Clinical trials: sponsored by Boston University
Vitamin D Deficiency, Vitamin D Insufficiency
Solius UV Light Source in Improving Serum Levels of 25-hydroxyvitamin D
This is a feasibility interventional study seeking to determine the safety and efficacy of the Solius Photobiologic System in increasing the serum levels of 25(OH)D in a vitamin D deficient/insufficient adult population.
- Trial name
- NCT04865432
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston University
Borderline Personality Disorder
Isolating Mechanisms in the Treatment of Borderline Personality Disorder
Borderline personality disorder (BPD) is a commonly occurring, severe, and costly condition that interferes greatly with quality of life.
- Trial name
- NCT03408860
- Testing
- Countering Emotional Behaviors Module from Unified Protocol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston University Charles River Campus
Insomnia
Reducing Health Disparities for Black Women in the Treatment of Insomnia
Black women are at a higher risk of developing insomnia than other women and insomnia has profound adverse physical and psychological health consequences.
- Trial name
- NCT03613519
- Testing
- SHUTi, modified SHUTi (i.e., SHUTi-BWHS), Patient education
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- Boston University
Sexual Behavior
Young Men and Media Study
Adolescent sexual minority males (ASMM) continue to account for a disproportionate number of HIV infections in the United States. Racial and ethnic minority populations are particularly affected.
- Trial name
- NCT04109443
- Testing
- Young Men & Media Program, Available websites on safe sex and preventing STIs
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Schizophrenia, Schizoaffective Disorder
Motivation and Skills Support (MASS)
Social impairment contributes to more severe symptoms, higher rates of hospitalization, and increased disability in persons with schizophrenia.
- Trial name
- NCT03404219
- Testing
- Motivation and Skills Support (MASS)
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Boston University Charles River Campus
Tobacco Smoking
Cognitive and Emotional Skills to Aid Smoking Prevention
The purpose of the current proposal is to investigate the extent to which interventions designed to improve cognitive (working memory) and emotional (distress tolerance) regulatory processes enhance the effectiveness of standard…
- Trial name
- DOAN (NCT03058991)
- Testing
- Distress Tolerance Intervention, Working Memory Intervention, Control Informational Intervention
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Heavy Drinking, Alcohol Dependence
Alcohol Disorder hOsPital Treatment Trial
The specific aims of this pragmatic randomized controlled trial are to compare initiating injectable extended release naltrexone (XR-NTX) or oral naltrexone (PO-NTX) at the time of discharge from a medical hospitalization for…
- Conditions
- Heavy Drinking, Alcohol Dependence, Alcohol Use Disorder
- Trial name
- ADOPT (NCT02478489)
- Testing
- Oral naltrexone (PO-NTX), Extended-release injectable naltrexone (XR-NTX)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Boston University
Smoking, Cessation
Usability Study of a Smoking Cessation Intervention During a Dental Cleaning
The goal of this usability study is to pilot test the recruitment procedures, data acquisition methods, and text message program integration required to support the planning of a future clinical trial.
- Trial name
- NCT04247061
- Testing
- Educational video, Text-message program
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston University
Alcohol; Harmful Use, Sex, Unsafe
MI With Text Messaging to Reduce Sexual Risk and Hazardous Drinking Among MSM
This is a small pilot study to provide effect size estimates for a brief intervention designed to reduce hazardous drinking and sexual risk behavior among men who have sex with men.
- Trial name
- MI&TXT4MSM (NCT03755661)
- Testing
- MI&TXT4MSM
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Heavy Drinking and Sexual Risk Behavior
Alcohol and Sex Risk Intervention for MSM Supplement
Open pilot trial to test the feasibility and efficacy of a brief intervention with text messaging to reduce sexual risk behavior and heavy drinking among MSM
- Trial name
- NCT03522948
- Testing
- Brief intervention with text messaging to reduce sexual risk and heavy drinking among MSM
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Pulmonary Hypertension, Sickle Cell Disease
Macitentan in Pulmonary Hypertension of Sickle Cell Disease
This is a pilot study to assess the safety and efficacy of macitentan in patients with pulmonary hypertension of sickle cell disease. This study will enroll approximately 10 subjects.
