Clinical trials: sponsored by Beijing Anzhen Hospital
Congenital Heart Disease
A Comprehensive Registry Study of the Whole Life Cycle of Patients With CHD
This observational study aims to collect data on the prevalence, intervention, and prognosis of congenital heart disease (CHD) in Chinese patients across their entire lifecycle.
- Trial name
- NCT06611787
- Where
- China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Cardiovascular Disease, Type 2 Diabetes Mellitus
PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study
The association between Cardiovascular Disease (CVD) and Chronic Kidney Disease (CKD) is well established. Traditional risk factors for CVD and CKD are similar, with type 2 diabetes mellitus (T2DM) being the most prevalent risk…
- Trial name
- PLACARD (NCT06336239)
- Where
- 27 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Anzhen Hospital
Persistent Atrial Fibrillation, Catheter Ablation
Comparison Between Upgraded '2C3L' vs. PVI Approach for Catheter Ablation of Persistent Atrial Fibrillation
Catheter ablation has emerged as an important treatment option for patients with symptomatic atrial fibrillation (AF). Pulmonary vein antral isolation (PVI) is now considered the cornerstone technique of AF ablation and has shown…
- Trial name
- PROMPT-AF (NCT04497376)
- Testing
- upgraded '2C3L', pulmonary vein antral isolation
- Where
- 12 sites in China
- Volunteers
- 498 people
- Sponsor
- Beijing Anzhen Hospital
Dyslipidemias, Gas Detection Method
Accuracy Assessment of a Novel Gas Detection Approach in Dyslipidemia Diagnosis
This study aims to validate the feasibility and accuracy of a novel gas detection method for dyslipidemia screening by analyzing the lipid profile of human breath metabolites.
- Trial name
- NCT06486857
- Testing
- a novel gas detection method for dyslipidemia screening
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Ventricular Tachycardia
Catheter Ablation of Haemodynamically Not-tolerated Electrical Storm in Structural Heart Disease
This is a multi-center, parallel-group, randomized, open-label trial evaluating the clinical outcome and efficacy of emergency catheter ablation versus conventional stepped-care strategies in patients with haemodynamically…
- Trial name
- NCT06455020
- Testing
- Catheter ablation, Stepped-care strategies
- Where
- 4 sites in China
- Volunteers
- 96 people
- Sponsor
- Beijing Anzhen Hospital
New Onset Atrial Fibrillation, Complications; Cardiac, Postoperative
Nifekalant Versus Amiodarone in New-Onset Atrial Fibrillation After Cardiac Surgery
Postoperative atrial fibrillation is a major complication of cardiac surgery, which could lead to high morbidity and mortality, increase duration of hospital stay and increase the cost of treatment.
- Trial name
- NCT05169866
- Testing
- Nifekalant, Amiodarone
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Beijing Anzhen Hospital
Cognitive Impairment, Atrial Fibrillation
Atrial Fibrillation Follow-up Investigation to Recover Memory and learnING Trial
The objective of the study is to evaluate the effectiveness of cognitive training in people with atrial fibrillation and cognitive decline over 12-week cognitive training.
- Trial name
- AFFIRMING (NCT05374642)
- Testing
- cognitive training, active control
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Anzhen Hospital
Aortic Stenosis
Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis
Calcific aortic stenosis (CAS) can cause severe adverse cardiac events, but there are currently no effective drugs that can prevent or delay the progression of the disease.
- Trial name
- NCT04968509
- Testing
- PCSK9 inhibitors and statins with or without ezetimibe, Statins with or without ezetimibe
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Beijing Anzhen Hospital
Cardiogenic Shock
Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)
Extracorporeal membrane oxygenation (ECMO) is of great value in supporting patients with cardiac shock. More than 80% ECMO patients will develop renal catastrophe that continuous renal replacement therapy (CRRT) is required.
- Trial name
- ELITE (NCT03549923)
- Testing
- Simultaneous CRRT, Conventional-indication CRRT, Esmolol
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Beijing Anzhen Hospital
Cardiogenic Shock, Cardiac Arrest
China Extracorporeal Life Support Registry
Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique of providing effective cardiac and respiratory support to patients with lungs and/or heart failure.
- Conditions
- Cardiogenic Shock, Cardiac Arrest, Heart Failure, Acute Respiratory Distress Syndrome
- Trial name
- NCT04158479
- Testing
- ECMO
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Beijing Anzhen Hospital
Hypertension, Medication Therapy Management
Efficacy of Pharmacist Interventions Through the "Medication Therapy Management Pathway in Hypertensive Patients"
The goal of this Randomized Controlled Trial is to carry out in adult patients with primary hypertension whose blood pressure control is not up to standard.
