Clinical trials: sponsored by Boston University
Superficial Basal Cell Carcinoma, Squamous Cell Carcinoma in Situ
5-Fluorouracil and Calcipotriene for Treatment of Low Grade Skin Cancer
The investigators will compare the application of two different creams for the treatment of low-risk skin cancers-superficial basal cell carcinoma (sBCC) and squamous cell carcinoma in situ (SCCis).
- Trial name
- NCT05381597
- Testing
- Combination cream of 5-fluorouracil and calcipotriene, 5-fluorouracil cream
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston University
HIV
Gathering Records to Evaluate Antiretroviral Treatment-South Africa
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04149782)
- Testing
- Routine medical record data collection
- Where
- South Africa
- Volunteers
- 7,000,000 people
- Sponsor
- Boston University
HIV
Gathering Records to Evaluate Antiretroviral Treatment-Zambia (GREAT )
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04158882)
- Testing
- Routine medical record data collection
- Where
- Zambia
- Volunteers
- 1,200,000 people
- Sponsor
- Boston University
Breast Cancer, Gynecologic Cancer
Stress Management Intervention Among Breast and Gynecologic Cancer Patients in Viet Nam
Psychological distress is common among Vietnamese cancer patients but often underestimated and not detected by professionals due to lack of time and overload of clinical work.
- Trial name
- NCT06398067
- Testing
- Vietnamese Self-Help Plus (vSH+), 'Doing What Matters in Times of Stress' (DWM) Guide
- Where
- 6 sites in Vietnam
- Volunteers
- 285 people
- Sponsor
- Boston University
HIV
Gathering Records to Evaluate Antiretroviral Treatment-Malawi ( GREAT )
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04158895)
- Testing
- Routine medical record data collection
- Where
- Malawi
- Volunteers
- 1,000,000 people
- Sponsor
- Boston University
Stroke
Neurostimulation Exosuit Augmented Training (NEAT) in the Clinic
The primary goal of this study is to understand the feasibility and rehabilitative effects of a Neurostimulation Exosuit Augmented Training (NEAT) program designed to provide high-intensity gait training in progressively…
- Trial name
- NCT07218107
- Testing
- Neurostimulation Exosuit
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Boston University Charles River Campus
Stroke
Effects of an Overground Propulsion Neuroprosthesis in Community-dwelling Individuals After Stroke
This interventional study evaluates the effects of an overground propulsion neuroprosthesis that delivers adaptive neurostimulation assistance to the paretic plantarflexors and dorsiflexors of people post-stroke.
- Trial name
- NCT06459401
- Testing
- Propulsion Neuroprosthesis
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Boston University Charles River Campus
Stroke
Personalized Post-Stroke Gait Rehabilitation Interventions
The objective of this study is to understand whether certain post-stroke patient subsets, identified from clinical, biomechanical, and neuromuscular characteristics, preferentially respond to different walking rehabilitation…
- Trial name
- NCT07212608
- Testing
- Soft robotic exosuit, Propulsion neuroprosthesis
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston University Charles River Campus
Alcohol Drinking, Chronic Pain
Mobile App-based Approach for Reducing Pain and Hazardous Drinking: a Pilot Study
Chronic pain and heavy drinking are common co-occurring conditions among patients presenting to primary care settings. Given their impact on functioning and medical outcomes, there would be considerable benefit to developing an…
- Trial name
- NCT06281821
- Testing
- mhealth-pc
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease, Mood
The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease
This online study aims to explore the benefits of nature for mood and cognition in persons with and without Parkinson's disease.
- Conditions
- Parkinson Disease, Mood, Cognition
- Trial name
- NCT06483126
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Parkinson's Disease, Perception
Perception in Parkinson's Disease
The investigators plan to examine the relation of perceptual variables-basic vision, unusual perceptual experiences(including but not limited to visual hallucinations)-to relevant functional variables such as cognition, mood, and…
- Conditions
- Parkinson's Disease, Perception, Visual Hallucination
- Trial name
- NCT05483036
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Boston University Charles River Campus
HIV
Integrating U=U Into HIV Counseling in South Africa
The near-elimination of HIV transmission with antiretroviral therapy (ART) has provided the world with a clear path to end the HIV epidemic through the mass provision of ART at diagnosis, i.e. test-and-treat.
- Trial name
- INTUIT-SA (NCT04504357)
- Testing
- Tablet based U=U app, Text messages
- Where
- 3 sites in South Africa
- Volunteers
- 135 people
- Sponsor
- Boston University
Dietary Habits
Evaluation of an Artificial Intelligence-Assisted, Image-Based Dietary Assessment Tool in the Framingham Heart Study
Assessment of dietary intake in large, free-living populations is inherently challenging due to the complex nature of human diet.
- Trial name
- NCT06455111
- Testing
- Keenoa, ASA24
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Boston University
Adolescent Behavior, Mental Health Wellness 1
Leadership, Engagement, and Youth Action Program With Mindfulness (LEAP)
The current study tests the feasibility and effectiveness of a youth intervention designed to provide meaningful leadership opportunities through the acquisition of leadership skills as well as mindfulness practice, LEAP…
- Trial name
- NCT06227403
- Testing
- Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Amped-PD: Amplifying Physical Activity Through Music in Parkinson Disease
Regular, habitual exercise is a critical component of the long-term management of Parkinson disease (PD). However, PD-specific motor (e.g. slow and diminished movements, variable step timing) and non-motor (e.g.
- Trial name
- Amped-PD (NCT05421624)
- Testing
- Digital music therapeutic, Active-Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston University Charles River Campus
Alcohol Use Disorder, Anxiety Disorders
Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders
Almost 18 million US adults have alcohol use disorders (AUD), with one third of these individuals also diagnosed with anxiety disorders (AXD).
- Trial name
- NCT03230006
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders, Take Control
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston University Charles River Campus
Parkinson Disease
Walking and mHealth to Increase Participation in Parkinson Disease
Identifying effective ways to improve function, slow decline and reduce disability is a high priority for people living with Parkinson disease and other chronic conditions.
- Trial name
- WHIPPD (NCT03517371)
- Testing
- mHealth delivered exercise program, Exercise only
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Boston University Charles River Campus
Cardiovascular Diseases
Second eFramngham Heart Study
In the electronic Framingham Heart Study (eFHS), the investigators developed and deployed a mobile app to collect cardiovascular risk factors and event data and test them against cardiovascular data collected in the Framingham…
- Trial name
- eFHS-2 (NCT04752657)
- Testing
- Delayed administration of survey modules, Regular administration of survey modules
- Where
- United States
- Volunteers
- 492 people
- Sponsor
- Boston University
Atopic Dermatitis
Improvement In Scratch Behavior And Sleep In Patients With Atopic Dermatitis
This single blind study is to primarily evaluate wearable devices and Observer Reported Itch Assessment in children to assess reduction of itch and night-time scratch in response to Crisaborole treatment vs.
- Trial name
- PAD (NCT05200403)
- Testing
- Crisaborole 2%, Vehicle treatment, Accelerometry device for children
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston University
Siblings, Childhood Cancer
SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer
This study aims to address barriers to psychosocial care for siblings of children with cancer by piloting a group-based telehealth program for adolescent siblings of youth with cancer.
- Conditions
- Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
- Trial name
- R03 CA259898 (NCT04889755)
- Testing
- SibACCESS
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus