Clinical trials: sponsored by CHU de Reims
Pregnancy
Relevance of Ultrasound Screening for Foetal Macrosomia
Management of fetal macrosomia is based on a suspicion of macrosomia (no certainty before birth). This management is an artificial induction of labour for an earlier delivery and therefore a lower fetal weight gain.
- Trial name
- USmacro (NCT04443205)
- Testing
- Data record
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- CHU de Reims
Abnormal Cytology
Oncogenous HPV DNA Integration (Intégration De l'ADN Des HPV Oncogènes)
High-risk human papillomavirus (HR-HPV) are involved in cervical cancer development. Integration of HR-HPV DNA in cellular genomes is considered as a major event in the cervical cancer development.
- Trial name
- IDAHO (NCT02864121)
- Testing
- all patients included in IDAHO study
- Where
- France
- Volunteers
- 407 people
- Sponsor
- CHU de Reims
Cochlear Implantation
Radiologic Criteria for Round Window Visibility Prediction in Cochlear Implantation
The aim of the study is to identify the scannographic criterion the most relevant to predict the round window visibility during cochlear implantation.
- Trial name
- R-PO18155 (NCT03950375)
- Where
- France
- Volunteers
- 23 people
- Sponsor
- CHU de Reims
Shock
Value of Cardiac Output Monitoring by Supra-sternal Doppler/Echocardiography in Intensive Care Unit
The aim of this study is to evaluate the concordance between the measurement of cardiac blood flow by non-invasive supra sternal ultrasound and the measurements performed by invasive monitoring in intensive care patients already…
- Trial name
- SSdopler (NCT03952871)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- CHU de Reims
Slow Language Impairment
Better Understanding Slow Language Impairment
This study was designed to examine the development of children aged 6 to 10 with slow language impairment (SLI). The aim was threefold: (1) to investigate language skills of children with SLI at different levels - formal…
- Trial name
- SLI:COGGEN (NCT03660995)
- Testing
- Evaluation of language skills and procedural learning of children with SLI and their controls. DNA sampling.
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Parotid Tumor
Intra-parotid Facial Nerve Tractography
The aim of the study is to evaluate concordance between the facial nerve's path in the parotid evaluated by radiologist in preoperatively and the facial nerve's path in the parotid evaluated by surgeon in peroperatively.
- Trial name
- R-PO19053 (NCT03950323)
- Testing
- MRI with Facial nerve tractography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- CHU de Reims
Brainstem Response
Use of BRASS in Sedated Critically-ill Patients as a Predictable Mortality Factor
Sedation is used for 30 to 70 % of all intensive care unit (ICU) patients. Deep sedation can be used for lot of disease like acute respiratory distress syndrome, septic shock.
- Trial name
- BRASS-ICU (NCT03835091)
- Testing
- BRASS score
- Where
- France
- Volunteers
- 110 people
- Sponsor
- CHU de Reims
Pancreatic Resection
Per-operative Exploration of the Peri-pancreatic Lymphatic Pathways During Pancreatic Surgical Resection
Short description of the protocol intended for the lay public. Include a brief statement of the study hypothesis (Limit : 5000 characters) Pancreatic cancer has a poor prognosis. Surgical resection is the only curative treatment.
- Trial name
- NCT03597230
- Testing
- Dye
- Where
- France
- Volunteers
- 20 people
- Sponsor
- CHU de Reims
Sudden Death in Children
Impact of Information Campaign's Alongside Maternity Staff About Bedding Infant
It is now well established that infants should be placed on the back only in a SleepSack without coverage or plush or pillow on a firm mattress in a bedroom.
- Trial name
- NCT03934242
- Testing
- Questionnaire on new born's bedding
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Critical Limb Ischemia
Cell Therapy in Critical Limb Ischemia
Study drug and dosage form : Umbilical cord-derived mesenchymal stem cells (HB-MSC1) Dose and route of administration : 60 × 106 cells or 120 x 106 cells to be injected as 30 individual intramuscular injections, once at V0 within…
- Trial name
- CLI (NCT03994666)
- Testing
- allogeneic umbilical cord-derived mesenchymal stem cells
- Where
- France
- Volunteers
- 30 people
- Sponsor
- CHU de Reims
Autosomal Dominant Polycystic Kidney Disease
ADPKD and Peritoneal Dialysis: How Anticipate Peritoneal Pressure?
Autosomal dominant polycystic kidney disease (ADPKD) is first genetic kidney disease and fourth etiology of end stage renal disease in the world. Peritoneal dialysis is underuse in this population.
