Clinical trials: sponsored by Benha University
Traumatic Brain Injury, Rebound Intracranial Hypertension
ONSD Trajectory in Rebound ICH
The goal of this prospective observational study is to determine whether the trajectory of optic nerve sheath diameter (ONSD) after osmotherapy weaning can predict rebound intracranial hypertension in adult patients with…
- Conditions
- Traumatic Brain Injury, Rebound Intracranial Hypertension, Cerebral Edema
- Trial name
- ONSD/ INH (NCT07722702)
- Testing
- Optic Nerve Sheath Diameter Ultrasonography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Endophthalmitis, Endophthalmitis Postoperative
Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-Intravitreal Injection Endophthalmitis
This prospective comparative interventional study evaluated the anatomical and visual outcomes of phacovitrectomy versus pars plana vitrectomy (PPV) alone in patients with post-intravitreal injection endophthalmitis.
- Conditions
- Endophthalmitis, Endophthalmitis Postoperative, Intravitreal Injection Patients
- Trial name
- NCT07717944
- Testing
- Phacovitrectomy, Pars plana vitrectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Glandular Urethral Disassembly, Tubularized Incised Plate
Comparison Between Glandular Urethral Disassembly Versus Tubularized Incised Plate for Primary Distal Hypospadius Repair
To compare Glandular Urethral Disassembly technique versus Tubularized Incised Plate technique for Primary Distal Hypospadius Repair
- Conditions
- Glandular Urethral Disassembly, Tubularized Incised Plate, Distal Hypospadius Repair
- Trial name
- NCT05913128
- Testing
- Glandular Urethral Disassembly technique
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Benha University
GIT Function, Cholecystectomy, Laparoscopic
Dexamethasone, Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn the effect of Dexamethasone and Dexmedetomidine and Their Combination on Post op. GIT Function Measured by I-FFED Score Post Laparoscopic Cholecystectomy What medical problems do…
- Conditions
- GIT Function, Cholecystectomy, Laparoscopic, Dexamethasone, Dexmedetomidine
- Trial name
- vomiting (NCT07329933)
- Testing
- Dexamethasone, Dexmedetomidine, Dexamethasone and dexmedetomidine
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Shockwave Therapy
Role of Urine PH in Shock Wave Lithotripsy Outcomes in Renal Stone Disease
urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients. Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones < 2 cm.
- Trial name
- PHESWL (NCT07711028)
- Testing
- Shock Wave Iithotripsy, Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Benha University
LMA, Ventilation
First Attempt Insertion Success of Novel Two Person Lateral Rotation Technique V.S Standard Brain Technique for LMA Insertion
The goal of this clinical trial is to learn if two person lateral rotation technique of LMA insertion is more successful than the standard technique in achieving effective ventilation on the first introduction of the LMA .The…
- Trial name
- LMA insertion (NCT07715708)
- Testing
- LMA insertion by Standard technique, LMA insertion by Two-Person Lateral Rotation Technique
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Post Tonsillectomy Emergence Agitation
Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric
The goal of this clinical trial is to learn if melatonin can decrease emergence agitation in pediatric post tonsillectomy. The main questions it aims to answer are: Does melatonin decrease emergence agitation in pediatric post…
- Trial name
- NCT07375342
- Testing
- Melatonin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Digital Eye Strain (DES), Computer Vision Syndrome
Digital Eye Strain in Online Learning and Remote Work Environments: A Systematic Review
This systematic review aims to evaluate the prevalence of digital eye strain (DES) among individuals engaged in online learning and remote work, identify associated demographic, behavioral, environmental, and ocular risk factors…
- Trial name
- DES-OLRW (NCT07707908)
- Testing
- Systematic Literature Review
- Where
- Egypt
- Volunteers
- 8,972 people, healthy volunteers welcome
- Sponsor
- Benha University
Diabetic Retinopathy, Diabetic Macular Edema (DME)
AI Prediction of Treatment Response in DME
Diabetic macular edema (DME) is a leading cause of vision loss among individuals with diabetes mellitus. Although intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is the standard treatment for…
- Trial name
- NCT07707856
- Testing
- Artificial Intelligence-Based Imaging Analysis
- Where
- Egypt
- Volunteers
- 1,284 people
- Sponsor
- Benha University
Gynecological Cancer, Oocyte Cryopreservation
Digital Health Literacy and Oocyte Cryopreservation Among Women With Gynecological Cancer
This study evaluated a digital health literacy education intervention related to oocyte cryopreservation among newly diagnosed women with gynecological cancer.
- Conditions
- Gynecological Cancer, Oocyte Cryopreservation, Digital Health Literacy, Fertility Preservation
- Trial name
- NCT07701252
- Testing
- Digital Health Literacy Education Intervention
- Where
- Egypt
- Volunteers
- 158 people
- Sponsor
- Benha University
Pain Management, Pain After Surgery
Melatonin on Post Operative Pain After CS
The goal of this clinical trial is to learn if melatonin will decrease pain after C.S. The main questions it aims to answer are: Does melatonin lower the number of times participants need to use a rescue analgesia? What medical…
- Conditions
- Pain Management, Pain After Surgery, Cesarean Section Pain
- Trial name
- CS (NCT07380568)
- Testing
- Melatonin 5 mg, Melatonin 10 mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Primary Congenital Glaucoma, Pediatric Glaucoma
Subscleral Trabeculectomy With Inverted T-Shaped Deep Sclerectomy for Primary Congenital Glaucoma
Primary congenital glaucoma (PCG) is a vision-threatening disorder of childhood characterized by elevated intraocular pressure (IOP) resulting from developmental abnormalities of the anterior chamber angle.
- Conditions
- Primary Congenital Glaucoma, Pediatric Glaucoma, Intraocular Pressure
- Trial name
- TDS-PCG (NCT07701278)
- Testing
- Subscleral Trabeculectomy Combined With Inverted T-Shaped Deep Sclerectomy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Benha University
Septic Shock
Continuous Infusion Versus Intermittent Bolus Hydrocortisone in Septic Shock
Septic shock is a life-threatening condition in which infection causes dangerously low blood pressure and organ dysfunction despite fluid resuscitation and vasopressor treatment.
- Trial name
- NCT07695337
- Testing
- Hydrocortisone Continuous Infusion, Hydrocortisone Intermittent Bolus
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Benha University
Diabetic Vitreous Hemorrhage, Intravitreal Injections
Outcomes of Intravitreal Ranibizumab Injection for Diabetic Vitreous Hemorrhage
This prospective interventional cohort study evaluates the outcomes of intravitreal ranibizumab injection in patients with diabetic vitreous hemorrhage secondary to proliferative diabetic retinopathy.
- Conditions
- Diabetic Vitreous Hemorrhage, Intravitreal Injections, Ranibizumab
- Trial name
- RANI-VH (NCT07690800)
- Testing
- Ranibizumab
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Diabete Mellitus, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Impact of Pilates Exercises on Diabetic Erectile Dysfunction.
Erectile dysfunction (ED) has a prevalence of 52.5% in diabetic male patients, as described in a meta-analysis of 145 studies, including 88,577 men with type 1 and type 2 diabetes.
- Conditions
- Diabete Mellitus, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Pilates Exercise, Pelvic Floor Muscle Exercise
- Trial name
- PilatesDED2025 (NCT07293156)
- Testing
- Pilate Exercises, Home based pelvic floor muscle training, Sildenafil therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Anti-VEGF Treatment, Ranibizumab
Effectiveness of Biosimilar Ranibizumab in the Management of Diabetic Macular Edema
Diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. Anti-VEGF agents are widely used to improve vision and reduce retinal swelling.
- Conditions
- Anti-VEGF Treatment, Ranibizumab, Biosimilar
- Trial name
- ERBDME (NCT07663370)
- Testing
- Ranibizumab biosimilar
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Alopecia Areata
Assessment of Interleukin-15 and Interferon Gamma in Alopecia Areata Before and After Baricitinib.
The primary objective of this study was to evaluate the change in serum interferon gamma and Interleukin-15 levels before and after use of oral drug baricitinib therapy.
- Trial name
- Alopecia (NCT07645430)
- Testing
- Baricitinib 4 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Benign Prostatic Hyperplasia
BOTOX Injection Technique for LUTS Due to BPH
his prospective, randomized comparative study evaluated whether a combined Botulinum Toxin Type A (BOTOX) injection technique provides superior outcomes compared to injecting the prostatic parenchyma alone for patients with…
- Trial name
- BOTOX-BPH (NCT07645456)
- Testing
- Botulinum Toxin Type A (BoNT-A)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Prostate, Benign Prostatic Hyperplasia (BPH)
Inverted-T Incision With Early Apical Release vs. Three-Lobe in Holmium Laser Enucleation of The Prostate
Aim of the work is to compare the surgical efficacy and perioperative outcomes of the inverted-T incision with early apical release technique versus the standard three-lobe technique in patients undergoing Holmium Laser…
- Trial name
- NCT07642063
- Testing
- inverted-T with early apical release technique, standard three-lobe technique
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University
Extubation Failure
Noninvasive Ventilation Versus High-Flow Nasal Cannula After Extubation in High-Risk ICU Patients
Extubation failure is associated with increased morbidity and mortality in critically ill patients. High-risk patients may benefit from preventive respiratory support after extubation.
- Trial name
- NIV-HFNC (NCT07630766)
- Testing
- NIV, HFNC
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Benha University