Clinical trials: sponsored by Benha University
Postoperative Delirium (POD), Intracranial Hypertension
Low Pneumoperitoneum Pressure for Delirium Prevention in Elderly Laparoscopy
A randomized, double-blind trial comparing low (8-10 mmHg) versus standard (14 mmHg) intraabdominal pressure during laparoscopic pelvic surgery in patients aged 60 and older.
- Trial name
- NCT07906444
- Testing
- Low Intraabdominal Pressure Pneumoperitoneum, Standard Intraabdominal Pressure Pneumoperitoneum
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Benha University
Kidney Stones, Surgical Blood Loss
Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy is a minimally invasive surgical procedure used to remove large kidney stones. Although it is an effective treatment, bleeding during and after the procedure remains one of the main concerns and may…
- Conditions
- Kidney Stones, Surgical Blood Loss, Percutaneous Nephrolithotomy
- Trial name
- NCT07582341
- Testing
- Tranexamic acid, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Pregnancy, Health Literacy
Mobile Assisted Education on Prenatal Health
This study aims to evaluate the effect of mobile-assisted education on prenatal health literacy, health behaviors, and childbirth outcomes among primigravida women
- Conditions
- Pregnancy, Health Literacy, Mobile Assisted Education, Health Behavior
- Trial name
- NCT07900152
- Testing
- Mobile-Assisted Education
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release in Bipolar Enucleation of the Prostate
Bipolar enucleation of the prostate is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence (SUI), Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-BIPO (NCT07893548)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Benha University
Central Serous Retinopathy (CSR), Sub-Threshold Laser
Treatment of Recurrent and Multifocal Central Serous Chorioretinopathy
The goal of this clinical trial is to learn if subthreshold micropulse laser is a safe, effective, and painless treatment for multifocal and recurrent central serous chorioretinopathy (CSCR) in adults.
- Trial name
- NCT07889518
- Testing
- 577 nm Subthreshold Micropulse Laser
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Pain After Extracorporeal Shock Wave Lithotripsy, Palmitoylethanolamide
Palmitoylethanolamide vs Ibuprofen for Pain After ESWL
Pain after extracorporeal shock wave lithotripsy (ESWL), a non-surgical procedure used to treat kidney stones, is common and is usually treated with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen.
- Trial name
- NCT07316660
- Testing
- Palmitoylethanolamide (PEA), Ibuprofen (Brufen®)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Peritonitis Infectious
Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes
This study aims to evaluate the prognostic significance of CLI in predicting 28-day mortality and other outcomes in critically ill patients who develop post-operative abdominal sepsis.
- Trial name
- NCT07232342
- Testing
- Capillary Leak Index Versus
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Pain Management
Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries
Total hip arthroplasty (THA) has been one of the most significant advancements in orthopedic surgery over the past century. hip fractures are typically associated with severe pain, effective analgesia is crucial both before and…
- Trial name
- NCT07467356
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Renal Stone, Treatment Side Effects
Efficacy and Safety of Narrow Focus (F1) Versus Wide Focus (F3) of Shock Wave Lithotripsy (SWL) for Renal Calculi
This study aims to compare the narrow focus (F1) versus the wide focus (F3) in terms of the efficacy of Shock Wave Lithotripsy (SWL) in the management of renal calculi 1-2 cm and their injurious effect on the kidney.
- Trial name
- NCT04759599
- Testing
- Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Preemptive, Postoperative Timing
Preemptive and Postoperative Timing of Real-Time Sonar Guided Caudal Anesthesia for Pediatric Infra-Umbilical Procedures Analgesia
This study compared preemptive and postoperative real-time ultrasound-guided caudal block with respect to analgesic efficacy, opioid consumption, and hemodynamic stability in children undergoing infra-umbilical procedures.
- Conditions
- Preemptive, Postoperative Timing, Real-Time, Sonar
- Trial name
- NCT07853339
- Testing
- Caudal block immediately following induction of general anesthesia, Caudal block at the end of surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Ovarian Cysts, Endometriosis
Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts
We will conduct this study to estimate the effect of laparoscopic cystectomy on ovarian reserve in endometriotic cysts versus non-endometriotic cysts.
