Clinical trials: sponsored by Boston Medical Center
Amyloidosis
Assessment of Minimal Residual Disease (MRD) After Antineoplastic Treatment in Patients With AL Amyloidosis
In this study, the investigators seek to evaluate bone marrow and blood samples and treatment responses to see if Minimal Residual Disease (MRD) can be used as a predictive method of response to treatment in amyloidosis.
- Trial name
- MRD (NCT02716103)
- Testing
- blood collection, bone marrow collection
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston Medical Center
Cancer
Patient Navigation in Cancer Survivorship at a Safety Net Institution
This study seeks to enroll patients receiving a Survivorship Care Plan following curative therapy for cancer. Participants will be randomly assigned to receive usual care or to be followed by a Patient Navigator as part of their…
- Trial name
- NCT03271099
- Testing
- Navigator
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Boston Medical Center
HIV Infections, Stigmatization
Stigma, Risk Behaviors and Health Care Among HIV-infected Russian People Who Inject Drugs
This study is a randomized controlled trial (RCT) among 100 HIV-positive people with injection drug use, which aims to test the feasibility of the SCRIPT intervention and evaluate its effectiveness on the reduction of…
- Conditions
- HIV Infections, Stigmatization, Substance Use
- Trial name
- SCRIPT (NCT03695393)
- Testing
- ACT Therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Boston Medical Center
Metabolic Syndrome, Obesity
Virtual Weight Management Shared Medical Visit
Culinary medicine has emerged which provides the practical application of nutrition education through experiential learning. Studies have shown that patients with metabolic syndrome who underwent a series of classes that featured…
- Trial name
- NCT04784338
- Testing
- Virtual shared medical visit, Nutritional classes
- Sponsor
- Boston Medical Center
Post Operative Complications, Pneumonia
Inpatient ICOUGH RECOVERY App Version 2.0
This pilot study will evaluate how well version 2 of the ICOUGH app, a bed-side mobile app increases patients' adherence to a postoperative protocol called ICOUGH.
- Trial name
- ICOUGH (NCT03599037)
- Testing
- ICOUGH Recovery App v2.0
- Where
- United States
- Sponsor
- Boston Medical Center
Alcohol Use Disorder
Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03271528
- Testing
- Lacosamide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Medical Center
Diabetic Foot, Diabetic Foot Ulcer
Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers
The key purpose of this study is to determine and understand the safety and effectiveness of blue light phototherapy in the treatment and healing of infected diabetic wounds, as well as determining if this treatment is capable of…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Diabetes, Diabetes Mellitus
- Trial name
- NCT04285710
- Testing
- Phototherapy, Debridement Surgery and Wound Dressing
- Where
- United States
- Sponsor
- Boston Medical Center
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
AL Amyloidosis
Daratumumab for the Treatment of Patients With AL Amyloidosis
Participants with AL Amyloidosis will receive the drug daratumumab by IV infusion once weekly for two months, then every 2 weeks for four months, then once each month.
- Trial name
- NCT02841033
- Testing
- daratumumab
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Vascular Access Complication, Ultrasound Therapy; Complications
Superior Venous Access, Midline vs Ultrasound IVs
Obtaining intravenous access (IVA) is the most common procedure performed in the emergency department (ED). Placement of IVA allows for blood work and delivery of intravenous fluids and medications.