- Trial name
- PharmMTMH (NCT06310512)
- Testing
- Structured drug therapy management
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Beijing Anzhen Hospital
Mild Cognitive Impairment, Coronary Heart Disease
Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment
In this study, a multicentre, double-blind, randomized controlled study based on cognitive training was conducted in patients with coronary heart disease and cognitive impairment but without dementia， to evaluate the…
- Trial name
- COG-T CHD (NCT05735041)
- Testing
- Multi-domain cognitive digital therapy, Basic cognitive therapy
- Where
- 8 sites in China
- Volunteers
- 224 people
- Sponsor
- Beijing Anzhen Hospital
Aortic Dissection
Angiotensin II Pathway and Postoperative Hypoxemia
Acute type A aortic dissection is often accompanied by postoperative hypoxemia, the cause of which is not fully understood. Angiotensin II is an important component of the renin-angiotensin system (RAS), which has been suggested…
- Trial name
- NCT05055570
- Testing
- No intervention
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Myocardial and Arterial Phenotype of Coronary Artery Disease
The CAD-MAP (Myocardial and Arterial Phenotype of Coronary Artery Disease) registry is initiated with the goal to describe the cardiac imaging map including epicardial coronary artery, coronary microcirculation and myocardium…
- Trial name
- CAD-MAP (NCT06202300)
- Testing
- Inflammation burden
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Beijing Anzhen Hospital
Atrial Fibrillation, Hypertension
Cardiovascular Risk Reduction in Atrial Fibrillation Trial
Atrial fibrillation (AF) is a serious public health problem because of its increasing incidence and prevalence in the aging population.
- Trial name
- CRAFT (NCT04347330)
- Testing
- Intensive BP Control, Standard BP Control
- Where
- China
- Volunteers
- 1,675 people
- Sponsor
- Beijing Anzhen Hospital
Cardiogenic Shock
Hemoperfusion in Extracorporeal Membrane Oxygenation (ECMO) Patients
Extracorporeal membrane oxygenation (ECMO) is a temporary mechanical circulatory support device for cardiogenic shock (CS) patients.
- Trial name
- NCT03729765
- Testing
- hemoperfusion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Rota China Registry
Rotational atherectomy (RA) facilitates percutaneous coronary intervention for complex de novo lesions with severe calcification.
- Trial name
- NCT03806621
- Testing
- Rotational Atherectomy
- Where
- 19 sites in China
- Volunteers
- 980 people
- Sponsor
- Beijing Anzhen Hospital
Angina Pectoris, Real World Study
Registry Study of Medical Therapy in Patients With Angina Pectoris(GREAT)
The study will be a multi-center, prospective, cohort study based on registration of Chinese angina pectoris patients. After signing the informed consent, all patients will be screened as per the inclusion and exclusion criteria.
- Trial name
- NCT05050773
- Where
- 10 sites in China
- Volunteers
- 1,556 people
- Sponsor
- Beijing Anzhen Hospital
Congenital Heart Disease in Pregnancy, Prenatal Diagnosis
The National Program for the Improvement of Management of Fetal Congenital Heart Disease in China
To investigate and evaluate the capacity of prenatal screening, diagnosis and counseling of congenital heart disease in medical institutions in China, in order to understand the current status and existing problems of prenatal…
- Conditions
- Congenital Heart Disease in Pregnancy, Prenatal Diagnosis, Fetal Echocardiography
- Trial name
- NCT05940363
- Testing
- Improvement on Prenatal Screening and Treatment Capabilities for Congenital Heart Disease with a Comprehensive Diagnosis and Treatment Program Incorporating New Technologies
- Volunteers
- 9,000 people
- Sponsor
- Beijing Anzhen Hospital
STEMI - ST Elevation Myocardial Infarction
Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI
The RIGHT study is a large randomized study dedicated to post-PPCI anticoagulation in STEMI patients. The investigators propose to evaluate the clinical efficacy and safety of anticoagulation prolonged for at least 48 hours after…
- Trial name
- RIGHT (NCT03664180)
- Testing
- Bivalirudin, Enoxaparin, Unfractionated heparin
- Where
- China
- Volunteers
- 2,989 people
- Sponsor
- Beijing Anzhen Hospital