Clinical trials: sponsored by Baylor Research Institute
Unbound Tacrolimus in Pregnant Uterus Transplant Recipients, Whole Blood Tacrolimus in Pregnant Uterus Transplant Recipients
Tacrolimus in Pregnancy
To create a formula that adjusts tacrolimus blood levels. This is needed because pregnant patients have higher levels of unbound tacrolimus.
- Trial name
- NCT07422012
- Testing
- Modeling of unbound and whole blood tacrolimus in pregnant uterus transplant recipients
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Baylor Research Institute
Diabetes, Diabetes Mellitus
Continuous Glucose Monitoring of Hospitalized Patients With Diabetes
Systematic continuous glucose monitoring (CGM) is commonly provided as a treatment option to patients with diabetes in ambulatory care settings yet is rarely provided during hospitalization.
- Conditions
- Diabetes, Diabetes Mellitus, Glucose, High Blood, Glucose, Low Blood
- Trial name
- NCT04230694
- Testing
- Dexcom Generation 6 CGM (Dexcom Gen6) device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor Research Institute
Aortic Valve Disease
Prospective Long-Term Outcomes of a Standardized Ross Procedure
This standardized prospective long-term outcome analysis will help reaffirm these findings via a multicenter patient cohort and describe the best practices/techniques for stabilization of the autograft and right ventricular…
- Trial name
- ROSS (NCT06352671)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Baylor Research Institute
BDE for Hernia Patients, Exparel for Hernia Patients
Hernia Abd Wall Recons - BDE vs Exparel
This trial compares how two different numbing medications help patients feel the least amount of pain while recovering from surgery.
- Trial name
- NCT07518238
- Testing
- BDE Injectable Drug, Exparel Injectable Drug
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Baylor Research Institute
Absolute Uterine Infertility
Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Infertility
This study aims to investigate the treatment of absolute uterine infertility (AUI) due to congenital or surgical absence of a uterus or presence of a nonfunctioning uterus.
- Trial name
- NCT02656550
- Testing
- Uterine Transplant
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Baylor Research Institute
Central Line Bloodstream Infections
The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants
The purpose of this study is to determine whether silver alginate (Algidex) patch is effective in the prevention of central line infections in very low birth weight infants.
- Trial name
- NCT00964093
- Testing
- Silver Alginate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Cancer
The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers.
The purpose of the Texas Immuno-Oncology Biorepository (TIOB) is to collect and store well-defined and well-annotated serial biospecimens of tissue, blood, urine and stool in a longitudinal manner from cancer patients who are…
- Trial name
- TIOB (NCT05371756)
- Where
- 8 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Baylor Research Institute
Achalasia, Esophageal, Esophagogastric Junction Outflow Obstruction
The Impact of Anesthetics on FLIP
To understand the impact of commonly used anesthetics on esophageal motility during FLIP topography.
- Conditions
- Achalasia, Esophageal, Esophagogastric Junction Outflow Obstruction, Spastic Esophageal Disorders
- Trial name
- NCT07458555
- Testing
- FLIP Imaging under various standard of care anesthetics in the context of endotracheal intubation.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor Research Institute
Spinal Cord Injuries, Obesity
The SEEA (SCI Energy Expenditure and Activity) Study
People with SCI are at higher risk of obesity and chronic diseases, such as hypertension, high cholesterol, diabetes and cardiovascular disease, than the general population.
- Conditions
- Spinal Cord Injuries, Obesity, Metabolic Syndrome, Cardiovascular Diseases
- Trial name
- SEEA (NCT04748835)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Baylor Research Institute
Spinal Cord Injuries, Upper Extremity Paresis
Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries
Texas Biomedical Device Center at UT Dallas has developed an innovative strategy to enhance recovery of motor and sensory function after neurological injury termed targeted plasticity therapy (TPT).
