Clinical trials: sponsored by Beijing Tiantan Hospital
Acute Stroke, Transient Ischemic Attack
Intensive Medical Therapy for High-risk Intracranial or Extracranial Atherosclerosis
Large-artery stenosis plays an important role in the occurrence of ischemic stroke. The primary purpose of this study is to evaluate the efficacy and safety of intensive antiplatelet therapy versus standard antiplatelet therapy…
- Trial name
- INSPIRES (NCT03635749)
- Testing
- Intensive antiplatelet, Standard antiplatelet, Immediate high-intensity statin
- Where
- 113 sites in China
- Volunteers
- 6,100 people
- Sponsor
- Beijing Tiantan Hospital
X-linked Adrenoleukodystrophy
Registry of X-linked Adrenoleukodystrophy
This study is a observational study conducted through recruiting X-linked adrenoleukodystrophy (X-ALD) patients, to build a comprehensive evaluation and long-term follow-up platform for X-ALD patients, and to provide a…
- Trial name
- NCT05939232
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Osteoarthritis, Knee, Chronic Pain
Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis Patients
Intra-articular injection of corticosteroid and hyaluronic acid is a common treatment for osteoarthritis of the knee. As a treatment drug for patients with depression, duloxetine has been shown in many studies to effectively…
- Trial name
- NCT04117893
- Testing
- Duloxetine, intra-articular injection of corticosteroid and hyaluronic acid
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Esketamine, Pregabalin
Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.
Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. severe postoperative pain can significantly impair patients' quality of life, social functioning and contribute to…
- Conditions
- Esketamine, Pregabalin, Acute Postoperative Pain, Neurosurgical Procedures
- Trial name
- NCT05096468
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Coma, Stroke
Short-term Cervical Spinal Cord Stimulation in Patients With Disorders of Consciousness After Intracerebral Hemorrhage
Disorders of consciousness (DOC) refers to the persistent loss of consciousness after 28 days in patients with brain injury caused by trauma, stroke, or hypoxia. It includes coma, vegetative state, and minimally conscious state.
- Trial name
- SCS-ICH (NCT05922644)
- Testing
- SCS, Conventional
- Where
- China
- Volunteers
- 344 people
- Sponsor
- Beijing Tiantan Hospital
PD - Parkinson's Disease
Effects of Propofol on Brain Function in Patients With Parkinson's Disease
Propofol is a short-acting general anesthetic drug commonly used in clinical practice, with rapid clinical onset of action, amnesic, anxiolytic, antiepileptic, and muscle relaxant effects.
- Trial name
- NCT05895019
- Testing
- Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Tiantan Hospital
Intracerebral Hemorrhage
Efficacy and Safety Study: Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Movement Disorders in Patients With Intracranial Hemorrhage (ICH).
This pilot study aims to assess the effectiveness and safety of rTMS in the treatment of movement disorders in patients with ICH.
- Trial name
- NCT05920473
- Testing
- rTMS with Magstim Rapid 2 magnetic stimulation device
- Where
- 3 sites in China
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Pituitary Neoplasms
Desflurane and Anesthesia Recovery Period in Endonasal Endoscopic Pituitary Adenoma Resection
Nasal packing is required after endoscopic pituitary adenoma resection. The patient can only breathe through the mouth. The blood and secretion in the nasal cavity may be inhaled into the trachea after the operation.
- Trial name
- NCT05088252
- Testing
- Desflurane, Propofol
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm, Cerebrovascular Disease
Aspirin Treatment for Small Unruptured InTracranial Aneurysms With Ischemic cereBrovascuLar diseasE
The management of small unruptured intracranial aneurysms (UIA) with ischemic cerebrovascular disease (ICVD) has been a very controversial topic in neurosurgery.
- Trial name
- AT-SUITABLE (NCT05907902)
- Testing
- Aspirin Enteric-coated Tablets
- Where
- 2 sites in China
- Volunteers
- 824 people
- Sponsor
- Beijing Tiantan Hospital
Dexmedetomidine, Postoperative Delirium
Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Disease
Postoperative delirium (POD) is a common complication, and the incidence of POD after deep brain stimulation(DBS) implementation ranges from 10% to 40%.
