Clinical trials: sponsored by Baylor Research Institute
Gaucher Disease Type 1, Gaucher Disease Type 3
The Effect of Velaglucerase Alfa (Vpriv) on Skeletal Development in Pediatric Gaucher Disease
The purpose of this trial is to study the effect of Velaglucerase Alfa on skeletal bone development of children with Type 1 or Type 3 Gaucher Disease.
- Trial name
- NCT02528617
- Testing
- Velaglucerase alfa
- Where
- United States
- Sponsor
- Baylor Research Institute
Fabry Disease
Fabry Screening Study
To determine if patients with a deficiency of alpha-galactosidase A are at-risk for cardiac complications that commonly occur in the general population
- Trial name
- NCT01019629
- Where
- United States
- Volunteers
- 2,724 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Acute Kidney Injury, Renal Insufficiency
Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE)
1. To examine two main predictor variables independently and then jointly in stratified and multivariate analyses for the outcomes of CSA-AKI, MARCE, need for RRT, and inpatient mortality, and the composite, as well as the…
- Trial name
- MARCE (NCT02332070)
- Testing
- cardiac surgery
- Where
- United States
- Volunteers
- 965 people
- Sponsor
- Baylor Research Institute
Traumatic Brain Injury
Imaging Dopamine Function and Its Impact on Outcome After Traumatic Brain Injury (TBI)
This study will examine resting dopamine function as well as dopamine response in the brain as it interacts with medicines normally prescribed to subacute Traumatic Brain Injury (TBI) patients.
- Trial name
- NCT01850290
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Baylor Research Institute
Postpartum Hemorrhage, Uterine Atony
Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Trial name
- NCT02229513
- Testing
- Uterine Cooling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Critical Limb Ischemia
Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia
The reason the investigators are doing this study is to compare the results of laser atherectomy versus angioplasty with or without the placement of a stent in the artery.
- Trial name
- NCT01579123
- Testing
- Angioplasty, Laser atherectomy
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Baylor Research Institute
Carotid Endarterectomy
Vascular Post Market Review
The primary objective of this study is to confirm that properties of CardioCel provide operative benefit to surgeons when compared to Dacron, CorMatrix, and all other bovine pericardium not treated with proprietary ADAPT…
- Trial name
- NCT02681341
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor Research Institute
Type 1 Diabetes
Pancreatic Islet Cell Transplantation
The purpose of this study is to assess a novel approach to immunosuppression in allogenic pancreatic islet cell transplant recipients.
- Trial name
- NCT00214786
- Testing
- Islet cell transplantation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor Research Institute
Prematurity, Very Low Birth Weight
The Safety Evaluation of Silver Alginate (Algidex™) Dressing in Very Low Birth Weight (VLBW) Infants
The purpose of this study is to test the safety of silver alginate (Algidex™) dressing in VLBW infants in preparation for a large efficacy trial.
- Trial name
- NCT00593684
- Testing
- Silver Alginate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor Research Institute
Aortic Stenosis
Prospective Balloon Aortic Valvuloplasty
The primary objective of this study is to determine the reasons for balloon aortic valvuloplasty (BAV) in the current clinical setting and to determine the outcomes of BAV in patients with aortic stenosis.
- Trial name
- BAV (NCT02122900)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Lymphedema
Aquatic Exercise Study for Breast Cancer Patients With Lymphedema
The purpose of this study is to determine what effects aquatic exercise has on participants with Lymphedema.
- Trial name
- NCT00498771
- Testing
- Aquatic Exercise arm
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Baylor Research Institute
HIV
Vaccination of HIV-1 Infected Patients With Dendritic Cells in Addition to Antiretroviral Treatment - (DALIA Trial)
The purpose of this study is to determine whether the administration of a dendritic cell vaccine is a safe and effective treatment for HIV-1 patients.
- Trial name
- NCT00796770
- Testing
- Dendritic Cell Vaccine
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor Research Institute
Lymphoma
Intratumoral Dendritic Cell Vaccination Combined With Local Radiotherapy in Patients With Recurrent Lymphoma.
The purpose of the study is to gather data on feasibility and on immune and clinical efficacy of intratumoral dendritic cell (DC) vaccination in combination with local radiotherapy in patients with recurrent lymphoma
- Trial name
- NCT00637117
- Testing
- Autologous dendritic cells generated using GM-CSF, interferon alpha and LPS
- Sponsor
- Baylor Research Institute
Aortic Valve Stenosis
Improving Echo Measurements in the Diagnosis of Aortic Stenosis
Aortic stenosis is a common valvular heart disease, affecting mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms…
- Trial name
- NCT02146755
- Where
- 2 sites in United States
- Volunteers
- 396 people
- Sponsor
- Baylor Research Institute
Outpatient Colonoscopy
A Study to Examine Levels of Sedation During Outpatient Colonoscopies
Examine levels of sedation required for patients to comfortably undergo colonoscopy using propofol and if adjunct monitoring equipment promotes patient safety.
- Trial name
- NCT00614263
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Aortic Stenosis
Low-dose-contrast Cardiac Computed Tomography
Low-dose-contrast CCTA can effectively and safely assess the aortic valve apparatus, and effectively direct the trans-catheter heart valve (THV) size selection by providing accurate annulus sizing, and provide adequate…
- Trial name
- CCTA (NCT02146768)
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Baylor Research Institute
Melanoma, Neoplasm Metastasis
Vaccination of Patients With Stage IV Melanoma With Dendritic Cells
The purpose of this study is to test a novel dendritic cell (DC) vaccine in patients with Stage IV melanoma.
- Trial name
- NCT00125749
- Testing
- Dendritic cell vaccination
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor Research Institute
Islet Cell Transplantation, Type 1 Diabetes
Pancreatic Islet Cell Transplantation - A Novel Approach to Improve Islet Quality and Engraftment
The purpose of this study is to assess a novel approach to immunosuppression in allogenic pancreatic islet cell transplant recipients.
- Trial name
- NCT00530686
- Testing
- Islet cell transplantation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Baylor Research Institute
Liver Insufficiency
Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors
The PI will study metabolism during liver regeneration in living liver donors
- Trial name
- NCT01922323
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Islet Cell Transplantation, Type 1 Diabetes
Pancreatic Islet Cell Transplantation After Kidney Transplantation - A Novel Approach to Immunosupression
The purpose of this study is to further test islet cell transplant in patients who have had a kidney transplant. This study will also evaluate the safety and effectiveness of the anti-rejection medications used to prevent…
- Trial name
- NCT03047200
- Testing
- Islet cell transplantation
- Where
- United States
- Sponsor
- Baylor Research Institute