Clinical trials: open to volunteers, sponsored by Beijing Tongren Hospital
Pre-myopia
The Efficacy of a Polarized Folded Optical Path-based Reading-writing Desk for Myopia Prevention and Control in Pre-myopic Children
The goal of this clinical trial is to evaluate the efficacy and safety of the polarized folded optical path reading and writing device in myopia prevention onset in 5-10 year old children with pre myopia.
- Trial name
- NCT07914114
- Testing
- Polarized folded optical path reading and writing device, Eye-care desk lamp and desk posture corrector
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Endophthalmitis, Infectious Endophthalmitis
Vitrectomy Combined With Povidone-Iodine Vitreous Irrigation for Infectious Endophthalmitis
Infectious endophthalmitis is a severe infection inside the eye that can rapidly cause permanent vision loss or loss of the eye.
- Trial name
- NCT07888205
- Testing
- Povidone-iodine intravitreal irrigation with povidone-iodine containing 0.0025% available iodine, BSS intravitreal irrigation solution
- Volunteers
- 38 people
- Sponsor
- Beijing Tongren Hospital
Soft Tissue Sarcoma
Preliminary Clinical Study of Entinostat in Children With Malignant Soft Tissue Sarcoma Harboring PAX-family Gene Abnormalities
Pediatric soft tissue sarcomas (STS) are a group of malignant tumors originating from primitive mesenchymal tissues and account for approximately 7% of childhood cancers.
- Trial name
- NCT07888114
- Testing
- Entinostat, VAC/VTC chemotherapy
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Beijing Tongren Hospital
High Myopia
SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High Myopia
This clinical trial aims to determine whether a combination of overnight orthokeratology lenses and daytime myopia-control spectacles is more effective than myopia-control spectacles alone in slowing myopia progression and…
- Trial name
- NCT07854366
- Testing
- SmoothCore Technology Orthokeratology Combined with M.O.V.E. Lenses, M.O.V.E. Lenses Alone
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Screening for Hyperopic Reserve in Kindergarten
Screening for hyperopic reserve among senior kindergarten children is an important population-based eye health measure. Hyperopic reserve refers to physiological hyperopia in young children, which acts as a natural buffer against…
- Trial name
- NCT07851532
- Where
- China
- Volunteers
- 134,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Primary Sjögren's Syndrome (pSS)
Exploratory Study on the Efficacy and Safety of Low-Dose Blinatumomab in the Treatment of Moderate to Severe Primary Sjögren's Syndrome
The goal of this clinical trial is to learn if blinatumomab works to treat moderate-to-severe primary Sjögren's Syndrome. It will also learn about the safety of low-dose blinatumomab.
- Trial name
- NCT07852234
- Testing
- Blinatumomab, background treatment
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Tongren Hospital
Encephalitis Autoimmune
Efgartigimod in Anti-NMDA Receptor Encephalitis.
This study is a multicenter, open-label, single-arm exploratory trial designed to enroll 20 eligible patients with anti-NMDAR encephalitis.
- Trial name
- ANSWER (NCT07822776)
- Testing
- Efgartigimod Alfa
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Tongren Hospital
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
China CRSwNP Registry Study
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammatory disease of the nose and sinuses that can cause nasal blockage, loss of smell, nasal discharge, facial discomfort, sleep problems, and reduced…
- Trial name
- POLARIS (NCT07795658)
- Testing
- Routine Clinical Care for CRSwNP
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital
Chronic Dacryocystitis
Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis
This study aims to evaluate the safety and effectiveness of an absorbable lacrimal sac drug-eluting stent placed at the osteotomy site during endoscopic endonasal dacryocystorhinostomy (E-DCR) in patients with recurrent chronic…
- Trial name
- NCT07499791
- Testing
- Absorbable Lacrimal Sac Drug-Eluting Stent, Conventional Ostium Packing with Budesonide Nasal Spray
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Tongren Hospital
Myopia, Prevention and Control
Effectiveness of Digital Defocus Vision Training With Low-Concentration Atropine on the Prevention and Control of Myopia in Children: A Clinical Study
Based on existing theories of myopia development and progression, our preliminary work has leveraged the features of virtual reality (VR) technology to digitally simulate myopic defocus signals through image-based emulation.
