first 24 to 48 hours after surgery.
- Conditions
- Postoperative Pain, Shoulder Arthroscopy, Hemidiaphragmatic Paresis
- Trial name
- NCT07918521
- Testing
- Combined Costoclavicular and Suprascapular Nerve Block with Magnesium Sulfate, Interscalene Brachial Plexus Block with Magnesium Sulfate
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetic Nephropathy Type 2, Type 2 Diabetes Mellitus
Beta-2-Trace Protein in Diabetic Nephropathy
This cross-sectional study aims to evaluate serum beta-2-trace protein levels in patients with diabetic nephropathy compared with healthy controls.
- Trial name
- NCT07919795
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spondyloarthropathy
Identification of Serum Level of Glutathione Peroxidase 4
Analysis of the level of glutathione peroxidase 4 (GPX4) in ankylosing spondylitis and axial psoriatic arthritis patients. The association of glutathione peroxidase 4 (GPX4) with disease activity and severity in ankylosing…
- Trial name
- NCT06554392
- Testing
- Blood sample
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Assiut University
Cardiac Abnormalities, Nutrient Intake
Early Nutrition and Heart Structure and Function in Preterm Infants During the First Year of Life
Preterm infants are babies born before 37 completed weeks of pregnancy. Early nutrition is important for their growth and development, and it may also be associated with how their heart develops and functions during infancy.
- Trial name
- NCT07892209
- Testing
- echocardiography
- Volunteers
- 80 people
- Sponsor
- Assiut University
Acute Ischemic Stroke, Acute Haemorrhagic Stroke
Role of EEG in Differentiation Between Ischemic and Hemorrhagic Stroke
Searching electrical activity registered by EEG in acute ischemic and hemorrhagic stroke and comparing these parameters to the post-stroke recovery patterns to investigate the role of EEG as a differentiation tool and as a…
- Trial name
- NCT06984965
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Spinal Anaesthesia Induced Hypotension
Effect of Ondansetron on the Incidence of Spinal Anaesthesia-Induced Hypotension in Elderly Patients Undergoing Fracture Hip Surgery
This study aims to compare prophylactic intravenous ondansetron 4 mg versus placebo regarding the incidence of spinal anaesthesia-induced hypotension, defined as mean arterial pressure (MAP) fall >20% from baseline or systolic…
- Trial name
- NCT07914868
- Testing
- Ondansetron
- Where
- Egypt
- Volunteers
- 142 people
- Sponsor
- Assiut University
Postdural Puncture Headache (PDPH)
Oral Gabapentin Versus Intravenous Neostigmine/Atropine Versus Combination of Both for Prevention of PDPH
Post-dural puncture headache (PDPH) is a major complication of neuraxial anaesthesia. Pain is intense, frontal, throbbing, and radiates to the occiput; it is more severe when standing and less severe when lying down.
- Trial name
- NCT07916116
- Testing
- treatment of Postdural puncture headache
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Neoplasm Metastasis / Bone and Bones
Change in Fat Fraction Quantification Before and After Treatment in Bone Metastases
Bone metastases are a common and serious complication of cancer. Treatment response is currently judged mainly by delayed changes on CT scans or X-rays, a process that can take months and sometimes produces misleading results.
- Trial name
- NCT07848516
- Testing
- MRI Non-contrast
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Assiut University
STEMI, High Risk NSTEMI
Incremental Prognostic Utility of CBC-derived Inflammatory Indices After Incomplete Coronary Revascularization: Association With 12-months Cardiovascular Outcomes
Coronary artery disease (CAD) remains the top cause of death worldwide . While guideline-directed medical therapy forms the foundation of CAD treatment , revascularization via percutaneous coronary intervention (PCI) or coronary…
- Trial name
- CBCRSS2026 (NCT07916701)
- Volunteers
- 440 people
- Sponsor
- Assiut University
Bronchiectasis
Study of Bronchiectasis and Associated Cardiovascular Comorbidities
Effect of cardiovascular comorbidities on disease severity and quality of life in Patients with acute exacerbation of non-cystic fibrosis bronchiectasis
- Trial name
- NCT05783869
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Respiratory Distress Syndrome
Respiratory Distress and Elective Cesarean Section at Term
Cesarean section is a life-saving surgical operation for women and their newborns. In Egypt, caesarean sections are over-utilized. The rate increased from 27.6 % in 2008 to 51.8 % in 2014, reaching 72.2 % in 2021.
- Trial name
- NCT06874478
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Assiut University
Postoperative Pain
US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External…
- Trial name
- NCT05272280
- Testing
- External oblique intercostal (EOI) block, Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bladder Cancer, TURBT
Sequential Chemotherapy Followed by Ultrahypofractionated Radiotherapy for Muscle-Invasive Bladder Cancer
Muscle-invasive bladder cancer (MIBC) is a potentially lethal disease for which radical cystectomy with appropriate systemic therapy remains a standard curative approach in medically fit patients. .
- Conditions
- Bladder Cancer, TURBT, Radiotherapy
- Trial name
- NCT07914101
- Testing
- Transurethral Resection of Bladder Tumor, Sequential Systemic Chemotherapy, radiotherapy
- Volunteers
- 71 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea, Metabolic Dysfunction-Associated Steatotic Liver Disease
Association Between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea
Association between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea
- Trial name
- OSA/MAFLD (NCT07716995)
- Volunteers
- 127 people
- Sponsor
- Assiut University
Nutritional Effect on IBD Pregnant Patients
Impact of Nutritional Managment on Pregnancy With IBD Patients and Their Springs
While diet can support IBD management, with the potential to positively benefit perinatal as well as longer-term health outcomes, little is known about the quality of dietary patterns among pregnant women with IBD , therefore…
- Trial name
- IBD/pregnancy (NCT07560176)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Inguinal Hernia, Incarcerated Inguinal Hernia
Bassini Repair Versus Desarda Technique in Urgent Complicated Inguinal Hernia Repair
Inguinal hernias occur when abdominal contents, such as intestine or fat, protrude through a weakness in the lower abdominal wall.
- Conditions
- Inguinal Hernia, Incarcerated Inguinal Hernia, Strangulated Inguinal Hernia
- Trial name
- NCT07910240
- Testing
- Bassini Inguinal Herniorrhaphy, Desarda Inguinal Hernia Repair
- Volunteers
- 70 people
- Sponsor
- Assiut University
Major Depressive Disorder, Bipolar Disorder
Neurostructural and Biochemical Signatures of Tobacco Smoking in Mood Disorders
Tobacco smoking is significantly more common among individuals with mood disorders, such as major depressive disorder (MDD) and bipolar disorder, compared to the general population.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Tobacco Use Disorder, Mood Disorders
- Trial name
- NCT07910318
- Volunteers
- 240 people
- Sponsor
- Assiut University
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