- Trial name
- NCT03440944
- Testing
- Ultrasound Guided Peripheral IV Catheter, Midline Catheter
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Housing Instability, High Emergency Department Utilization
Housing Prescriptions as Health Care
Housing Prescriptions as Health Care is a research project studying the effects of an innovative intervention that combines services across the health, housing, social and legal service sectors in order to improve housing…
- Conditions
- Housing Instability, High Emergency Department Utilization, Medical Complexity
- Trial name
- NCT02816294
- Testing
- Housing Prescription
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Empathy
Small Moments Big Impact (SMBI)
Empathy is defined as sensitivity to the needs of others.Maternal empathy, or a mother's sensitivity to the needs of her child, is critical for healthy child development ,Small Moments, Big Impact: Supporting Maternal Empathy by…
- Trial name
- SMBI (NCT03887832)
- Testing
- SMBI digital app, media package, standard newborn and infant care
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Healthcare Utilization
THRIVE+ Pharmacy Liaison-Patient Navigation Intervention
This is a pragmatic comparative effectiveness trial (n=364) to compare two screening and referral program models to address health-related social needs (HRSN) among the intermediate risk population of Boston Accountable Care…
- Trial name
- THRIVE+ (NCT03919084)
- Testing
- THRIVE screening and referral, Pharmacy Care Program services, Patient Navigation Services
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Alcohol Drinking
Calibration Study of a Blood Alcohol Level Smart Watch
This trial is designed to test the accuracy of a wristwatch blood alcohol level monitor relative to alcohol breath testing. An established human laboratory self-administration procedure will be followed.
- Trial name
- NCT03574181
- Testing
- Smartwatch to measure Blood Alcohol Level (BAL)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Rhinoplasty
Betadine Effect on Nasal Mucosa Cilia
The goal of the proposed study is to identify PVP-I at 1.25% as an appropriate intranasal topical preparation for patients undergoing rhinoplasty with no effect on the nasal mucosa cilia (NMC) or olfaction using the saccharin…
- Trial name
- NCT04457765
- Testing
- Povidone-Iodine (PVP-I)
- Where
- United States
- Sponsor
- Boston Medical Center
Atrial Fibrillation, Risk Factors
Secondary Prevention of Atrial Fibrilation
Atrial fibrillation (AF) is the most common arrhythmia affecting over 3 million Americans and about 33.5 million individuals globally. The lifetime risk of developing AF is 1 in 4 for adults over age 40 years.
- Conditions
- Atrial Fibrillation, Risk Factors, Risk Reduction Behavior
- Trial name
- NCT03259893
- Testing
- AliveCor mobile ECG cardiac monitor, AF Program, Standard of care
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Boston Medical Center
HIV Infection, Alcohol Use
Alcohol's Impact on Inflammatory Markers in HIV Disease - Russia ARCH Cohort
The purpose of this study is to assess the longitudinal association between alcohol consumption and biomarkers of microbial translocation (sCD14) and inflammation/altered coagulation (IL-6/D-dimer); to establish a cohort of…
- Trial name
- NCT01614626
- Where
- Russia
- Volunteers
- 351 people
- Sponsor
- Boston Medical Center
HIV Infection, Alcohol Use
Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV)
This study is a randomized controlled trial (RCT) to compare the effects of varenicline, cytisine, and nicotine replacement therapy (NRT) to reduce: 1) alcohol use and craving, 2) smoking; and 3) inflammation and risk for…
- Conditions
- HIV Infection, Alcohol Use, Smoking
- Trial name
- St PETER HIV (NCT02797587)
- Testing
- Varenicline, Cytisine, Nicotine Replacement Therapy
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Boston Medical Center
HIV, Hepatitis C
Integrating HCV and HIV Screening During the Era of HIV Antigen Testing
The objective of this proposal is to develop an optimal testing strategy for HCV and HIV in high prevalence settings, such as detoxification centers with a large proportion of young injection drug users.
- Trial name
- NCT02869776
- Testing
- Questionnaire, Rapid finger stick, Venipuncture
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Medical Center
Depression Chronic, Advanced Cancer
Sophie Pilot Implementation and Assessment
Evidence-based interventions using cognitive behavioral therapy (CBT) and self-management education have been demonstrated to effectively treat symptoms of depression and improve the quality of life in populations with chronic…
- Conditions
- Depression Chronic, Advanced Cancer, Anxiety
- Trial name
- NCT03904342
- Testing
- Sophie CBT System, iHope CBT
- Sponsor
- Boston Medical Center