- Conditions
- Ovarian Cysts, Endometriosis, Benign Ovarian Cyst, Ovarian Reserve
- Trial name
- NCT07686783
- Testing
- Laparoscopic Ovarian Cystectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Prostate Cancer, Lower Urinary Tract Symptoms (LUTS)
Concomitant Trans-Perineal Prostate Biopsy and Ablation (Bioblation) for Prostate Cancer
This prospective study aims to validate the clinical outcomes of performing a concomitant trans-perineal prostate biopsy and laser ablation (termed "Bioblation") during a single session.
- Conditions
- Prostate Cancer, Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia
- Trial name
- Bioblation (NCT07526675)
- Testing
- Bioblation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Macular Hole Surgery
Autologous Tenon's Capsule Graft for Refractory Macular Holes
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes.
- Trial name
- ATCG-RMH (NCT07318961)
- Testing
- Autologous Tenon's Capsule Graft Placement
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Preeclampsia, Cesarean Birth
Norepinephrine Infusion vs Bolus vs Ephedrine for Blood Pressure Stability During Cesarean Delivery in Women With Preeclampsia
This randomized controlled trial will compare norepinephrine infusion, norepinephrine bolus, and ephedrine bolus for maintaining hemodynamic stability during spinal anesthesia for scheduled cesarean delivery in women with…
- Conditions
- Preeclampsia, Cesarean Birth, Hypotension During Surgery
- Trial name
- NCT07842783
- Testing
- Norepinephrine (0.05 μg/kg/min), Norepinephrine 4mcg, Ephedrine Bolus 6 mg
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Benha University
Phacoemulsification Cataract Surgery, Capsular Tension Ring
Capsular Tension Ring With Hydrophilic Versus Hydrophobic Intraocular Lenses
This study compares three approaches to cataract surgery. Cataract surgery involves removing the eye's cloudy natural lens and replacing it with an artificial intraocular lens (IOL) to restore clear vision.
- Conditions
- Phacoemulsification Cataract Surgery, Capsular Tension Ring, IOL Implantation
- Trial name
- CTR-IOL-3ARM (NCT07842809)
- Testing
- Hydrophilic acrylic intraocular lens (Eyecryl), Capsular tension ring (Auroring CTR 11), Hydrophobic acrylic intraocular lens (AcrySof IQ)
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Benha University
Ectopic Pregnancy
Sequential vs. Combined Letrozole and Methotrexate for Tubal Ectopic Pregnancy.
This study evaluates two medical strategies designed to minimize surgical intervention and reduce methotrexate (MTX) exposure in women with undisturbed tubal ectopic pregnancy (TEP).
- Trial name
- NCT07842796
- Testing
- Letrozole, Methotrexate
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Benha University
Stricture Urethra
The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence
The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence
- Trial name
- prp vs VIU (NCT07837167)
- Testing
- PRP injection, VIU
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Sepsis, Septic Shock
Comparing Blood-Based Ratios for Predicting Outcomes in Sepsis and Septic Shock
Sepsis and septic shock are serious conditions associated with a high risk of organ dysfunction and death. Simple laboratory-based markers may help identify critically ill patients who are at greater risk of poor outcomes.
- Trial name
- NCT07819708
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Endotracheal Intubation
Dexmedetomidine Versus Lidocaine for Optic Nerve Sheath Diameter During Craniotomy Intubation
Endotracheal intubation during general anesthesia can cause temporary increases in heart rate, blood pressure, and intracranial pressure. These changes may be particularly important in patients undergoing craniotomy.
- Trial name
- NCT07820540
- Testing
- Dexmedetomidine, Lidocaine, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Lumbar Disc Herniation, Lumbosacral Radiculopathy
Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain
This study will compare three fluoroscopy-guided epidural steroid injection approaches for adults with unilateral lumbosacral radicular pain caused by lumbar disc herniation.
- Trial name
- NCT07813988
- Testing
- High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Benha University