Clinical trials: sponsored by Boston Medical Center
Obesity, Type 2 Diabetes Mellitus
A Study to Examine Changes in GIP Plasma Levels Following Gastric Bypass Surgery in Obese Patients
Obesity is a multinational epidemic. There is evidence that despite educational measures and increased public awareness, the number of obese individuals continues to increase.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NCT00207389
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston Medical Center
Opioid Use Disorder, Neonatal Abstinence Syndrome
RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure
The impact of parental opioid use disorder and other substance use exposure on child welfare and the healthcare system is undeniable.
- Conditions
- Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse
- Trial name
- RESPECT-Plus (NCT02334111)
- Testing
- RESPECT-Plus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Medical Center
Popliteal Artery Aneurysm
Open Versus Endovascular Repair of Popliteal Artery Aneurysm Trial
Weakness in the wall of a blood vessel located behind the knee (popliteal artery) which leads to a swelling of this blood vessel (aneurysm) is one of the most common types of arterial aneurysms.
- Trial name
- OVERPAR (NCT01817660)
- Testing
- Open repair of popliteal artery, Endovascular repair of popliteal artery
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston Medical Center
Low Income Families Basic Social Needs
Addressing Low-Income Families' Basic Social Needs at Pediatric Visits
This research project is aimed to address low-income families' basic social needs (housing, food, employment, education, childcare, utilities) within the context of pediatric primary care.
- Trial name
- NCT01303458
- Testing
- Basic Needs Surveillance (BNS) protocol
- Where
- 9 sites in United States
- Volunteers
- 336 people
- Sponsor
- Boston Medical Center
Sexually Transmitted Infection
Brief Intervention to Reduce STDs in ER Drug Users
The goal of the proposed project is to determine the effectiveness of a brief motivational intervention among Emergency Department (ED) patients who use cocaine and/or heroin to prevent Sexually Transmitted Infections (STIs) and…
- Trial name
- SAFE (NCT01379599)
- Testing
- brief motivation intervention
- Where
- United States
- Volunteers
- 1,030 people
- Sponsor
- Boston Medical Center
Acute Lung Injury, Adult Respiratory Distress Syndrome
Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation
Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) represent a spectrum of clinical syndromes of rapid respiratory system deterioration that are associated with both pulmonary and systemic illness.
- Trial name
- NCT01038531
- Testing
- low-tidal-volume ventilation, APRV
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
Laryngeal Diseases, Chronic Laryngeal Neuropathy
Trial of the Treatment of Chronic Laryngitis With Amitryptiline
The study will compare the effectiveness of amitriptyline versus placebo (inactive medication) in treating chronic laryngitis.
- Trial name
- NCT02434523
- Testing
- Amitriptyline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Medical Center
Mental Competency
Agent-Enhanced Document Explanation
Both the main and sub-studies will investigate how consent forms and other health care documents are explained to patients. The findings will be used to create a computer program that can successfully explain consent and other…
- Trial name
- NCT02668705
- Testing
- Embodied Conversational Agent
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Stress, Psychologic, Pregnancy
Assessing the CenteringPregnancy Planning to Parent Innovation
The investigators propose to evaluate how the CenteringPregnancy curriculum compared with an enhanced curriculum, with the addition of 2 trauma-informed interventions, affects how new parents prepare for parenting and respond to…
- Trial name
- NCT02856711
- Testing
- Trauma-informed group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Parental/Patient Satisfaction
The Impact Of Physician Communication On Family Inpatient Experience
Patient satisfaction is affected by physician communication styles and communication at the bedside. The investigators are conducting a randomized controlled trial involving both providers and families to determine if providers…
- Trial name
- NCT01298791
- Testing
- Sitting, Standing
- Where
- United States
- Sponsor
- Boston Medical Center
Attention Deficit/Hyperactivity Disorder
Comparative Effectiveness Research for Two Medical Home Models for Attention Deficit Hyperactivity Disorder
The purpose of this study is to compare the effectiveness of two care models on ADHD outcomes: one, a model of basic care management and structured communication with specialists, consistent with conventional descriptions of a…
- Trial name
- NCT01275378
- Testing
- Collaborative Care Plus, Traditional Collaborative Care
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Maternal Depression
Problem Solving Education and Neonatal Intensive Care Unit (NICU) Mothers
Premature infants are born at substantial risk for poor health and developmental outcomes, which commonly include hearing and vision problems, developmental delays, and poor school performance.
- Trial name
- Project Solve (NCT01214967)
- Testing
- Problem Solving Education
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Boston Medical Center
HIV Infection, Alcohol Use
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort
The purpose of this study is to expand and continue a cohort of HIV-infected adults to establish the longitudinal Boston ARCH Cohort of 250 HIV-infected men and women with current substance dependence or ever injection drug use…
- Conditions
- HIV Infection, Alcohol Use, Bone Disease, Substance-Related Disorders
- Trial name
- NCT01740115
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Depression
Preventing Maternal Depression In Head Start
Maternal depression disproportionately affects low-income and minority women, and has profound negative impacts on their children.
- Trial name
- NCT01298804
- Testing
- Problem Solving Education and Activated Referral to Care
- Where
- 2 sites in United States
- Volunteers
- 230 people
- Sponsor
- Boston Medical Center
Sepsis
Regression Discontinuity Design to Evaluate of Drotrecogin Alpha Effectiveness
Many health care interventions and medications found to have benefits ("efficacy") in experimental, tightly-controlled, human research trials are later found to lack real-world health benefits ("effectiveness").
- Trial name
- NCT02843685
- Testing
- Drotrecogin alfa activated
- Where
- United States
- Volunteers
- 12,492 people
- Sponsor
- Boston Medical Center
Recurrent Low Back Pain
Yoga vs. Education for Veterans With Chronic Low Back Pain
Chronic low back pain (cLBP) is the most common pain condition in the military, causing substantial physical and psychological suffering, reduction in force readiness, and high economic cost.
- Trial name
- NCT02224183
- Testing
- Education, Yoga
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Boston Medical Center
Body Weight
Weight Management Among Breast Cancer Survivors
The long-term goal of this research is to develop, evaluate and implement effective mHealth technology interventions that improve cancer management outcomes by changing lifestyle behaviors among urban health- disparity facing…
- Trial name
- NCT02387671
- Testing
- Device: FitBit Flex wrist band, Device: FitBit Aria weight scale, Diet Intake Messages
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Cancer, Thyroid
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Trial name
- NCT01401855
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Hypertension
Interactive Multirisk-Factor Intervention for Hypertension (HTN) Blacks
The aim of this study is to assess the efficacy of Telephone-Linked_Care for Hypertension Regimen Adherence in an African American population (TLC-HTN-AA).
- Trial name
- NCT00207194
- Testing
- Automated Telephone Program, Health Behavior Education
- Where
- United States
- Volunteers
- 337 people
- Sponsor
- Boston Medical Center
Breast Cancer, Cervical Cancer
Patient Navigation in the Safety Net:CONNECTeDD
The Boston University Medical Center, funded by the National Cancer Institutes will train health workers at six of its affiliated Community Health Centers to guide patients through the cancer care system.
- Trial name
- NCT00613275
- Testing
- patient Navigation
- Where
- United States
- Volunteers
- 4,038 people
- Sponsor
- Boston Medical Center