- Trial name
- PDP-ADPKD (NCT03970018)
- Testing
- Intra-peritoneal pressure
- Where
- France
- Volunteers
- 210 people
- Sponsor
- CHU de Reims
Fetal Neuroprotection
Magnesium Sulfate (MgSO4) and Fetal Heart Rate (FHR) in Case of Prematurity
Type of study: prospective descriptive monocentric study Population: 2 groups: -Exposed group: pregnant patient between 24AW+0day and 32AW+0day receiving magnesium sulfate for fetal neuroprotection in the doubt of premature…
- Trial name
- NCT03956121
- Testing
- injection of magnesium sulfate
- Where
- France
- Volunteers
- 57 people
- Sponsor
- CHU de Reims
Cervical Radiculopathy, Cervical Spinal Fusion
FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC®
Cervical degenerative disease is an almost universal concomitant of human aging. Over half of the middle aged population has cervical spondylosis.
- Conditions
- Cervical Radiculopathy, Cervical Spinal Fusion, Cervical Myelopathy
- Trial name
- NCT03950349
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Prosthesis and Bone Infections, Cutibacterium Acnes
Cutibacterium Acnes in Bone and Joint Infections
Prosthetic Joint Infections (PJIs) are increasing with the use of orthopedic devices on an ageing population. Cutibacterium acnes is a commensal organism that plays an important role in the ecosystem healthy human skin, yet this…
- Trial name
- CaBJI (NCT03950063)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Gonarthrosis
Clinical and Radiological Impact of Tibial Cutting Int Total Knee Arthroplasty, Accelerated Navigation Versus Extramedullary Targeting
Type of study : Superiority study, comparative, randomized, double-blind (patient and evaluator will be blind from the randomization group), multicenter, prospective inclusion.
- Trial name
- NCT03951545
- Testing
- First line total knee replacement for gonarthrosis .
- Where
- France
- Volunteers
- 382 people
- Sponsor
- CHU de Reims
Neuroendocrine Tumors
Measurement Variability of Liver Metastases From Neuroendocrine Tumors on Different Magnetic Resonance Imaging Sequences
The aim of our study is to assess variability of measurements of liver metastases from neuroendocrine tumors (NET) on different magnetic resonance imaging (MRI) sequences.
- Trial name
- NETMRI (NCT03948841)
- Testing
- magnetic resonance imaging
- Where
- France
- Volunteers
- 41 people
- Sponsor
- CHU de Reims
Obesity
Rapid Eating Is Linked to Emotional Eating in Obese Women Relieving From Bariatric Surgery
The aim of the study was to analyse eating rate in comparison to other aspects of eating habits in women suffering from severe/massive obesity.
- Trial name
- BS-Women (NCT03949595)
- Testing
- Data collection
- Where
- France
- Volunteers
- 116 people
- Sponsor
- CHU de Reims
Polycystic Kidney Diseases
Outcome of Autosomal Dominant Polycystic Kidney Disease Patients on Peritoneal Dialysis: a National Retrospective Study Based on Two French Registries (the French Language Peritoneal Dialysis Registry and the French Renal Epidemiology and Information Network).
Pathological features of Autosomal Dominant Polycystic Kidney disease (ADPKD) include enlarged kidney volume, a higher frequency of digestive diverticulitis and abdominal wall hernias.
- Trial name
- ADPKDPD (NCT03948113)
- Testing
- Dialysis
- Where
- France
- Volunteers
- 17,350 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Geophagia
Prevalence of Geophagy and Knowledge About Its Health Effects Among Native Sub-Saharan Africa, Caribbean and South America Healthy Adults Living in France
Since geophagy is widespread among women from Sub-Saharan Africa, South America and the Caribbean, we aimed to determine the frequency of geophagy and the level of knowledge about its health effects among healthy adults…
- Trial name
- Prevalgeophagy (NCT03948126)
- Testing
- Questionnaire about geophagia (knowledge about soil/clay consumption and knowledge of the health effects of geophagy)
- Where
- France
- Volunteers
- 101 people
- Sponsor
- CHU de Reims
Clinical Research Inclusion
Clinical Research and Data Collection During the Investigation: Influence of a Dedicated Staff
The aim of the study was to evaluate the interest of the recourse of a staff dedicated as CRA to data collection in clinical research
- Trial name
- CRA-MD (NCT03946501)
- Testing
- Data collection
- Where
- France
- Volunteers
- 400 people
- Sponsor
- CHU de Reims