- Conditions
- Dexmedetomidine, Postoperative Delirium, Deep Brain Stimulation
- Trial name
- NCT05197439
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Beijing Tiantan Hospital
Glioma
Evaluate the Accuracy of Raman IVD Analyzer in the Diagnosis of Gliomas During Surgery
Compare the data obtained from the Raman analyzer and paraffin pathology examination on the same external brain tissue sample. Evaluate the effectiveness and safety of the Raman analyzer for intraoperative diagnosis gliomas of…
- Trial name
- NCT05901844
- Testing
- Paraffin pathological diagnosis
- Volunteers
- 256 people
- Sponsor
- Beijing Tiantan Hospital
Posterior Circulation Brain Infarction
Choice of Anesthesia for Endovascular Treatment of Acute Ischemic Stroke in Posterior Circulation
There is few randomized controlled clinical to investigated the impact of anesthetic type on outcome in patients with acute ischemic stroke in posterior cerebral circulation.
- Trial name
- CANVAS-II (NCT03317535)
- Testing
- General anesthesia, Local anesthesia/concious sedation, Spontaneous breath
- Where
- 2 sites in China
- Volunteers
- 93 people
- Sponsor
- Beijing Tiantan Hospital
Rebound Pain, Dexamethasone
The Effect of Intercostal Nerve Block With Dexamethasone and Ropivacaine on Rebound Pain After Thoracoscopic Surgery
Regional nerve block is one of the commonly used methods for postoperative analgesia after thoracoscopic surgery. Recent studies have found that rebound pain may occur after regional block, which is defined as acute postoperative…
- Conditions
- Rebound Pain, Dexamethasone, Intercostal Nerve Block, Thoracoscopic Surgery
- Trial name
- NCT05825378
- Testing
- Dexamethasone 8mg+0.375% ropivacaine, 0.375% ropivacaine
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm
A Retrospective, Multicenter, Controlled Clinical Trail: to Evaluate the Clinical Efficiency of Intracranial Aneurysm Assistive Software in the Morphological Measurement
the goal of this clinical trail is to evaluate the clinical efficiency of intracranial aneurysm assistive software in the morphological measurement. The trail is designed as retrospective, multicenter, controlled clinical trail.
- Trial name
- NCT05804474
- Testing
- Observational study
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke
A Safety and Effective Study of Ginkgolides Diterpene Lactone Meglumine Injection in the Treatment of Ischemic Stroke.
The aim of this study is to evaluate the safety and effectivity of Ginkgo diterpene lactone meglumine injection tn the treatment of acute ischemic stroke
- Trial name
- NCT02526225
- Testing
- Ginkgo diterpene lactone meglumine injection, Ginkgo diterpene lactone meglumine injection simulation
- Where
- China
- Volunteers
- 3,452 people
- Sponsor
- Beijing Tiantan Hospital
Fluid Therapy, Brain Edema
Effects of Intraoperative GDFT on the Postoperative Brain Edema
Whether a fluid protocol aiming for protecting vital organ perfusion or fluid restriction is favorable to post-craniotomy outcomes such as brain edema remains uncertain.
- Conditions
- Fluid Therapy, Brain Edema, Brain Tumor
- Trial name
- NCT03323580
- Testing
- GDFT, traditional fluid therapy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative, Neurosurgery
Preemptive Infiltration With Betamethasone and Ropivacaine for Postoperative Pain in Laminoplasty or Laminectomy
Laminoplasty and laminectomy have been used for decades for the treatment of intraspinal space occupying lesions, spinal stenosis, disc herniation, injuries, etc.
- Trial name
- NCT04153396
- Testing
- The Treatment group, The Control group
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Beijing Tiantan Hospital
Trigeminal Neuralgia
5% Lidocaine-medicated Plaster for the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN) is characterized by sudden, severe, usually unilateral, transient, stinging, recurrent electrocute-like shock in one or more divisions of the trigeminal nerve, lasting from a few seconds to less than 2…
- Trial name
- NCT04570293
- Testing
- 5% lidocaine medicated plaster, vehicle plaster
- Where
- 5 sites in China
- Volunteers
- 226 people
- Sponsor
- Beijing Tiantan Hospital
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment
Background: Despite the capability of emergency surgery to reduce the mortality of severe spontaneous intracranial hemorrhage (SSICH) patients, the effect and safety of surgical treatment for severe spontaneous intracranial…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05766865
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital
Brain Diseases
Multi-center Study of Artificial Intelligence Model for Gadolinium-based Contrast Agent Reduction in Brain MRI (MAGNET)
MAGNET is a multi-center and prospective study to minimize Gadolinium-based Contrast Agent (GBCA) combining novel artificial intelligence (AI) methods with pre-contrast images and/or low-dose images to synthesize virtual…
- Trial name
- MAGNET (NCT05754476)
- Testing
- Low-dose GBCA levels
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital