Clinical trials: sponsored by Boston University
Arthritis
A Modified Rehabilitation Intervention for Working Persons With Arthritis
The purpose of this study is to explore the effects of a brief vocational rehabilitation intervention on individuals with arthritis who are concerned about their ability to remain employed.
- Trial name
- Work It (NCT01387100)
- Testing
- Vocational Rehabilitation Intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Boston University Charles River Campus
Down Syndrome
Harness-based Mobility Intervention for Infants With Down Syndrome
The emergence of crawling and walking is significantly delayed in infants with Down syndrome (DS), but the development of independent mobility provides infants with new opportunities for exploring the environment and interacting…
- Trial name
- NCT06219863
- Testing
- Body weight supported harness
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Boston University Charles River Campus
Systemic Scleroderma, Diffuse Cutaneous Scleroderma
Diffuse Cutaneous Scleroderma (DSSc) SFDI Study
Scleroderma (SSc) is an autoimmune disease characterized by fibrosis (or collagen deposition) of the skin and internal organs. The extent of skin fibrosis is an important predictor of internal organ complications and increased…
- Trial name
- SFDI (NCT07090226)
- Testing
- Spatial-frequency domain imaging (SFDI)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Boston University
Heavy Drinking and Sexual Risk Behavior
Alcohol and Sex Risk mHealth-Enhanced Brief Intervention for BLMSM
Randomized controlled pilot trial to test the feasibility and efficacy of a brief intervention with app-based messaging to reduce sexual risk behavior and heavy drinking among Black/African American and Hispanic/Latino MSM.
- Trial name
- NCT04821427
- Testing
- Brief mhealth intervention + mobile messaging to reduce sexual risk behavior and heavy drinking
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
OCD
Neuromodulation for a Novel OCD Biomarker and Treatment
Although multiple treatments for OCD exist, slow symptom decrease, high remission, and significant side effects for some OCD patients limit their efficacy.
- Trial name
- NCT05994053
- Testing
- high definition transcranial alternating current stimulation
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Social Anxiety Disorder
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
The purpose of this clinical trial is to answer the question: can the investigators predict which adults with social anxiety disorder (SAD) will successfully respond to treatment? To answer this question, the investigators plan…
- Trial name
- NCT05683223
- Testing
- Group CBT for Social Anxiety Disorder, Sertraline, Individual CBT for Social Anxiety Disorder
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Aging, Noninvasive Brain Stimulation
Memory Enhancement in Aging With Closed-Loop tACS
This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen…
- Conditions
- Aging, Noninvasive Brain Stimulation, Memory
- Trial name
- NCT07722598
- Testing
- Peak Frequency, Phase Lag, Peak Frequency + Phase Lag
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Memory Disorders in Old Age
Improving Working Memory in Older Adults
The research program will evaluate the theoretical claim that age-related memory and cognitive decline in humans result from the inefficient orchestration of rhythmic activity within large-scale cortical networks.
- Trial name
- NCT04362696
- Testing
- High definition transcranial electrical current stimulation
- Where
- United States
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Aging, Noninvasive Brain Stimulation
Memory Enhancement in Aging With Optimal Dosing
This project optimizes high-resolution transcranial Alternating Current Stimulation (tACS) to improve memory in healthy older adults, advancing drug-free approaches for Alzheimer's disease and related dementia (ADRD).
- Conditions
- Aging, Noninvasive Brain Stimulation, Memory
- Trial name
- NCT07461584
- Testing
- 1-day patterned tACS, 3-day patterned tACS, 5-day patterned tACS
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Panic Disorder, Agoraphobia
Effectiveness of Intensive Cognitive Behavioral Therapy in Treating Adolescent Panic Disorder and Agoraphobia
This study will evaluate the effectiveness of intensive cognitive behavioral therapy in treating adolescents with panic disorder with agoraphobia.
- Trial name
- NCT00576719
- Testing
- Intensive panic control treatment without parent involvement, Intensive panic control treatment with parent involvement, Waitlist control
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Boston University Charles River Campus
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Accidental Falls
Training Improves Balance Control
The purpose of this study was to evaluate the effect of a group-based functional and specific balance training program on balance function in healthy older adults.
- Trial name
- NCT01547988
- Testing
- Balance Training Intervention
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Panic Disorder
Effectiveness of Cognitive Behavioral Therapy With Panic Control Treatment for Adolescents With Panic Disorder
This study will evaluate the effectiveness of cognitive behavioral therapy with a panic control treatment component in treating adolescents with panic disorder.
- Trial name
- NCT00705380
- Testing
- Cognitive behavioral therapy (CBT) with panic control treatment (PCT) for adolescents, Waitlist control
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Boston University Charles River Campus
Childhood Depression
Neural Mechanisms of Family-Focused Treatment for Youth Depression
The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused…
- Trial name
- NCT06289010
- Testing
- Family-Focused Treatment for Childhood-Depression (FFT-CD)
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Mental Health, Work Related Stress
Testing the Effectiveness of Mainstream Management Tools to Increase Organizational Commitment and Job Satisfaction and Decrease Turnover Among Peer Providers
The role of peer support specialists (PSS) has burgeoned in the mental health field. Peer support specialists are individuals with a psychiatric condition who are in recovery and who are employed to provide various kinds of…
- Trial name
- NCT04398407
- Testing
- Coaching and Advancement for Peer Providers (CAPP)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Boston University Charles River Campus
Alcohol Drinking, Sex, Unsafe
Alcohol and "Heat of the Moment" Sexual Decision Making
HIV transmission remains a significant public health concern, especially among men who have sex with men (MSM). Condomless anal intercourse (CAI) continues to be the major route of transmission for MSM.
- Conditions
- Alcohol Drinking, Sex, Unsafe, Hiv
- Trial name
- NCT05729256
- Testing
- Self-Regulation Intervention, Brief Advice and Information
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Knee Osteoarthritis
Improving Walking Quality and Quantity in Osteoarthritis (IWALQQ-OA)
This study evaluates the feasibility of a mindful walking intervention for management of knee osteoarthritis. Participants will be randomly assigned to receive one of two interventions i.e.
- Trial name
- IWALQQ-OA (NCT03064139)
- Testing
- MCG, SCG
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Boston University Charles River Campus
Exercise
Assessment of the Predictors and Moderators of Behavior Change
The current study aims to investigate two potential interventions (i.e., cognitive dissonance and action planning) for inducing behavior change for behaviors important to college students-studying and exercise.
- Trial name
- ABC (NCT03139643)
- Testing
- Cognitive Dissonance, Action Planning, Reflection (Control Condition)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Eating Disorders
A Novel Motivational Ecological Momentary Intervention for Anorexia Nervosa
The aim of this study is to pilot an innovative motivational text-message intervention for individuals with anorexia nervosa and subthreshold anorexia nervosa.
- Trial name
- NCT02076854
- Testing
- Text-Message Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston University Charles River Campus
Physical Activity
Enhance Physical Activity in Low-income Black and Hispanic Adults
The present study aims to test the efficacy of a multi-level telehealth intervention to Enhance Physical Activity (EPA) in 300 low-income Black and Hispanic/Latino adults.
- Trial name
- NCT05702346
- Testing
- Enhance Physical Activity (EPA)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus