Clinical trials: sponsored by Baylor Research Institute
Ventricular Flutter, Atrioventricular Block
Pacemaker Utilization and Ventricular Pacing in Patients Undergoing Trans-catheter Aortic Valve Replacement (TAVR)
The purpose of this study is to assess the incidence (at 90-days) of ventricular pacing in patients undergoing permanent pacemaker placement after TAVR.
- Conditions
- Ventricular Flutter, Atrioventricular Block, Intraventricular Conduction Delay, Bundle Branch Block
- Trial name
- PPM in TAVR (NCT02994667)
- Testing
- Permanent Pacemaker Placement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor Research Institute
Paravalvular Leak, Transcatheter Valve Replacement
Paravalvular Leak for Transcatheter Valve Replacement
The study objective is to assess the agreement between cMRI PVL grading (based on regurgitant fraction) and TTE PVL grading (based on pressure half-time and the ratio of the jet arc to the circumference of the annulus).
- Trial name
- PVL-TAVR (NCT02079129)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Baylor Research Institute
Spinal Cord Injuries
Workout on Wheels Internet Intervention (WOWii)
Project WOWii examines how useful and effective an online format is for helping people with SCI get more exercise over 4 months.
- Trial name
- NCT03189095
- Testing
- WOWii (Workout on Wheels Internet Intervention)
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Human Microbiota, PreTerm Birth
The Reproductive Microbiome & Perinatal Health Outcomes
Pregnant African American women between 18 and 45 years of age will be enrolled at 20 weeks of gestation or less. Biological specimens (vaginal swabs, rectal swab) will be collected at enrollment, 23-24 weeks, at 28-29 weeks, and…
- Conditions
- Human Microbiota, PreTerm Birth, Human Gastrointestinal Microbiota, Metabolomics
- Trial name
- NCT02948192
- Testing
- Survey, Sample collection
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Obesity, Pre-diabetes
Better Me Within Trial to Improve Lifestyle Behaviors in African Americans
This study describes a community-based participatory research (CBPR) approach to design a novel faith-enhancement to the diabetes prevention program (DPP) for AA women.
- Trial name
- NCT04082702
- Testing
- Faith-enhanced diabetes prevention program, Standard diabetes prevention program
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Baylor Research Institute
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use
TAPS-ESP: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use Electronic Spanish Platform
This Phase 1 STTR project will develop a technology platform for delivering the TAPS Tool to a Spanish-speaking, health disparity population in a community health center.
- Trial name
- TASP-ESP (NCT03879785)
- Testing
- Screening
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Acquired Brain Injury
Neurocognitive Rehabilitation Using Virtual Reality
Objective: To determine whether immersive virtual reality (VR) treatment interventions improve executive dysfunction and complex attention deficits in patients with brain injury compared with standard neurorehabilitation, and…
- Trial name
- NCT04017091
- Testing
- Virtual Reality Cognitive Training
- Volunteers
- 33 people
- Sponsor
- Baylor Research Institute
Acute Kidney Injury, Heart Failure
Effectiveness of NephroCheckTM Test to Predict Acute Kidney Injury Following Advanced Cardiac Replacement Therapies
The purpose of this study is to test how well the NephroCheckTM Test, a noninvasive laboratory test performed on urine, predicts loss of kidney function in patients that have had a heart transplant or a Left Ventricular Assist…
- Trial name
- NCT02827448
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Baylor Research Institute
Stroke
Self Directed Stations for the Stroke Patient
Early initiation of therapy post stroke has been associated with improved long-term outcomes, and functional activity dose during the first week of inpatient rehabilitation predicts both gait velocity at discharge and length of…
- Trial name
- NCT02446197
- Testing
- Patient Directed Exercise Group
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Baylor Research Institute
Lower Urinary Tract Symptoms, Lower Urinary Tract Infection
PEEZY Midstream Urine Device Compared to Catheterized Urine Sample
Urine culture and microscopic urinalysis will be compared between 2 collection methods: PEEZY midstream urine collection, and urethral catheter collection.
- Trial name
- PEEZY (NCT03729336)
- Testing
- Midstream urine collection device, Catheter for urine collection
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Atrial Fibrillation
Cryoballoon and Associated Esophageal Effects
The primary objectives are to determine the correlation between rate of temperature decline and nadir cryoballoon temperatures rate of temperature decline and nadir esophageal temperatures during pulmonary vein isolation.
- Trial name
- NCT03960346
- Testing
- Ablation with cryoenergy
- Volunteers
- 2 people
- Sponsor
- Baylor Research Institute
Atrial Fibrillation
CareLink Express (CLE Research)
The primary objective of this research is to determine if evaluating CIEDs using CareLink Express® can lead to shorter time to interrogation in the Emergency Department compared to evaluation of devices using traditional…
- Trial name
- CLE (NCT03223207)
- Volunteers
- 60 people
- Sponsor
- Baylor Research Institute
Severe Obesity
Determinants of Fat Malabsorption After Roux-en-Y Gastric Bypass
The purpose of this study is to determine whether or not the length of the biliopancreatic limb of the Roux-en-Y anastamosis plays a critical role in the development of malabsorption after gastric bypass for treatment of severe…
- Trial name
- NCT01252511
- Testing
- RYGB for surgical treatment of severe obesity
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Glioblastoma
Prognosis and Therapeutic Biomarkers for Glioblastoma Patients
The purpose of this study is to investigate if the potential biomarkers identified could be used for facilitating the diagnosis and prognosis of patients with glioblastoma (GBM).
- Trial name
- NCT03403803
- Testing
- Optune
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor Research Institute
Leukodystrophies
Natural History of the Leukodystrophies
The purpose of this study is to: 1. define novel homogeneous groups of patients with LDs and 2. work toward finding the cause of these disorders.
- Trial name
- NCT02843555
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor Research Institute
Pancreatic Cancer
Dendritic Cell Vaccine and Chemotherapy for Patients With Pancreatic Cancer
The primary objective is to confirm clinical safety and feasibility of combining the antigen-loaded Dendritic Cell (DC) vaccine with chemotherapy including folinic acid, oxaliplatin, irinotecan and 5-Fluorouracil (5FU)…
- Trial name
- PancVax (NCT02548169)
- Testing
- DC Vaccine + Standard of Care Chemotherapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor Research Institute
Educational Problems, Medication Adherence
Impact of Telehealth Warfarin Education on Patient Retention
The objective of this study is to evaluate the effectiveness of telehealth warfarin education in a charity outpatient clinic. The purpose is to increase patient knowledge with regard to their warfarin therapy and to measure…
- Trial name
- NCT03650777
- Testing
- Warfarin Telehealth Education
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Atrial Fibrillation
Proper Extent of Maze Intercaval Lesion
It's hypothesized that a mean and range distance from the cavo-atrial junction to the area where there is complete loss of conductive tissue can be measured to better inform surgeons performing the Cox-Maze procedure.
- Trial name
- Maze (NCT03091205)
- Where
- United States
- Sponsor
- Baylor Research Institute
Hyperhomocysteinemia
Effect of S-adenosylmethionine (SAMe) on Blood Levels of Homocysteine
The purpose of this study is to investigate whether S-adenosylmethionine (SAMe), a natural substance available as a nutritional supplement, can influence blood levels of homocysteine (Hcy).
- Trial name
- NCT00473200
- Testing
- S-adenosylmethionine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Baylor Research Institute
Adult Polyglucosan Body Disease, Glycogen Brancher Enzyme Deficiency
Triheptanoin Treatment Trial for Patients With Adult Polyglucosan Body Disease
The purpose of the study is to determine if triheptanoin is an effective treatment for the symptoms of Adult Polyglucosan Body Disease.
- Conditions
- Adult Polyglucosan Body Disease, Glycogen Brancher Enzyme Deficiency, Glycogen Storage Disease Type IV
- Trial name
- NCT00947960
- Testing
- Triheptanoin, Vegetable Oil
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Baylor Research Institute