Clinical trials: sponsored by CHU de Reims
Bullous Pemphigoid
Efficacy and Safety of Ustekinumab in Bullous Pemphigoid
Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease and typically affects the elderly. Clinically, BP is an intensely pruritic erythematous eruption with widespread blister formation.
- Trial name
- PB-USTE (NCT04117932)
- Testing
- Ustekinumab
- Where
- France
- Volunteers
- 18 people
- Sponsor
- CHU de Reims
Anorexia Nervosa
Efficiency of Virtual Reality Exposure Therapy in the Management of Body Dysmorphic Disorders in Female Adolescents With Anorexia Nervosa
Anorexia nervosa is defined in DSM V as a quantitative and qualitative dietary restriction resulting in significant weight loss, intense fear of weight gain, altered weight and body shape perception (body dysmorphic disorder) and…
- Trial name
- ANO-TERV (NCT04107870)
- Testing
- Virtual Reality Exposure Therapy sessions, Psychomotor therapy sessions
- Where
- France
- Volunteers
- 40 people
- Sponsor
- CHU de Reims
Shoulder Dislocation
Virtual Reality Hypnosis Versus Inhaled Nitrous Oxide in Anterior Shoulder Dislocation Reduction: an Open Multicenter Randomized Controlled Trial
Anterior shoulder dislocation (ASD) is a common situation in the emergency department (ED). Quick reductions lead to reduced mid and long term complications. No technique is superior to one another.
- Trial name
- NCT05388942
- Testing
- Virtual reality hypnosis, Nitrous oxide
- Where
- France
- Volunteers
- 126 people
- Sponsor
- CHU de Reims
Premature Birth
Prematurity and Parental Involvement in Child Development Care
The aims of the study is to evaluate the association between presence and parental participation in perinatal care and psychic development of the child at 24 months
- Trial name
- parentpart (NCT03950193)
- Testing
- Questionnaires to evaluate psychic development of the child
- Where
- France
- Volunteers
- 1 people
- Sponsor
- CHU de Reims
Peritoneal Carcinomatosis
A Nomogram to Predict Major Postoperative Complications After Cytoreductive Surgery and HIPEC Based on Pre and Peroperative Criteria: Which Patient Require Intensive Monitoring?
In this study, the investigators tend to highlight pre and peroperative factors that predict major postoperative complication after a surgery for resection of peritoneal carcinomatosis.
- Trial name
- NCT05547568
- Testing
- Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy
- Where
- France
- Volunteers
- 219 people
- Sponsor
- CHU de Reims
Colorectal Cancer
Identification of New Diagnostic Protein Markers for Colorectal Cancer
The search for biochemical markers in patient's blood for non-invasive colorectal cancer diagnostic has not yielded satisfactory results to date.
- Trial name
- EXOSCOL01 (NCT04394572)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CHU de Reims
Domestic Violence
The Reporting of Domestic Violence by Patients in the Emergency Department of the Reims University Hospital Center
Domestic violence is defined as violence carried out by one of the partners in a relationship of domination. This can be verbal, psychological, physical or sexual.
- Trial name
- NCT05543395
- Testing
- Domestic Violence Questionnaire
- Where
- France
- Volunteers
- 47 people
- Sponsor
- CHU de Reims
Kidney Transplant Infection
Study of Pulmonary Infections (Pneumonia) in Kidney Transplant Recipients Admitted to Hospital
The investigators aimed to identify prognosis factors associated with in-hospital complications and assess the epidemiology, management, and outcomes of community-acquired pneumonia in a kidney transplant recipients' cohort.
- Trial name
- NCT05142748
- Where
- France
- Volunteers
- 132 people
- Sponsor
- CHU de Reims
Coronavirus Infections
CoViD-19 Patient in Reims University Hospital in March to April 2020
Medical context: Follow-up of a retrospective cohort of 499 cases of CoViD-19, hospitalized at the University Hospital of Reims during the health crisis, prospectively up to two years of follow-up.
- Trial name
- COVID-Reims (NCT04553575)
- Testing
- serology
- Where
- France
- Volunteers
- 127 people
- Sponsor
- CHU de Reims
Obesity, Binge-Eating Disorder
fMRI Study of Emotion Regulation in Patients Suffering From Obesity With or Without Binge Eating Disorder and Seeking Bariatric Surgery
Obesity is a major public health problem and Binge eating disorder (BED) is very frequently observed in patients considered for weight loss surgery and seems to influence their outcome critically.
- Trial name
- OBéMO (NCT05131256)
- Testing
- Neurofunctional characterization of emotional regulation (fMRI)
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Cancer
Oncology Care Pathway's Modifications Impact During COVID-19 Pandemic : the ONCOCARE-COV Study
In december 2019, SARS-CoV2 and its clinical manifestations, COVID-19, appeared in China and caused a pandemic. It led decision makers to prioritize emergency and intensive care dedicated to infection management.
- Trial name
- ONCOCARE-COV (NCT04445870)
- Testing
- data record
- Where
- France
- Volunteers
- 100 people
- Sponsor
- CHU de Reims
Diabetes Mellitus
Diabetes Mellitus and Pregnancy : Knowledge Assessment
Diabetes, a chronic and frequent disease, is a risk factor of pregnancy complications such as preeclampsia, congenital malformations and macrosomia.
- Trial name
- DMPKA (NCT04350879)
- Testing
- Data record
- Where
- France
- Volunteers
- 122 people
- Sponsor
- CHU de Reims
Amikacin Treatment
Prescription Strategies of Amikacin in Intensive Care Patients on Renal Replacement Therapy: an Observational Prospective Multicenter Study
Amikacin is the aminoglycoside of choice for treatment of severe infections in intensive care. An achievement of its objectives in pharmacokinetics and pharmacodynamics is difficult in intensive care patients because of…
- Trial name
- AMIDIAL-ICU (NCT04322019)
- Testing
- Data record
- Where
- France
- Volunteers
- 112 people
- Sponsor
- CHU de Reims
Myotonic Dystrophy Type 1 (DM1)
Breathlessness Assessment in Adult Patients With Myotonic Dystrophy Type 1
Myotonic dystrophy type 1 (DM1) is one of the most common neuromuscular diseases in adults. As respiratory dysfunction is the most common cause of death in patients with DM1, a respiratory disease progression must be monitored…
- Trial name
- NCT04835298
- Testing
- Dyspnea
- Where
- France
- Volunteers
- 34 people
- Sponsor
- CHU de Reims
Inflammatory Bowel Diseases, Periodontal Diseases
Prevalence of Periodontal Diseases in IBD
Periodontal diseases are highly prevalent inflammatory diseases. It is now well known that they are correlated with numerous systemic diseases as : diabetes, chronic obstructive pulmonary disease, metabolic syndrome or rheumatoid…
- Trial name
- MICIMaP (NCT04380922)
- Testing
- Periodontal screening
- Where
- France
- Volunteers
- 60 people
- Sponsor
- CHU de Reims
Cancer
The Use of Cannabidiol in Cancer Patients
Alternative and complementary medicines (MAC) are commonly used by cancer patients to help them to face with anticancer treatment, reduce oncology symptoms and/or anticancer treatment adverse effects, detoxifying the body.
- Trial name
- CANPADIOL (NCT05407298)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 350 people
- Sponsor
- CHU de Reims
Amoxicillin Crystalluria
Incidence, Risk Factors and Impact on Renal Function of the Appearance of Crystalluria Under High-dose Intravenous Amoxicillin
Intravenous high-dose amoxicillin is a frequently prescribed antibiotic in intensive care units and infectious disease departments, in such indications as meningitis, endocarditis, listeriosis, or documented susceptible…
- Trial name
- CRISTAMOX (NCT02853292)
- Testing
- urine collection
- Where
- France
- Volunteers
- 153 people
- Sponsor
- CHU de Reims
Covid19, Burnout, Professional
Burnout, Stress and Coping Strategies: Impact of the Covid-19 Epidemic
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus detected in Wuhan, China on December 2019. This virus is responsible for the infectious respiratory disease called Covid-19.
- Trial name
- Au20-15 (NCT04834882)
- Testing
- Data collection (
- Where
- France
- Volunteers
- 649 people
- Sponsor
- CHU de Reims
Chronic Obstructive Pulmonary Disease
Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem
Pseudomonas aeruginosa (PA ) is associated with chronic lung infections in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- MiPAD (NCT03008746)
- Testing
- water used for oral wash, sputum, oral wash
- Where
- France
- Volunteers
- 58 people
- Sponsor
- CHU de Reims
Diabetes Mellitus, Type 1
Interest of SmartGuard Technology (Predictive System for Stopping Insulin Before Hypoglycemia) in Children With Type 1 Diabetes Treated With Insulin Pump
Management of children and adolescents with type 1 diabetes is essentially insulin therapy using insulin pump, allowing the improvement of the glycemic balance.
- Trial name
- NCT03882463
- Testing
- Continuous glucose monitoring with the stop insulin pump function
- Where
- France
- Volunteers
- 34 people
- Sponsor
- CHU de Reims