Clinical trials: sponsored by Brown University
Smoking Cessation, Alcohol Drinking
Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation
The overall objective of this project is to develop and pilot-test a web-based smoking cessation program that specifically addresses heavy drinking (HD).
- Trial name
- NCT03068611
- Testing
- Standard Web-based Smoking Cessation, Alcohol-focused Web-Based Smoking Cessation
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Brown University
Hazardous Drinking, HIV
Brief Alcohol Intervention for HIV-Infected Men Who Have Sex With Men (MSM) in a Primary Care Setting
This is a randomized clinical trial to examine the effects of a brief counseling intervention for heavy drinking HIV-infected men who have sex with men compared to HIV care as usual.
- Trial name
- NCT01328743
- Testing
- Brief alcohol intervention
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Brown University
Exercise
A Comparison of Exercise Beliefs to Same-day Exercise Behavior
Regular aerobic exercise is associated with reduced risk of multiple cancers, yet the majority of adults are inactive. Across health behavior theories, the expectations people have about the outcomes of exercise influence their…
- Trial name
- NCT03415542
- Testing
- Exercise Promotion
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Consumption, Alcohol Abuse
Reducing Hazardous Alcohol Use in Social Networks Using Targeted Intervention
Alcohol use is almost ubiquitous on college campuses and first-year students are at particularly high risk of alcohol-related harm when they first make the transition to college.
- Trial name
- NCT02895984
- Testing
- Single-session alcohol intervention (BMI)
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- Brown University
Calculi
The Effect of Vitamin D Repletion on Kidney Stone Risk
Examine the effect of nutritional vitamin D repletion on urinary calcium excretion and kidney stone burden in calcium kidney stone formers
- Trial name
- NCT02752841
- Testing
- Nutritional vitamin D repletion and maintenance
- Volunteers
- 20 people
- Sponsor
- Brown University
Mobile Health Intervention to Promote HIV Self-testing
mHealth and HIV Self-testing
The investigators will pilot test an intervention to use a mobile application ("app") to improve HIV self-testing (HST) with high-risk men in China.
- Trial name
- NCT03569462
- Testing
- Mobile "WeChat" intervention, Control condition
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brown University
Diet Habit, Physical Activity
Mindfulness-Based College: Stage 1
Mindfulness interventions are increasingly offered to undergraduate students at universities world-wide, however the evidence base is very limited.
- Conditions
- Diet Habit, Physical Activity, Sleep, Loneliness
- Trial name
- MB-College (NCT03124446)
- Testing
- Mindfulness-Based College, Enhanced Usual Care Control
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV Infections, Alcohol Abuse
Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing
The overall objective of this research is to use both qualitative and quantitative data to inform the development of a technology-based intervention for heavy drinking and sexual risk behavior among men who have sex with men…
- Trial name
- NCT03435783
- Testing
- Brief Electronic Intervention, Attention-Matched Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brown University
HIV
Evaluating a Real-Time, Remote Monitoring System for Home-Based HIV Testing
This study explores whether offering follow-up counseling and referral over the phone after using a home-based HIV test increases rates of ever and repeat testing, compared with home-based testing with no follow-up (HBST alone)…
- Trial name
- (eTEST) (NCT02876926)
- Testing
- "Smart" home-based test for HIV, Home-based testing only, Reminder letters for clinic-based testing
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Brown University
Breast Cancer
Trial of Chemotherapy and Avastin as Treatment for Women With Breast Cancer at High Risk for Relapse
Women with breast cancer who are not eligible for breast conserving surgery or who have node-involvement are sometimes treated with chemotherapy up front, in hopes of allowing for a woman to keep her breast and decreasing the…
- Trial name
- NCT00462865
- Testing
- Gemcitabine and Capecitabine and Avastin
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- Brown University
Suicidal Ideation, Suicide, Attempted
Skills to Enhance Positive Affect in Suicidal Adolescents
The prevalence of suicidal behaviors in adolescents remains unacceptably high and is a significant public health concern. The investigators propose a new treatment approach in which skills to increase positive emotions are taught…
- Trial name
- STEP (NCT02130583)
- Testing
- Positive Affect Skills Training, Treatment as Usual
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Brown University
Nicotine Dependence
Incentives to Promote Smoking Cessation in Low SES Women
The purpose of this study is to investigate the feasibility of a mobile-phone based contingency management (CM) intervention for smoking in low-SES women.
- Trial name
- ProjectMIST (NCT03173274)
- Testing
- Brief Motivational Intervention, Contingency Management, Non-Contingent Reinforcement
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Brown University
Depression, Unipolar
Machine Learning to Predict Clinical Response to TMS
Major Depressive Disorder (MDD) is a common and debilitating illness. It affects a person's family and personal relationships, work, education, and life.
- Trial name
- LEARN (NCT03847688)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brown University
Substance Abuse
Contingency Management for Smoking in Substance Abusers
The aim of this study is to determine whether contingent reinforcement for smoking abstinence, compared to noncontingent reinforcement, increases the effectiveness of brief counseling and nicotine replacement on smoking…
- Trial name
- SCMSUD (NCT00807742)
- Testing
- Nicotine Replacement Treatment (NRT), Brief Advice, Contingency Management
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Brown University
Bipolar Disorder
Adjunctive Psychotherapy for Perinatal Bipolar Disorder
Bipolar disorder (BD) is a serious, disabling, and highly recurrent illness. The perinatal period dramatically increases risk for mood episodes in women with BD, but pregnancy complicates pharmacologic treatment decisions and…
- Trial name
- NCT02402738
- Testing
- Interpersonal and Social Rhythm Therapy, Enhanced Treatment as Usual
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Brown University
Mild-moderate Unipolar Depression; Persistent Negative Affect
Dismantling Mindfulness: Contributions of Attention vs. Acceptance
This study addresses NCCAM's request for research that investigates the neuropsychological mechanisms underlying mind-body therapies, and for precise criteria and better delineation of meditation practices.
- Trial name
- NCT01831362
- Testing
- Mindfulness-Based Cognitive Therapy, Focused Attention (FA), Open- Monitoring
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Brown University
Tobacco Use, Cigarette Smoking
Assessing Tobacco Product Choice When the Cost of Menthol Cigarettes Increases
In this study, participants will complete a behavioral economics laboratory task and validation field assessments to understand how menthol cigarette policy restrictions may affect tobacco product purchasing and use.
- Trial name
- NCT03612349
- Testing
- Experimental Tobacco Marketplace Task
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Obesity, Physical Activity
Small Monetary Incentives to Promote Exercise (Exercise4Good; EX4G)
This study is for physically inactive adults with an active membership at a Greater Providence Young Men's Christian Association (YMCA).
- Trial name
- NCT03134040
- Testing
- Incentives (Rebate), Incentives (Donation), Feedback
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brown University
Smoking Cessation, Nicotine Dependence
Varenicline and Motivational Advice for Smokers With Substance Use Disorders
The purpose of this study is to evaluate the effects of 12 weeks of varenicline as compared to nicotine replacement therapy for smoking cessation among outpatients in treatment for substance use disorders.
- Trial name
- VARSUD (NCT00756275)
- Testing
- Nicotine Replacement Treatment (NRT), varenicline, Behavioral counseling for smoking cessation
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Brown University
PrEP Uptake, Stimulant Abuse
Pepped on Pre-exposure Prophylaxis (PrEP): A Counseling and Problem-Solving PrEP Adherence Intervention for Stimulant Using Men Who Have Sex With Men (MSM).
Pepped on PrEP is an innovative pilot RCT designed by an interdisciplinary team to develop a counseling and problem-solving PrEP adherence intervention with a Behavioral Activation (BA) approach that aims to re-engage…
- Conditions
- PrEP Uptake, Stimulant Abuse, Adherence, Medication
- Trial name
- NCT03137342
- Testing
- Pepped on PrEP Package
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brown University