Clinical trials: sponsored by Beijing Tongren Hospital
Head and Neck Squamous Cell Carcinoma
Efficacy and Safety of PD-1 Plus Chemotherapy in Poorly Differentiated Locally Advanced (LA) HNSCC
Patients with locally advanced (stage III to stage IVB) poorly differentiated head and neck squamous cell carcinoma (excluding nasopharyngeal carcinoma) who meet the inclusion criteria will have their blood samples collected…
- Trial name
- NCT06100497
- Testing
- Pembrolizumab, Cisplatin, Paclitaxel-albumin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital
Dry Eye
Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction
Objective: To evaluate the effect of transcutaneous auricular vagus nerve stimulation (taVNS) for the patients with dry eye disease with meibomian gland dysfunction. Methods: We enrolled 270 patients at Beijing Tongren Hospital.
- Trial name
- NCT06544447
- Testing
- taVNS, Hyaluronic acid eye drops
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Beijing Tongren Hospital
Postoperative Pulmonary Complications
Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery
Background: Postoperative pulmonary complications (PPCs) may extend the length of stay of patients and even increase perioperative mortality after video-assisted thoracoscopic (VATS) pulmonary surgery.
- Trial name
- NCT05922449
- Testing
- Thoracic Paravertebral Block
- Where
- 2 sites in China
- Volunteers
- 302 people
- Sponsor
- Beijing Tongren Hospital
Meniere Disease
Transcutaneous Auricular Vagus Nerve Stimulation for Meniere Disease
Objective: To evaluate the effect of Transcutaneous auricular vagus nerve stimulation for the patients Meniere disease. Methods: We enrolled 231 patients at Beijing TongRen Hospital.
- Trial name
- NCT06544590
- Testing
- taVNS, Betahistine Mesylate tablet
- Where
- China
- Volunteers
- 77 people
- Sponsor
- Beijing Tongren Hospital
Traumatic Facial Paralysis
Laser Acupuncture for Traumatic Facial Paralysis
Objective: The objective of this study was to determine whether laser acupuncture therapy could relieve symptoms in patients with traumatic facial paralysis.
- Trial name
- NCT06544603
- Testing
- Multiwave Locked System (MLS) laser
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Beijing Tongren Hospital
Meniere Disease
Laser Acupuncture for Meniere Disease
Objective: To evaluate the effect of laser acupuncture for the patients Meniere disease. Methods: We enrolled 324 patients at Beijing Tongren Hospital.
- Trial name
- NCT06544434
- Testing
- Multiwave Locked System (MLS) laser (Mphi laser, ASA Srl, Vicenza, Italy), Betahistine Mesylate tablet
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Beijing Tongren Hospital
Neuro-Ophthalmology
Prediction Model of Microvascular Ischemic Ocular Motor Nerve Palsy and Inflammatory Ocular Motor Nerve Palsy in Chinese Patients
This study aimed to train and validate deep learning systems (DLS) to differentiate between microvascular ischemic ocular motor nerve palsy (v-OMNP) and inflammatory ocular motor nerve palsy (i-OMNP).
- Trial name
- NCT06518096
- Where
- China
- Volunteers
- 299 people
- Sponsor
- Beijing Tongren Hospital
Myopia Progression
Factors Influencing Physiological Hyperopia in Children
The trend of myopia in children and its low age is a major social and public health problem in China. More seriously, retinopathy associated with high myopia has become the number one cause of irreversible blinding eye disease in…
- Trial name
- NCT06498947
- Testing
- This study was observational with no intervention.
- Where
- China
- Volunteers
- 1,006 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Postoperative Complications
GDFT on the Postoperative Outcome in Head and Neck Cancer Surgery
The goal of this clinical trial is to evaluate whether goal-directed fluid therapy (GDFT) can improve the postoperative recovery in patients undergoing head and neck cancer surgery.
- Trial name
- NCT06468852
- Testing
- Goal-Directed Fluid Therapy
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Beijing Tongren Hospital
Meniere Disease
Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Meniere Disease
Objective: To evaluate the effect of Transcutaneous auricular vagus nerve stimulation for the patients Meniere disease. Methods: We accrued 25 patients at Beijing TongRen Hospital.