- Trial name
- MENSCH (NCT02651272)
- Testing
- macitentan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston University
Alcoholic Intoxication, Neurobehavioral Manifestations
Residual Effects of Intoxication on Student Performance
The primary goal of the study is to assess the residual effects of heavy drinking on academic performance. The investigators will also explore whether these effects differ by family history of alcohol abuse and hangover symptoms…
- Trial name
- NCT00183170
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Boston University
Sepsis
Zambia Chlorhexidine Application Trial
This will be a cluster-randomized controlled trial to assess whether washing the umbilical cord with a disinfectant (4% chlorhexidine) helps to reduce neonatal deaths in Zambia when compared to the current standard of care, dry…
- Trial name
- ZamCAT (NCT01241318)
- Testing
- Chlorhexidine gluconate (4%), Dry cord care
- Where
- Zambia
- Volunteers
- 77,535 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV/AIDS, Chronic HIV Infection
Life Plans Intervention Study
The mass provision of HIV treatment in rural KwaZulu-Natal, South Africa has raised adult life expectancy by 18 years since 2003.
- Conditions
- HIV/AIDS, Chronic HIV Infection, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03215901
- Testing
- A Beautiful Future Video, Active Control Video
- Where
- South Africa
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Boston University
Mental Disorders
Testing Effectiveness of a Peer-Led Intervention to Enhance Community Integration
We are conducting a randomized clinical trial (RCT) comparing the 10-week peer-led Photovoice program to services as usual (SAU) at a large publicly funded community mental health agency in Massachusetts.
- Trial name
- Photovoice (NCT02508480)
- Testing
- Photovoice, Enhanced Control
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Boston University Charles River Campus
Chronic Pain, Alcohol Use, Unspecified
Internet-based Videoconferencing to Address Alcohol Use and Pain
This research seeks to develop a novel, integrated behavioral approach to reduce heavy drinking and chronic pain among patients in HIV-care delivered via internet-based videoconferencing.
- Trial name
- NCT03982433
- Testing
- Motivation and Cognitive Behavioral Management for Alcohol and Pain
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston University Charles River Campus
Transition-age Youth, Developmental Disabilities
Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications)
The purpose of this study is to determine the extent to which Project TEAM (Teens making Environment and Activity Modifications) is an effective, socially valid, and feasible intervention that prepares youth with developmental…
- Conditions
- Transition-age Youth, Developmental Disabilities, Cerebral Palsy, Autism
- Trial name
- ProjectTEAM (NCT02714868)
- Testing
- Project TEAM, Matched Comparison
- Volunteers
- 82 people
- Sponsor
- Boston University Charles River Campus
Major Depressive Disorder
Efficacy of Adjunctive Exercise for the Behavioral Treatment of Major Depression
Major depressive disorder (MDD) is the leading cause of disability in the developed world and is associated with lost productivity, increased health care utilization, and mortality.
- Trial name
- NCT02176408
- Testing
- Behavioral Activation, Exercise Intervention, Stretching Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Boston University Charles River Campus
Substance Dependence
Stress, Distress Intolerance, and Drug Dependence
This study is designed to evaluate the relative efficacy of a novel treatment (CBT-IC) versus a standard individual drug-counseling treatment.
- Trial name
- NCT00430482
- Testing
- Cognitive Behavioral Therapy, Individual Counseling
- Where
- 2 sites in United States
- Volunteers
- 133 people
- Sponsor
- Boston University Charles River Campus
Social Anxiety Disorder
Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
This study will assess the effectiveness of D-cycloserine combined with cognitive-behavior therapy in treating people with social anxiety disorder.
- Trial name
- NCT00515879
- Testing
- D-cycloserine, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Boston University Charles River Campus