Clinical trials: sponsored by Benha University
Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection
Effect of Use of Probiotics on Systemic Infection in Critically Ill Patients: a Double Blind, Randomized, Placebo-controlled Trial
The primary goal of this study is to assess the benefit of probiotics in preventing or minimizing of various type of systemic infection in critically ill adult patients.
- Conditions
- Ventilator Acquired Pneumonia, Catheter Related Bloodstream Infection, Urinary Tract Infection, Diarrhea
- Trial name
- NCT07164781
- Testing
- Bacillus clausii, Sugar tablets
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Ventilator-Associated Pneumonia, Severe Pneumonia
Fiberoptic Bronchoscopy in Severe Ventilator-associated Pneumonia
This randomized controlled trial evaluated the clinical effect of fiberoptic bronchoscopy in the management of adult patients with severe ventilator-associated pneumonia (VAP).
- Conditions
- Ventilator-Associated Pneumonia, Severe Pneumonia, Critical Illness
- Trial name
- NCT07149909
- Testing
- Other (Conventional Therapy), Fiberoptic Bronchoscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Ulcerative Colitis
Rutin Therapy Role in Reducing Ulcerative Colitis Severity
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by oxidative stress and recurring inflammation in the colon. The condition can become chronic, spread, and lead to other complications.
- Trial name
- NCT07147842
- Testing
- Rutin 500 MG, fecal calprotectin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Respiratory Insufficiency, Weaning, Ventilator
Parasternal Intercostal Ultrasound vs RSBI for Weaning Prediction
Mechanical ventilation is essential in the management of critically ill patients, but deciding the proper time to wean and extubate remains a significant challenge.
- Conditions
- Respiratory Insufficiency, Weaning, Ventilator, Respiration, Artificial, Intensive Care Units
- Trial name
- NCT07144878
- Testing
- Parasternal Intercostal Ultrasound and RSBI Assessment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Omega 3, Treatment
Impact of Omega 3 in Treatment of Inappropriate Sinus Tachycardia
This study aimed to evaluate the effect of omega-3 supplementation on heart rate (HR) control and heart rate variability (HRV) in children with inappropriate sinus tachycardia (IST).
- Conditions
- Omega 3, Treatment, Inappropriate Sinus Tachycardia
- Trial name
- NCT07138131
- Testing
- Omega 3, Standard follow-up
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Uveitis
Characteristics of Ankylosing Spondylitis Associated Uveitis
This study aims to understand the clinical characteristics associated with AAU in Egyptian AS patients, and the prognostic factors, in terms of the Corrected Distance Visual Acuity (CDVA).
- Trial name
- uveitis (NCT07113834)
- Testing
- Adalimumab, Systemic corticosteroids
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Benha University
Cesarean Section Complications
Suture Material and C-Section Scar Niches: A Comparative Study
Defective healing of the uterine wound after a Cesarean section (CS) can lead to the formation of a CS niche (CSN). The specific technique used for closure and the type of suture material chosen are often overlooked factors that…
- Trial name
- NCT07101952
- Testing
- Braded Suture material, Multifilament vicryl suture material
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Benha University
Cesarean Section Complications
Surgical Management of Cesarean Scar Ectopic Pregnancy: Hysteroscopy & Laparoscopy Outcomes
The study investigates the feasibility, safety, and outcomes of a simultaneous surgical approach for cesarean scar ectopic pregnancy (CSEP). CSEP is a prevalent and serious form of ectopic pregnancy requiring swift intervention.
- Trial name
- NCT07095647
- Testing
- Hysteroscopy
- Where
- Egypt
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Benha University
Anti-VEGF Therapy
Brolucizumab Versus Aflibercept on Visual and Anatomical Outcomes in Diabetic Macular Edema
This retrospective, comparative cohort study included 38 eyes from 38 patients with center-involving diabetic macular edema (DME), treated at Benha University Hospital.
- Trial name
- Anti-VEGF (NCT07096713)
- Testing
- Intervention 1: Brolucizumab, Intervention 2: Aflibercept
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Benha University
Premature (Early) Ejaculation
On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature Ejaculation
Both Silodosin 4 mg and Dapoxetine 60 mg significantly improved IELT and sexual function scores in primary PE patients. However, Silodosin exhibited a more favorable tolerability profile with fewer side effects, making it a…
- Trial name
- NCT07081659
- Testing
- sildosin 4mg, dapoxetine 60mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Benha University
PCOS
Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility
The study aimed to assess how a 6-month insulin sensitizer therapy impacts insulin resistance, glucose tolerance, and hormonal levels in women with PCOS.
- Trial name
- NCT07058675
- Testing
- Metformin Hydrochloride 500 MG, Myoinositol
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Retinal Detachment
Methotrexate in Retinal Detachment With Proliferative Vitreoretinopathy
The aim of this study is to evaluate the efficacy and safety of intraocular methotrexate (MTX) in preventing and managing proliferative vitreoretinopathy (PVR) in patients undergoing retinal detachment surgery
- Trial name
- Methotrexate (NCT07058337)
- Testing
- parsplana vitrectomy, adjunctive use of Methotrexate
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Acromioclavicular Joint, Acromioclavicular Joint Dislocation
Acute ACJ Dislocation Type (III&VI): CC Ligaments Reconstruction With AC Ligament Reconstruction vs. CC Ligaments Reconstruction With AC Temporary k Wire Fixation
The aim of this study is to compare the clinical and radiographical outcome of patients treated by coracoclavicular ligaments reconstruction associated with acromioclavicular ligament reconstruction versus coracoclavicular…
- Trial name
- NCT07024056
- Testing
- coracoclavicular ligaments reconstruction associated with acromioclavicular ligament reconstruction, coracoclavicular ligaments reconstruction with acromioclavicular temporary k wire fixation
- Volunteers
- 20 people
- Sponsor
- Benha University
Anxiety, Postoperative Pain
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
This prospective randomized controlled study aims to evaluate the anxiolytic effect of preoperative sublingual melatonin and its impact on postoperative pain scores when administered in two different doses to female patients…
- Conditions
- Anxiety, Postoperative Pain, Anesthesia
- Trial name
- NCT06997263
- Testing
- Melatonin 3 mg Sublingual, Melatonin 6 mg Sublingual
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Benha University
Post Partum Hemorrhage
Evaluating Placental Thickness and Thickness of Uterine Muscle at Placenta Attachment in Prediction of Postpartum Blood Loss in Placenta Accreta
Aim of the Work is To determine the significance of the placental thickness and the thickness of the uterine muscle layer at placental attachment in the prediction of postpartum hemorrhage in cases of placenta previa accreta and…
- Trial name
- NCT06351969
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Traumatic Brain Injury, Delirium
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
Traumatic brain injury is a serious and common medical condition that often requires admission to the intensive care unit and the use of mechanical ventilation.
- Conditions
- Traumatic Brain Injury, Delirium, Agitation
- Trial name
- NCT06993194
- Testing
- Haloperidol, Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Benha University
Endophthalmitis Following Cataract Surgery
Compare PPV With and Without Silicone Oil in Managing Postoperative Endophthalmitis
Comparing PPV with and without silicone oil in managing postoperative endophthalmitis
- Trial name
- Endopthalmitis (NCT06990607)
- Testing
- Pars plana Vitrectomy, Silicone Oil
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Preeclampsia Severe, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter in Pre-Eclamptic Parturient Receiving Magnesium Sulfate Combined With Dexmedetomidine
Dexmedetomidine was reported to effectively reduce cerebral metabolism and ICP by decreasing cerebrospinal fluid pressure in patients with cerebral tumors or head injuries that require craniotomy.
- Trial name
- NCT05610774
- Testing
- Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Eyelid Diseases
Lacrimal Deroofing for Epiphora From Punctal Abnormalities
Puncto-canalicular abnormalities, such as obstruction and canaliculitis, are a significant cause of epiphora. They involve proximal lacrimal drainage system.
- Trial name
- NCT04898933
- Testing
- lacrimal deroofing
- Where
- United Arab Emirates
- Volunteers
- 39 people
- Sponsor
- Benha University
Lacrimal Stenosis of Both Eyes
Lacrimal Deroofing for Epiphora
Puncto-canalicular abnormalities, such as obstruction and canaliculitis, are a significant cause of epiphora. They involve proximal lacrimal drainage system.
- Trial name
- NCT06983717
- Testing
- lacrimal deroofing
- Where
- United Arab Emirates
- Volunteers
- 39 people
- Sponsor
- Benha University