Clinical trials: sponsored by Benha University
Haemodynamic Instability
Dexmedetomidine Versus Dexmedetomidine with Ketamine in Mechanically Ventilated ARDS Patients
The goal of this clinical trial study is to compare dexmedetomidine versus the combination of dexmedetomidine with ketamine in hemodynamic changes and sedative effects in ARDS patients who are in need of mechanical ventilation.
- Trial name
- ARDS (NCT05951387)
- Testing
- dexmedetomidine plus ketamine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Magnesium Sulfate - PPHN
Treatment of Persistent Pulmonary Hypertension in Neonates With Nebulized Magnesium Sulfate
we conducted this study to compare between effect of nebulized and intravenous magnesium sulfate (MgSO₄) for better treatment of persistent pulmonary hypertension of neonates with less side effects.
- Trial name
- PPHN (NCT06603766)
- Testing
- IV Magnesium Sulfate, Inhalational magnesium sulfate
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Cardiorenal Syndrome Type 1
Decongestion Guided By VExUS Score Or Lung Ultrasound For Renal Recovery In Patients With Cardiorenal Syndrome Type -1
the goal of this observational study is to evaluate the role of VEXUS score and lung ultrasound to guide decongestive therapy in patients with cardiorenal syndrome type -1.
- Trial name
- NCT06786728
- Testing
- frusemide
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Benha University
Post Operative Pain
Efficient Postoperative Pain Management With Multimodal IV
Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects.
- Trial name
- NCT06661746
- Testing
- Multimodal IV analgesia, epidural analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Pain, Postoperative
External Oblique Intercostal Plane Block Versus Subcostal Transversus Abdominis Plane Block in Supra-umbilical Surgical Incisions
Various newer techniques have been proposed to enhance analgesia in upper abdominal region. The subcostal transverse abdominis plane (SCTAP) block is the deposition of local anesthetic in the transverse abdominis plane inferior…
- Trial name
- NCT05432557
- Testing
- external oblique intercostal plain block (EOIP), subcostal transversus abdominis plane block (SCTAP), control group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Intermittent Exotropia
Symmetric vs Asymmetric BLR Recession in Management of Basic IXT With Ocular Dominance
The study aims to investigate ocular motor and sensory outcomes of two different strategies of lateral rectus recession; symmetric and asymmetric, in management of basic type intermittent exotropia with ocular dominance.
- Trial name
- IXT (NCT05234957)
- Testing
- Bilateral Lateral Rectus Recession
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Benha University
To Assess the Ability of PI to Detect Preload Responsiveness
Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Preload Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume
The primary goal of this study was to assess the ability of PI changes induced by a Vt challenge or fluid challenge test to detect preload responsiveness in critically ill adult patients on mechanical ventilation with low-tidal…
- Trial name
- NCT06673862
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Critically Ill Children, Sepsis
Influencing Factors of Vancomycin Trough Level in Critically Ill Children With Sepsis
The aim of the work will be to measure the vancomycin trough concentration in critically ill children with sepsis in pediatric intensive care unit and its influencing factors.
- Trial name
- NCT06661772
- Testing
- Vancomycin trough concentration method
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Functional Constipation in Children
Is Vitamin D Deficiency Linked to Functional Constipation In Children
Constipation is one of the most common causes of patient visits to pediatric clinics. Prevalence of constipation is estimated between 1.9-27.2% in the USA (Rasquin et al., 2006).
- Trial name
- NCT06657313
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Weaning Failure
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury
The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between…
- Trial name
- NCT06627686
- Testing
- Air way occlusion pressure
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Ulcerative Colitis
Parasitic Infections and Ulcerative Colitis: Combining Anti-parasitic and Immunomodulatory Treatments May Achieve Remission
The study aimed to explore the link between parasitic infections and the severity of ulcerative colitis (UC). 120 UC patients were divided into three groups: those without infection, those with Giardia lamblia infection treated…
- Trial name
- NCT06583863
- Testing
- Echinacea Extract, MetroNIDAZOLE 500 MG Oral Tablet [Flagyl]
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Obstructive Sleep Apnea
Modified Anterior Palatoplasty In Obstructive Sleep Apnea Syndrome
The aim of this study is to evaluate the effectiveness of barbed suture modification of anterior palatoplasty in the treatment of patients with retropalatal mild to moderate obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT04572503
- Testing
- Barbed Suture Modified Anterior Palatoplasty
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Airway Complication of Anesthesia
Comparison Between a Two Person Insertion With Lateral Rotation Technique of LMA and the Classic Technique
The laryngeal Mask Airway was developed by Brain in 1981 and was available for clinical use in the United States by 1992 and has become very popular in routine medicine practice during 10 past years .
- Trial name
- NCT05084612
- Testing
- standard LMA insertion, New technique LMA insertion
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Benha University
ACL Injury
The Difference Between Using Local and General Dexamethasone in Arthroscopic Anterior Cruciate Ligament Repair
Arthroscopic knee injuries, such as the anterior cruciate ligament (ACL) injury, are common and often result in postoperative pain.
- Trial name
- NCT06537518
- Testing
- Dexamethasone injection, Bupivacaine 0.375% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Benha University
COVID-19, Dysglycemia
Can Intensive Insulin Therapy Improve Outcomes of COVID-19 Patients
Evaluation of the reciprocal relation between hyperglycemia/diabetes mellitus (HG/DM) and COVID-19 disease and the effect of mode of insulin therapy; intensive (IIT) or conventional (CIT) on patients' outcomes All patients…
- Trial name
- NCT05441631
- Testing
- Insulin, Subcutaneous Insulin
- Where
- Egypt
- Volunteers
- 436 people
- Sponsor
- Benha University
Primary Open Angle Glaucoma, Glaucoma
The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patients Who Will Undergo Planned Goniectomy for Uncontrolled POAG, Anterior Segment OCT Scan Will Be Used to Evaluate the Anterior Chamber Postoperatively.
Evaluation of anterior segment using anterior segment optical coherence tomography in patients undergoing planned bent angle needle goniectomy procedure for uncontrolled open angle glaucoma.
- Trial name
- NCT06526416
- Testing
- Anterior segment optical coherence tomography
- Volunteers
- 12 people
- Sponsor
- Benha University
Acute Respiratory Distress Syndrome
The Role of Elastic Power in Predicting the Severity and Mortality in Adult Patients With ARDS Due to Pneumonia
the role of elastic power in the prediction of severity and mortality in adults with ARDS secondary to pneumonia
- Trial name
- NCT06477861
- Testing
- calculation of the elastic power of the lung in case of the ARDS and corolating with the severity index of Berline definition of ARDS in respect to mortality and severity
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Post Operative Pain, Acute
Articaine Plus Dexmedetomidine in Supraclavicular Block
Articaine has emerged as a local anesthetic (LA) that produces sensory and motor blockade shorter than bupivacaine and lower in neurotoxicity than lidocaine.
- Trial name
- NCT06423859
- Testing
- Articaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Benha University
Laparoscopic Sleeve Gastrectomy
Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Liver Function
The pandemic of obesity has become a serious issue of public health worldwide as the size of the obese population has almost tripled over the last four decades and continues to riseزThe epidemic of obesity has led to a…
- Trial name
- NCT06423846
- Testing
- Total intravenous anesthesia group, sevoflurane group
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Inguinal Hernia Repair
Buccal Midazolam Versus Intranasal Dexmedetomidine Plus Oral Chloral Hydrate in Inguinal Hernia Repair
Inguinal hernia surgery is one of the most common surgical procedures in early infancy. Preoperative anxiety remains a vexing issue, and it exists in nearly 50% of pediatric patients
- Trial name
- NCT06389318
- Testing
- oral chloral hydrate,intranasal dexmedetomidine and buccal normal saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University