- Trial name
- NCT04686695
- Testing
- taVNS
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tongren Hospital
Chromatic Adaptation
Visual Health Evaluation of Natural Color Display Technology
Study on visual fatigue and visual function under changing ambient light color temperature by natural color mode: The influence of electronic display devices on visual fatigue of human eyes is the main evaluation index and the…
- Trial name
- NCT06394102
- Testing
- The automatic color temperature adjustment mode equipped on terminal display devices can reduce the discrepancy between the color temperature of the device and the ambient light.
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type, T-lymphoblastic Lymphoma
Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma
The patients diagnosed with relapsed/refractory or advanced NK/T-cell Lymphoma (r/r NKTCL) were selected as the research objects.
- Trial name
- NCT06376721
- Testing
- Linperlisib, Camrelizumab, Pegaspargase
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Beijing Tongren Hospital
Orbital Neoplasms
Risk Stratification of Orbital Tumors Based on MRl and Artificial Intelligence
Orbital tumors can be categorized into benign and malignant tumors, and there are significant variations in their biological behavior, treatment, and prognosis.
- Trial name
- NCT06336499
- Testing
- Multi-parametric MRI and image analysis by deep learning or machine learning algorithms
- Volunteers
- 600 people
- Sponsor
- Beijing Tongren Hospital
Fetal Acidemia
Application of High-flow Nasal Oxygen in Cesarean Section
The study propose that the using the high-flow nasl oxygen to provide oxygen for maternal can improve the fetal acidemia and the neonatal outcomes during cesarean section with combined spinal-epidural anesthesia.
- Trial name
- NCT05921955
- Testing
- Optiflow high-flow nasal cannula system
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Goal-directed Fluid Therapy
Stroke Volume Variation- Guided Hemodynamic Therapy Versus Oxygen Extraction Ratio-guided Hemodynamic Therapy
The FloTrac/Vigileo is a minimal invasive device assessing flow based hemodynamic parameters by pulse contour analysis based on the radial artery pressure signal.
- Trial name
- NCT05487924
- Testing
- SVV-GDHT, O2ER-GDHT, conventional care
- Volunteers
- 610 people
- Sponsor
- Beijing Tongren Hospital
Bell's Palsy
Photobiomodulation Therapy for Idiopathic Facial Paralysis
Objective: Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected…
- Trial name
- NCT05585346
- Testing
- MLS laser, Oral vitamin B1
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Beijing Tongren Hospital
All-cause Mortality
ADL and CONUT for Predicting 1-year Mortality Risk in Older Adults After Hip Fracture
Hip fracture has a serious impact on the quality of life and even the survival of older adults. The multidisciplinary management of hip fracture has been shown to be effective in improving patient outcome and cost-effective in…
- Trial name
- NCT05814172
- Testing
- no intervention
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Beijing Tongren Hospital
Head and Neck Squamous Cell Carcinoma, Neoadjuvant Therapy
Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC
This study is a prospective, open-label, multi-center phase III study; patients with untreated stage IIIA to stage IVB head and neck squamous cell carcinoma (including oral cavity cancer, oropharyngeal cancer, hypopharyngeal…
- Conditions
- Head and Neck Squamous Cell Carcinoma, Neoadjuvant Therapy, Pembrolizumab
- Trial name
- NCT06102395
- Testing
- Pembrolizumab, Cisplatin, Carboplatin
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Beijing Tongren Hospital
Allergic Rhinitis
A Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis
Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of the nasal mucosa mainly mediated by immunoglobulin E after exposure to allergens in atopic individuals.
- Trial name
- MERAK (NCT05470647)
- Testing
- Interleukin-4 receptor responders 1, Interleukin-4 receptor responders 2
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Beijing Tongren Hospital
B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma
CD19/CD22 Bispecific CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma or Acute Lymphoblastic Leukemia
CAR-T cell therapy targeting CD19 has been shown to be effective in heavily-pretreated B-cell ALL or NHL, but relapses post-CAR-T are common, and CD19 antigen loss is one of the reasons.
- Conditions
- B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma, Diffuse Large B Cell Lymphoma
- Trial name
- NCT06081478
- Testing
- CD19/CD22-bispecific CAR-T cells
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital