Clinical trials: sponsored by CHU de Reims
Type 1 Diabetes
Continuous Glucose Monitoring and Hypoglycemia Unawareness in Type 1 Diabetes
Looking for strict normoglycemia in type 1 diabetes increases the risk of hypoglycemia, exposing to hypoglycemia unawareness. It has been shown that the early correction of hypoglycemia can help recovering the perception of…
- Trial name
- NCT03605979
- Where
- France
- Volunteers
- 11 people
- Sponsor
- CHU de Reims
Anxiety, Premedication
Preoperative Anxiety Level, Premedications and General Anaesthetic Proceedings
Although it seems obvious that the high level of preoperative anxiety may affect intraoperative anaesthetic requirements and recovery adversely, there are several contradictory studies about this subject.
- Conditions
- Anxiety, Premedication, General Anaesthetic
- Trial name
- NCT03603873
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- CHU de Reims
Hidradenitis Suppurativa, Periodontal Diseases
Hidradenitis Suppurativa and Periodontal Diseases
Hidradenitis suppurativa or Verneuil's disease (HS) is a neglected and often overlooked chronic inflammatory skin disease. Nevertheless, it is frequent (1% of the general population) and deeply affects quality of life in patients…
- Trial name
- HSPDA (NCT03553888)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Small Intestinal Neuroendocrine Tumor
Resection of the Primary Tumor vs no Resection in Asymptomatic Patients With Unresectable Synchronous Liver Metastases From siNEN
Small Intestinal neuroendocrine Tumors (SiNETs) incidence is rising. Most of siNETs primaries are localized in jejunum/ileum. At the diagnosis, 50-70% of them present either lymph node (LN) and/or liver metastases (LM).
- Trial name
- SI-NET (NCT03442959)
- Testing
- Data record
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Osteoporosis
Osteoporosis Awareness Survey of Women in Champagne Ardenne
Osteoporosis is characterized by low bone mineral density and alterations in bone microarchitecture, leading to bone fragility and high risk of fractures.
- Trial name
- MPCosteoporose (NCT03537846)
- Where
- France
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Pregnancy
Assessment of Women's Insight and Understanding of Down's Syndrome Screening by Non-invasive Prenatal Testing (NIPT) During Their First Ultrasound
Down's syndrome is the leading cause for mental retardation in France. Screening for this chromosomal abnormality is systematically proposed during pregnancy.
- Trial name
- DEPIST21 (NCT03549286)
- Testing
- Questionnaire passation
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Patients With Heart Disease
Study of Sexual Dysfunction in Patients Included in a Cardiac Rehabilitation Program in Champagne-Ardenne
Sexual health is an important marker of individual quality of life and well-being of patients. Sexual dysfunction (SD) is common in patients with heart disease. Screening and management are recommended.
- Trial name
- SexualDysf (NCT03352817)
- Testing
- Cardiac rehabilitation
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
Intraabdominal Hypertension, Kidney Transplantation
Intraabdominal Hypertension After Kidney Transplantation
Intraabdominal hypertension (IAH) is a frequent and severe condition affecting intensive care patients. Gold standard for estimation of intraabdominal pressure is intravesical pressure (IVP) measurement.
- Trial name
- KITIV (NCT03478176)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Chronic Kidney Disease
Platelet Function in Hemodialysis Patient
The objective is to evaluate the function of the platelet in patients undergoing hemodialysis. The investigators will use the assay called PFA-100, an in vitro whole blood assay with three pathways of platelet activation to…
- Trial name
- NCT02792283
- Testing
- whole blood collection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Healthy Infants
Age-dependency of Thrombin Generation Using a New Standardized Assay
The aim of this study is to establish normal values of thrombin generation assay parameters in pediatrics, according to different age groups. The standardized thrombin generation assay "Genesia™" will be used.
- Trial name
- TGT (NCT03007108)
- Testing
- blood withdrawal
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Tracheal Intubation
Curarisation and Intubation Conditions During Videolaryngoscopy With Glidescope Titanium
In this prospective, randomized study, the investigators assess the intubation conditions during videolaryngoscopy with Glidescope Titanium whether patients receive (curare (Atracurium) group) or no (control group) within…
- Trial name
- GICAC (NCT02404142)
- Testing
- Curare (Atracurium), saline isotonic solution
- Where
- France
- Volunteers
- 64 people
- Sponsor
- CHU de Reims
Pregnant Women
Interest of the Injection of Morphine, in Addition to a Local Anesthetic When Performing a Combined Spinal-epidural for Labor Analgesia
The addition of morphine to a local anesthetic when performing an epidural analgesia during labor analgesia has improved the efficiency and the action duration of analgesia.
- Trial name
- MASEA (NCT02868944)
- Testing
- experimental group : sequential combined spinal epidural with local anesthetic injection (chirocaine) associated with morphine (sufentanil)., control group : sequential combined spinal epidural with local anesthetic injection (chirocaine) alone.
- Where
- France
- Volunteers
- 144 people
- Sponsor
- CHU de Reims
Handgrip Strength Test, Sarcopenia
Feasibility of Systematic Handgrip Strength (HGS) Testing and Short-term Changes in Muscle Strength in Digestive Cancer Patients Treated by Chemotherapy
Sarcopenia is defined as a loss in skeletal muscle mass and function (strength and/or performance). There is a high prevalence in elderly and in patients with cancer.
- Conditions
- Handgrip Strength Test, Sarcopenia, Digestive Cancer, Muscle Strength
- Trial name
- FIGHTDIGO (NCT02797197)
- Testing
- handgrip strength test, chemotherapy
- Volunteers
- 201 people
- Sponsor
- CHU de Reims
Severe Alcoholic Hepatitis
Assessment of the Predictive Value of Fecal Calprotectin for the Outcome of Severe Alcoholic Hepatitis
Severe alcoholic hepatitis, defined by a "Maddrey discriminant function" above 32, is associated with significant short-term mortality.
- Trial name
- CALPRO-HAA (NCT02808663)
- Testing
- fecal calprotectin concentration, blood collection
- Where
- France
- Volunteers
- 6 people
- Sponsor
- CHU de Reims
Endometrial Hyperplasia and Endometrial Cancers
Role of Senescence in the Development of Endometrial Cancer
Several molecular studies showed chromosomal alterations in patients with endometrial cancer, with gains in 1q, 19p, 19q, 8q, 10q and 10p and loss of 4q, 16q and 18q.
- Trial name
- NCT03338985
- Testing
- Genetic analysis
- Where
- France
- Volunteers
- 140 people
- Sponsor
- CHU de Reims
Autoimmune Bullous Dermatoses
Register of Autoimmune Bullous Dermatoses
Autoimmune bullous dermatoses are a group of diseases with chronic course. They are provoked by the production of autoantibodies against the dermal-epidermal junction or against the inter-keratinocyte junctions, resulting in the…
- Trial name
- REGIBUL (NCT02899923)
- Testing
- Data collection
- Where
- France
- Volunteers
- 750 people
- Sponsor
- CHU de Reims
Shoulder Pain
Transcultural Validation of the Oxford Shoulder Score for the French-speaking Population
Degenerative lesions of the shoulder occur very frequently and their incidence increases with age. The Constant-Murley score is currently considered the gold standard in Europe to assess the shoulder and is widely used by the…
- Trial name
- French-OSS (NCT03320356)
- Testing
- the French version of the Oxford Shoulder Score
- Volunteers
- 144 people
- Sponsor
- CHU de Reims
Premature Birth, Mother's Post-traumatic Reaction
Emotional Reactions of Mothers Facing Premature Births
Our intervention in the maternity and neonatal wards helped our sensibility to the immediate parental reaction to the premature birth.
- Conditions
- Premature Birth, Mother's Post-traumatic Reaction, Mother-infant Interactions
- Trial name
- mother's traum (NCT03345641)
- Testing
- describe precocious maternal impressions when confronting the premature birth of her infant
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Vitrectomy, Macular Thinning
The Role of Intravitreal Glucose in Macular Thinning Following Surgery for Retinal Detachment or Epimacular Membrane
Comparison between intravitreous glucose rate and macular thinning measured by Ocular Coherence Tomography (OCT) at 3 months post vitrectomy for retinal detachment or epimacular membrane.
- Trial name
- GLU-MAC (NCT02210481)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- CHU de Reims
Travel Medicine
French Travelers' Knowledge of Risk of Acquiring ESBL-PE
Since it is not routine practice in France to raise public awareness about the risk of acquiring multidrug resistant Enterobacteriaceae (MRE) during international travel, the investigators aimed to determine, among French…
- Trial name
- MDR bacteria (NCT03339947)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 191 people
- Sponsor
- CHU de Reims