Clinical trials: sponsored by CHU de Reims
Fluid Overload, Peritoneal Hyperpermeability
Hydratation Status at Initiation of Peritoneal Dialysis: Study of the Role of Peritoneal Permeability
Bioimpedance is recently known to be a reliable, reproducible and validated technic allowing determination of hydratation status in patients with chronic kidney disease treated with peritoneal dialysis (PD).
- Conditions
- Fluid Overload, Peritoneal Hyperpermeability, Peritoneal Dialysis, Chronic Kidney Disease
- Trial name
- NCT03322410
- Testing
- modified Peritoneal Equilibration test
- Where
- France
- Volunteers
- 40 people
- Sponsor
- CHU de Reims
Bullous Pemphigoid
Impact of Neurological Diseases on the Prognosis of Bullous Pemphigoid: A Retrospective Study of 178 Patients
Bullous pemphigoid affects mainly elderly patients. It is often associated with neurologic disorders, which represent a major risk factor of the disease
- Trial name
- NCT03320798
- Testing
- Data record
- Where
- France
- Volunteers
- 178 people
- Sponsor
- CHU de Reims
Celiac Disease
Interpretation of Serological Tests in the Diagnosis of Celiac Disease: Anti-deamidated Gliadin Peptide Antibodies Revisited
Celiac disease is an autoimmune disorder characterized by a chronic inflammation of the small bowel mucosa, triggered by the ingestion of gluten-containing grains.
- Trial name
- DGP-CeliacDis (NCT03320811)
- Testing
- Data record
- Where
- France
- Volunteers
- 2,026 people
- Sponsor
- CHU de Reims
Child With Adverse Drug Reactions
Adverse Drug Reactions in Pediatrics: Experience of a Regional Pharmacovigilance Center
Aim. - To describe the adverse drug reactions (ADR) and the drugs involved in pediatrics. Methods. - An observational study on all ADR notifications recorded in the French pharmaco-vigilance database by the Regional…
- Trial name
- Pediatry ADR (NCT03316014)
- Testing
- Adverse drug reaction
- Volunteers
- 632 people
- Sponsor
- CHU de Reims
Mesenteric Panniculitis
Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis
Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical.
- Trial name
- MP - Cancer (NCT03316001)
- Testing
- Review of multidetector row computed tomography scans
- Volunteers
- 288 people
- Sponsor
- CHU de Reims
Healthy Volunteers
Screening for Frailty at Home
"Many tools to evaluate frailty have been developed. However, at the time our study was designed, none of these instruments had been validated in terms of psychometric properties.
- Trial name
- SEGAm (NCT02852200)
- Testing
- SEGAm
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Hip Osteoarthritis
Efficacy of Viscosupplementation Associated With Intra-articular Corticosteroid Injection Versus Intra-articular Injection of Corticosteroids Alone in Osteoarthritis of Hip
The current management of osteoarthritis is based on non-pharmacological and pharmacological means which include intra-articular injections.
- Trial name
- VISCOSUPP-HIP (NCT02862639)
- Testing
- Experimental group, control group
- Where
- France
- Volunteers
- 43 people
- Sponsor
- CHU de Reims
Colon Cancer
LRP1 Methylation and Colon Cancer
Colorectal cancer (CRC) is a major public health problem in France and worldwide. CRC is the third most common cancer in incidence and mortality in France.
- Trial name
- NCT02786602
- Testing
- pyrosequencing
- Volunteers
- 345 people
- Sponsor
- CHU de Reims
Adapted Physical Activity and Cancer
Adapted Physical Activity in a Chemotherapy Ambulatory Care Unit: Feasibility and Impact on Fatigue, Anxiety and Depression in Cancer Patients
Physical activity has demonstrated efficacy in cancer prevention and improves quality of life and outcome in cancer survivors. Patients undergoing chemotherapy, especially those with advanced disease, may have symptoms leading to…
- Trial name
- UMACHAPA (NCT03049436)
- Testing
- Program of adapted physical activity
- Where
- France
- Volunteers
- 250 people
- Sponsor
- CHU de Reims
Alzheimer's Disease (AD) and Related Disorders
Non-pharmacological Care of Alzheimer's Disease: Benefice of Musical Interventions
Cares of Alzheimer's disease (AD) and related disorders are presenting a real public health challenge. Because of the limited effectiveness of pharmacological treatments, there is a growing interest in care approach based on…
- Trial name
- MusicAlzheimer (NCT02833870)
- Testing
- Musical intervention, Non-musical (cooking) intervention, Control with no intervention
- Where
- France
- Volunteers
- 150 people
- Sponsor
- CHU de Reims
Cholangiocarcinoma, Cancer of the Head of the Pancreas
Pancreatico-biliary Tumor Mutation Profiling in Bile Samples
The differential diagnosis between benign and malignant bile duct strictures is a difficult and demanding task for clinicians. Clinical, biochemical, and radiological characteristics of malignant biliary strictures are…
- Trial name
- ONCOBIL (NCT02893085)
- Testing
- bile sample analysis, biochemical markers, VEGF and MMPs, in bile samples
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Bullous Pemphigoid
Genetic Susceptibility and Influence of the Microbiomae in Bullous Pemphigoid
Autoimmune bullous dermatoses include pemphigus, bullous pemphigoid, pemphigoid gestationis, linear IgA dermatosis, mucous membrane pemphigoid, lichen planus pemphigoid, anti-p200 pemphigoid, epidermolysis bullosa acquisita and…
- Trial name
- MICROPB (NCT02874079)
- Testing
- Blood sample and cotton skin swabs
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Dementia
Evaluation of the Quality of Life in the Elderly With Dementia : Validation of a Specific Instrument
With nearly one million cases of dementia in France in 2010, Alzheimer's disease (AD) and related syndromes are a major public health issue.
- Trial name
- NCT02814773
- Testing
- questionnaires
- Where
- France
- Volunteers
- 310 people
- Sponsor
- CHU de Reims
Quality of Life, Muscular Dystrophies
Quality of Life in Neuromuscular Disease
A Quality work was conducted to enable the future construction of a Quality of Life Questionnaire Related to Health (HRQoL) in patients with slowly progressive neuromuscular disease (NMD) as myopathies and muscular dystrophies.
- Trial name
- QoLNMD (NCT02895763)
- Testing
- Form administrations
- Where
- France
- Volunteers
- 159 people
- Sponsor
- CHU de Reims
Lupus Erythematosus
Study of the Role of Soluble Forms of RAGE (sRAGE/esRAGE) as Diagnostic and Prognostic Biomarkers of Systemic Lupus Erythematosus.
Systemic Lupus Erythematosus (SLE) is the most common systemic autoimmune disease. The clinical manifestations are severe and affect multiple target organs such as the kidney, central nervous system, skin, heart and joints.
- Trial name
- R-PA14098 (NCT02891213)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- CHU de Reims
Abdominal Aortic Aneurysm
Measurement of Maximum Diameter of Native Abdominal Aortic Aneurysm by Angio-CT
Screening for an abdominal aortic aneurysm, monitoring its growth and evaluation of its risk of rupture are based on the measure of its maximum diameter.
- Trial name
- AAA-angioCT (NCT02875444)
- Testing
- Angio-CT
- Where
- France
- Volunteers
- 46 people
- Sponsor
- CHU de Reims
Indolent Cutaneous B Cell Lymphomas
Multiple Fields Radiotherapy Versus Intravenous Rituximab in the Treatment of Indolent Cutaneous Lymphomas B-cell With Multiple or Recurrent Lesions
Cutaneous lymphomas are the most frequent extranodal lymphomas after digestive lymphomas. A quarter are B-cell lymphomas. 80% of cutaneous B cell lymphomas are indolent cutaneous B cell lymphomas.
- Trial name
- RADIO-LYMPH (NCT02867553)
- Testing
- rituximab, Multi-fields radiotherapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- CHU de Reims
Adverse Drug Reaction
Serious Adverse Drug Reaction and Their Preventability
Introduction: Elderly aged over 65 years accounted for around 17.5% of the French general population. Adverse drug reactions (ADR) are common in this population. In elderly subject, prevalence of ADRs ranged from 4.3% to 63.0%.
- Trial name
- SADR (NCT02888834)
- Testing
- Adverse drug reaction
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Schizophrenia, Chronic Psychiatric Disorder
Mental Healthcare in Older Adults With Schizophrenia
As in the general population, there is a gradual and steady increase in life expectancy of patients with schizophrenia. But this increase is at a smaller scale, with a rate of premature death that is still 2 to 3 times higher…
- Trial name
- CSA (NCT02884739)
- Testing
- Data collection
- Where
- France
- Volunteers
- 685 people
- Sponsor
- CHU de Reims
Hairy-cell Leukemia
Rituximab in Hairy Cell Leukemia: a Multicenter Retrospective Study
Hairy-cell leukemia is a rare and indolent lymphoid disorder, representing 2% of all cases of lymphoid leukemias. Treatment of hairy-cell leukemia relies mainly on the purine analogs, cladribine and pentostatin, which have shown…
- Trial name
- RITUX-LEUKEMIA (NCT02883946)
- Testing
- Data collection
- Where
- France
- Volunteers
- 41 people
- Sponsor
- CHU de Reims