- Trial name
- NCT04288245
- Testing
- Active Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Quality of Life, Renal Insufficiency
A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children
The objective of this study is to obtain follow up data on a cohort of well-studied patients with Fabry disease who have been on ERT since childhood for a total of about 15 years.
- Conditions
- Quality of Life, Renal Insufficiency, Cardiac Event
- Trial name
- NCT04002531
- Testing
- General and Neurological examination, Vital signs, 12 lead electrocardiogram
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Baylor Research Institute
Diabetes Mellitus
Improving Diabetes Care:Effectiveness of Physician Profiling and Care Coordination by a Diabetes Resource Nurse
The purpose of this study is to test the effectiveness of physician profiling and care coordination by a diabetes resource nurse in improving the quality of diabetes care.
- Trial name
- NCT00258674
- Testing
- Medicare Claims Feedback, Medical Record Review, Diabetes Resource Nurse
- Where
- United States
- Volunteers
- 1,891 people
- Sponsor
- Baylor Research Institute
Cataract Diabetic, Macula Edema
Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes
This study aims to compare the effectiveness of Dextenza vs standard of care prednisolone taper after cataract surgery in diabetic patients with regards to controlling post-op inflammation at post-op days 7, 14, and 30.
- Trial name
- NCT04977427
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Dialysis Access Malfunction
Trial Comparing Angiography and Angiography With IVUS for Treatment of Hemodialysis Access Failures
The reason the investigators are doing this study is to compare the results of angiography versus angiography with intravascular ultrasound in dialysis grafts/fistulas that are blocked.
- Trial name
- NCT02056704
- Testing
- Angiography with IVUS
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Baylor Research Institute
Dissection of Thoracic Aorta
Feasibility of Endovascular Repair of Ascending Aortic Pathologies
The purpose of this early feasibility study is to investigate the outcome of selected patients with ascending thoracic aortic pathologies including type A aortic dissection, who are suitable for endovascular repair with the…
- Trial name
- PS-IDE (NCT03322033)
- Testing
- Valiant PS-IDE Stent Graft
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Baylor Research Institute
Signs and Symptoms, Respiratory
Improved Patient Safety Through Continuous Bi-channel RR and SpO2 Monitoring With Masimo Patient SafetyNet
The investigator intend to perform an observational study, by adding Respiratory Rate monitoring to an already existing Patient SafetyNet system with SpO2 (Oxygen Saturation) and PR (Pulse Rate) monitoring.
- Trial name
- SafetyNet (NCT03043911)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor Research Institute
Research Awareness, Qualitative Research
Connect Qualitative Interviews
Goal of the study is to conduct Qualitative Interviews to identify and address barriers to study enrollment from various communities in order to increase the effectiveness and reach of our research to all people in the USA.
- Trial name
- NCT07444411
- Testing
- Qualitative Interview, Qualitative Survey, Survey using a questionnaire.
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Hypertension, African Americans
Giving a Low Carbohydrate Diet to Overcome Hypertension
This study will test the preliminary efficacy of adding a very low carbohydrate dietary intervention to the evidence-based DPP-GLB on blood pressure reductions for lower-income AA men and women in a community-based clinic.
- Conditions
- Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
- Trial name
- GLOH (NCT04230928)
- Testing
- Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Cardiovascular Surgery, Pain, Postoperative
Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery
The purpose of this study is to find out what effects (good and bad) that the study medicine called "liposomal bupivacaine" has on subjects that are undergoing a sternotomy.
- Conditions
- Cardiovascular Surgery, Pain, Postoperative, Block
- Trial name
- NCT04333095
- Testing
- Liposomal bupivacaine, Normal Saline Flush, 0.9% Injectable Solution_#1
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Baylor Research Institute
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome
Among adult individuals with type 2 diabetes mellitus and at risk for heart failure with impaired relaxation of the heart mildly reduced kidney filtration function (Type 4 cardiorenal syndrome) this trial will evaluate the…
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT02251431
- Testing
- BYDUREON
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Baylor Research Institute