- Trial name
- NCT07724210
- Testing
- For the experimental group,Virtual reality-based digital defocus training combined with 0.02% atropine eye drops, For the control group, one drop of 0.02% atropine eye drops was instilled into each eye at bedtime daily, combined with full-time wear of fully corrected multi-zone positive optical defocus (DIMS) spe
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Dry Eye
Perfluorohexyloctane Eye Drops vs. Sodium Hyaluronate for Video Display Terminal-Associated Dry Eye
This is a prospective, multicenter, open-label, randomized controlled trial designed to evaluate the efficacy and safety of perfluorohexyloctane (PFHO) eye drops (Hengqin®, Chengdu Shengdi Pharmaceutical Co., Ltd.) compared with…
- Trial name
- NCT07679685
- Testing
- 0.1% Sodium Hyaluronate Eye Drops, Perfluorohexyloctane Eye Drops (PFHO)
- Where
- 9 sites in China
- Volunteers
- 159 people
- Sponsor
- Beijing Tongren Hospital
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Preoperative Stapokibart for Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Nasal Polyps
This is a single-center, randomized, double-blinded, placebo-controlled clinical trial in adults with moderate-to-severe chronic rhinosinusitis with nasal polyps (CRSwNP) who have no previous nasal surgery.
- Trial name
- NCT07616609
- Testing
- Stapokibart
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Beijing Tongren Hospital
HNSCC
Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC
This is a single-arm, phase Ib study involving HNSCC patients who had received first-line treatment with either PD-1 combined with platinum-based drugs or PD-1 monotherapy.
- Trial name
- LONG'E (NCT07040072)
- Testing
- Stapokibart and Finotonlimab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Tongren Hospital
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Extranodal NK/T-cell Lymphoma
Selinexor Combined With Reduced-Dose Radiotherapy For Early-Stage Extranodal NK/T-Cell Lymphoma
Extranodal NK/T-cell lymphoma (ENKTCL) is an Epstein-Barr virus-associated non-Hodgkin lymphoma with high incidence in Asia and Latin America.
- Trial name
- NCT07554482
- Testing
- Pegaspargase (PEG) Asparaginase, Gemcitabine (GEM), Oxaliplatin
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Primary Central Nervous System Lymphoma (PCNSL), Diffuse Large B Cell Lymphoma (DLBCL)
Pomalidomide, Anti-PD-1 Antibody Combined With Selinexor (PPS) in Relapsed/Refractory Primary Central Nervous System Diffuse Large B-Cell Lymphoma
Primary central nervous system diffuse large B-cell lymphoma (PCNSL-DLBCL) is a highly aggressive malignancy accounting for over 80% of primary CNS lymphomas, with an annual incidence of 0.4-0.6 per 100,000 people globally and a…
- Trial name
- NCT07523737
- Testing
- Pomalidomide, PD-1 / PD-L1 monoclonal antibody, XPO1 inhibitor
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Beijing Tongren Hospital
Extranodal NK T Cell Lymphoma, Hemophagocytic Lymphohistiocytosis (HLH)
Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)
Extranodal NK/T-cell lymphoma (NKTCL) is an aggressive EBV-associated lymphoma with poor prognosis, highly prevalent in China. Early-stage NKTCL achieves favorable long-term survival, while advanced disease shows dismal outcomes…
- Trial name
- NCT07525466
- Testing
- Mitoxantrone liposome, Etoposide, Pegaspargase (PEG) Asparaginase
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Beijing Tongren Hospital
Neuromuscular Blocking Agents
Antagonism of Neostigmine in Continuous Infusion of Mivacurium
In this study, the antagonism of neostigmine, a cholinesterase inhibitor, on continuous infusion of mivacurium during foot and ankle surgery under general anesthesia was investigated, and the appropriate time point of antagonism…
- Trial name
- NCT07524959
- Testing
- Neostigmine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Emergence Agitation
Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children
This study investigates whether auricular acupressure can reduce postoperative emergence agitation among preschool children following adenoidectomy.
- Trial name
- NCT07472764
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital