Clinical trials: sponsored by Baylor Research Institute
Cervical Intraepithelial Neoplasia
Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs)
The purpose of this study is to determine the safety, feasibility, and regression rate of using curcumin in patients with Cervical Intraepithelial neoplasias (CIN3).
- Trial name
- NCT02554344
- Testing
- Curcumin
- Where
- United States
- Sponsor
- Baylor Research Institute
COPD
Harmonica Playing Improves Quality of Life in Patients With COPD
15 patients who have completed the Baylor Martha Foster Lung Center Pulmonary Rehabilitation Program at least six months ago will be selected to participate in a 12 week training program with six months of follow up.
- Trial name
- NCT03442140
- Testing
- Harmonica playing
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Baylor Research Institute
ECMO, Heparin
Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study
This single-center, open-label study will evaluate the safety and efficacy of subcutaneous heparin anticoagulation compared to the standard of care systemic intravenous anticoagulation during veno-venous extracorporeal membrane…
- Conditions
- ECMO, Heparin, Respiratory Failure
- Trial name
- NCT04496362
- Testing
- subcutaneous heparin anticoagulation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Liver Transplant
Trial of Inhaled Nitric Oxide (iNO) on Ischemia / Reperfusion Injury During Orthotopic Liver Transplantation With Marginal Grafts
This study is being done to determine if patients receiving (iNO) will have increased liver function and less damage from IR than patients who do not receive (iNO).
- Trial name
- NCT01172691
- Testing
- Inhaled Nitric Oxide (iNO)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor Research Institute
Esophagogastric Junction Outflow Obstruction
Corticosteroid Effect on Achalasia Variant EGJOO
EGJOO is a disorder in which the muscles of the esophagus (swallowing tube) do not function in a coordinated fashion so that swallowed material does not pass easily into the stomach.
- Trial name
- NCT06588348
- Testing
- Steroid treatment, Esophageal Manometry, Survey
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Baylor Research Institute
Liver Disease, Heart Failure
Quantitative Evaluation of the Progression of Liver Disease, Using ShearWaveTM
Liver biopsy for the assessment of fibrosis has multiple limitations. Liver ShearWaveTM Elastography may provide a non-invasive, fast, and reproducible alternative for the quantitative assessment of liver fibrosis.
- Trial name
- NCT02070315
- Where
- United States
- Volunteers
- 1,247 people
- Sponsor
- Baylor Research Institute
Cirrhosis, End Stage Liver Disease
Functional Assessment in Liver Transplantation
In order to ensure the equity of the liver allocation process, it is important to create objective, scientifically validated markers of frailty in patients with end-stage liver disease that accurately predict patient outcomes.
- Trial name
- FrAILT (NCT03870568)
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- Baylor Research Institute
Mild Cognitive Impairment, Aortic Stenosis
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR).
- Trial name
- Neurcog TAVR (NCT05614986)
- Testing
- 5 minute Montreal Cognitive Assessment (mini MoCA)
- Where
- 4 sites in United States
- Volunteers
- 81 people
- Sponsor
- Baylor Research Institute
Carcinoma, Hepatocellular
Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer
This study is a prospective Phase IV study to determine if the use of Everolimus results in lower liver tumor recurrence and improved patient and graft survival after liver transplant for hepatocellular carcinoma (HCC).
- Trial name
- NCT02081755
- Testing
- Everolimus, Tacrolimus, Myfortic
- Where
- 9 sites in United States
- Volunteers
- 336 people
- Sponsor
- Baylor Research Institute
Living Liver and Kidney Donors
Living Organ Donor Recovery Enhancement Program
The purpose of the study is to test if using these living donor-specific pre-transplant resources would lead to a better and faster recovery post-transplant.
- Trial name
- NCT03865264
- Testing
- Recovery Enhancement Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Mucolipidosis Type IV
The Natural History of Mucolipidosis Type IV
The purpose of this study is to define the natural history of Mucolipidosis Type IV and identify potential clinical outcome measures.
- Trial name
- NCT01067742
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor Research Institute
Tobacco Use, Alcohol Abuse
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform
The goal of this study is to validate the TAPS-ESP as a screen and assessment that can be used in primary care for the screening and treatment of substance use.
- Conditions
- Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
- Trial name
- TAPS-ESP (NCT05476588)
- Testing
- Screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Aortic Valve Disease
A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease
For this study, blood and tissue samples will be collected in order to perform genetic testing to help researchers gather information about this disease and how and why it affects some patients more than others.
- Trial name
- NCT01194362
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Baylor Research Institute
Social Determinants of Health, Major Depressive Disorder
The Role of Social Determinants in Cardiovascular Health and Vascular Function
This study aims to identify the influence of social determinants of health domains on vascular function in a low income, racial, and ethnic minority population at risk for disparities.
- Conditions
- Social Determinants of Health, Major Depressive Disorder, Cardiovascular Diseases
- Trial name
- CVRRC (NCT05772221)
- Testing
- Screening
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Mild Cognitive Impairment, Alzheimer Disease
Discovery of Novel Biomarkers That Will Lead to the Early Detection of Alzheimer's Disease
This study will perform a targeted metabolic analysis in blood and urine samples from subjects attending the Baylor AT\&T Memory Center.
- Trial name
- BVB (NCT03136679)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Liver Transplant Recipients
Blood Draw Study for Liver Transplant Patients
The purpose of this study is to see what a lab test will show and if there is a way to predict which patients will be more likely to have rejection after receiving a liver transplant.
- Trial name
- NCT01525797
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Weight Loss, Bariatric Surgery Candidate
Resting Metabolic Rate Testing in Bariatric Surgery Patients
This study evaluates if measuring resting metabolic rate (the number of calories the body burns at rest) before surgery can help predict successful weight loss after surgery.
- Trial name
- NCT03221543
- Testing
- ReeVue Indirect Calorimeter
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Pneumonia, Interstitial
Study Testing Convalescent Plasma vs Best Supportive Care
Currently there are no proven treatment option for COVID-19. Human convalescent plasma is an option for COVID-19 treatment and could be available from people who have recovered and can donate plasma.
- Trial name
- NCT04333251
- Testing
- high-titer anti-Sars-CoV-2 plasma, oxygen therapy
- Sponsor
- Baylor Research Institute
Uterine Atony
Exploration and Determination of Genomic Markers Predictive of Uterine Atony
The primary objective of this study is to determine whether there are markers in the tissue of atonic uteri, and in the patients' plasma that would help identify patients likely to suffer postpartum hemorrhage due to uterine…
- Trial name
- NCT03413917
- Testing
- Analysis of genomic markers in uterine atony
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Breast Cancer
DWIBS-MRI: An Adjunct to the Traditional Diagnostic Breast Imaging Evaluation
1.1. Primary Objectives To determine if MRI DWIBS can accurately identify suspicious lesions previously categorized on mammography and sonography as potentially malignant.
- Trial name
- DWIBS (NCT04491864)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute