Clinical trials: sponsored by CHU de Reims
Systemic Sclerosis, Other Connective Tissue Disease
Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis
Systemic SClerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to vasculopathy and/or fibrosis.
- Conditions
- Systemic Sclerosis, Other Connective Tissue Disease, Systemic Lupus Erythematosus, Dermatomyositis
- Trial name
- NETOSE (NCT06462768)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Caregiver Feeling
Feeling of Caregivers After a Palliative Management of Extreme Premature Babies in Delivery Room.
Introduction : The birth of a child is usually a happy event that caregivers working in delivery rooms share with families. Unfortunately, newborns sometimes need palliative care as soon as birth occurs.
- Trial name
- NCT06458114
- Testing
- Assessment of caregiver feeling
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Systemic Lupus Erythematosus, Systemic Sclerosis
Neutrophil Extracellular Traps in Systemic Sclerosis
Systemic sclerosis (SSC) is a systemic disease characterized by limited or diffuse cutaneous sclerosis, microangiopathy, overproduction of autoantibodies and variable organ damage due to vasculopathy and/or fibrosis.
- Trial name
- NET-SSC (NCT03374618)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Pituitary Surgery
Copeptin in the Diagnosis of Post-operative Insipidus Diabetes After Pituitary Surgery
Endoscopic trans-sphenoidal pituitary endoscopic surgery is one of the main axes of management of tumours of the sellar region. Central diabetes insipidus is a frequent complication of endoscopic trans-sphenoidal pituitary…
- Trial name
- Copeptin-surg (NCT04326569)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 57 people
- Sponsor
- CHU de Reims
Type1diabetes
Advanced Glycation Products and Vascular Complications in Type 1 Diabetes
DIABAGE (Diabetes Advanced Glycation End products) study was conducted between 2015 and 2017. It included 196 type 1 diabetic patients with more than 10 years of diabetes.
- Trial name
- DIABAGE (NCT06458088)
- Where
- France
- Volunteers
- 196 people
- Sponsor
- CHU de Reims
Infection With Coronavirus SARS-CoV2
Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation
Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular…
- Trial name
- CAPACoV19 (NCT04356378)
- Testing
- Data record
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
Thromboembolic Event
Elaboration of a Prioritization Score for Pharmaceutical Interviews in Patients Treated With Oral Anticoagulants
Oral anticoagulants have a prominent place in the strategy of prevention and treatment of thromboembolic diseases, especially in patients with atrial fibrillation.
- Trial name
- NCT06100380
- Testing
- Survey
- Where
- France
- Volunteers
- 197 people
- Sponsor
- CHU de Reims
Rheumatoid Arthritis
Evaluation of a New Screening Method for Sarcopenia in Rheumatoid Arthritis
Evaluation of a new screening method for sarcopenia in rheumatoid arthritis
- Trial name
- SARCO-RA (NCT04933097)
- Testing
- Microfet2®
- Where
- France
- Volunteers
- 164 people
- Sponsor
- CHU de Reims
Total Hip Replacement Surgery
Analgesia in Total Hip Arthroplasty by Quadratus Lumborum Block
Patients are painful after total hip arthroplasty. These patients have significant co-morbidities. Analgesics cause significant side effects in this population.
- Trial name
- ATHAQLuB (NCT03666260)
- Testing
- Quadratus Lumborum Block, femoral block
- Where
- France
- Volunteers
- 179 people
- Sponsor
- CHU de Reims
Dental Care for Institutionalized Elderly Persons
Evaluation of the Agreement Between a Consultation With a Nurse Acquiring Three-dimensional Intraoral Images Made With a 3D Intraoral Camera and the Standard Consultation With a Dental Surgeon, in Institutionalized Elderly Subjects
The primary objective of this study will be to assess the agreement between a dental consultation with a nurse acquiring intraoral images, using a 3D intraoral camera, and a standard consultation with a dental surgeon, in…
- Trial name
- GEROdonto3D (NCT06387992)
- Testing
- Three-dimensional dental acquisition
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Subjects Aged 75 Years or More Living at Home
Impact of a Telephone Coaching Program on Evolution of Autonomy in Subjects Aged 75 Years or More Living at Home
Since the last few decades, developed societies have been evolving towards a global aging of their populations. This evolution has been accompanied by the problematic of the dependence of aging populations.
- Trial name
- Frailcoach (NCT04237077)
- Testing
- telephone coaching program, no telephone coaching program
- Where
- France
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Peritoneal Carcinomatosis
Preoperative Inflammatory Markers Predict Postoperative Complications After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Colorectal Carcinomatosis
A retrospective study of a single-center prospective database of patients who underwent curative CRS-HIPEC for peritoneal carcinomatosis (PC) of colo-rectal cancer (CRC), between September 2012 and July 2023 at Reims…
- Trial name
- NCT06318793
- Where
- France
- Volunteers
- 166 people
- Sponsor
- CHU de Reims
Adolescent Idiopathic Scoliosis
Effect of a Brace on the Adolescent Idiopathic Scoliosis Breathing
This study intends to investigate the effect of bracing on respiratory function in the treatment of adolescent idiopathic scoliosis (AIS).
- Trial name
- CTM biomec (NCT05749562)
- Testing
- Cheneau-Toulouse-Munster brace
- Where
- France
- Volunteers
- 12 people
- Sponsor
- CHU de Reims
Out of Hospital Cardiac Arrest Without ST-segment Elevation
Performance of Coronary CT Angiography to Rule Out Coronary Artery Disease After Out-of-hospital Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) has multiple etiologies. In the absence of ST-elevation myocardial infarction, percutaneous coronary intervention (PCI) is delayed.
- Trial name
- PERFECCT (NCT05961488)
- Testing
- Coronary Calcium Score and Coronary CT angiogram
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
Bullous Pemphigoid
Observational Study Assessing Outcomes, Treatment Patterns and Related Costs in Patients in Bullous Pemphigoid
The study is an observational, multi-center, prospective, non-interventional and open-label data collection study assessing outcomes, treatment patterns, adverse events and costs in patients diagnosed with bullous pemphigoid.
- Trial name
- EDP-PB (NCT02837965)
- Testing
- treatment with topical superpotent corticosteroid therapy, treatment with systemic therapy (methotrexate), treatment systemic therapy (prednisone)
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
Xerostomia
Validation of the French Version of the Xerostomia Inventory
The main objective of this study is to achieve cross-cultural and psychometric validation of the Xerostomia Inventory initially developed in English language into French Language.
- Trial name
- XIvf (NCT03009786)
- Testing
- Measurement of salivary flow
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Pancreatic Adenocarcinoma
Reorganization of the Healthcare System During COVID-19 Pandemic: Impact on Management of Patients With Exocrine Pancreatic Cancer
Pancreatic adenocarcinoma will be the 2nd cause of death by cancer in Europe in 2030. Pancreatic adenocarcinoma has poor prognosis with an all-stages combined 5-year survival rate below 8%.
- Trial name
- CAPANCOVID-19 (NCT04406571)
- Testing
- Data record
- Where
- France
- Volunteers
- 700 people
- Sponsor
- CHU de Reims
Asthma
Patient Education in Pregnant Women With Asthma
Pregnancy may impact treatment adherence in women with asthma. This is a major risk factor for asthma exacerbation, which may have an important impact for both women and the babies.
- Trial name
- TAPAGE (NCT05459012)
- Testing
- follow-up
- Where
- France
- Volunteers
- 5 people
- Sponsor
- CHU de Reims
Cystic Fibrosis, Periodontitis
Cystic Fibrosis and Periodontal Diseases
The number of CF adults is increasing year after year (61.7% in 2021) confirming that patients are living longer. These data do not leave aside the desire to see CF patients "age well" considering of all the comorbidities linked…
- Conditions
- Cystic Fibrosis, Periodontitis, Gingivitis
- Trial name
- MucoParo (NCT06133335)
- Testing
- Periodontal examination
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Pancreatic Ductal Adenocarcinoma (PDAC)
RPSA as a Potential Prognostic Biomarker of Pancreatic Cancer
PDAC (Pancreatic ductal adenocarcinoma) represents 90% of pancreatic tumors. The prognosis of PDAC remains poor at this time. Its management is based on surgery for early stages, associated with neoadjuvant and adjuvant…
- Trial name
- PaCaBioMarkeR (NCT04575363)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 90 people
- Sponsor
- CHU de Reims