Clinical trials: sponsored by Capital Medical University
Mild Cognitive Impairment
Effect of Vitamin D and Folic Acid on Mild Cognitive Impairment
The purpose of this study is to investigate the effects of Vitamin D3 combined with Folic Acid on mild cognitive impairment (MCI).
- Trial name
- NCT07486141
- Testing
- Vitamin D3 (800 IU/d) and Folic Acid(0.4mg/d), Vitamin D3 (1600 IU/d) and Folic Acid(0.4mg/d)
- Where
- China
- Volunteers
- 380 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Therapy -2
This study is a prospective, multicenter, open-label, randomized controlled clinical trial. The investigators will apply albumin to the reperfusion treatment of patients with acute ischemic stroke in the anterior circulation.
- Trial name
- ARISE-2 (NCT07263308)
- Testing
- Albumin, Endovascular treatment
- Where
- 61 sites in China
- Volunteers
- 1,192 people
- Sponsor
- Capital Medical University
Pregnancy, Dietary Inflammatory Index (DII)
Pregnancy Anti-inflammatory Diet Intervention Study
Dietary patterns may influence maternal inflammatory status and pregnancy outcomes. However, structured anti-inflammatory dietary interventions specifically designed for pregnant women remain limited.
- Trial name
- PAID2026 (NCT07890441)
- Testing
- Anti-inflammatory Dietary Intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Influenza, Human
Evaluation of the Efficacy and Safety of 102D-6 in the Treatment of Acute Uncomplicated Influenza
The goal of this Phase II/III study is to investigate the safty and efficacy of 102D-6 in adolescents and adults with influenza. The main aim to answer: 1.
- Trial name
- NCT07893847
- Testing
- 20 mg 102D-6 dry suspension, 40 mg 102D-6 dry suspension
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Capital Medical University
Respiratory Viral Infections, Influenza
Effect of MxA Guidance on Antiviral Treatment in Respiratory Viral Infections
The goal of this clinical trial is to evaluate the effects of myxovirus resistance protein A (MxA)-guided antiviral treatment on treatment duration and adverse outcomes in adults hospitalized with influenza or COVID-19, compared…
- Conditions
- Respiratory Viral Infections, Influenza, SARS CoV 2 Infection
- Trial name
- NCT07892872
- Testing
- Baseline MxA testing, Serial MxA testing, MxA result feedback and antiviral treatment recommendations
- Where
- China
- Volunteers
- 618 people
- Sponsor
- Capital Medical University
Mechanical Ventilation
Titration of PS Guided by FI : A Pilot Study
The goal of this single-center, pilot, randomized controlled trial is to evaluate the feasibility and preliminary efficacy of using the Flow Index (FI) to guide Pressure Support (PS) titration in adult patients receiving Pressure…
- Trial name
- NCT07769307
- Testing
- FI-guided ventilator support adjustment, Conventional PS titration
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Constipation
Oat Milk for Laxation
This study intends to recruit 90-100 constipated participants aged 25-50 years, including an equal number of males and females, from the faculty and logistics staff of Capital Medical University.
- Trial name
- NCT07302542
- Testing
- oat milk
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Meningioma, CDK4/6 Inhibitor
IN10018 in Combination With Dalpiciclib for Progressive Meningiomas
This open-label Phase Ib study will evaluate the safety, tolerability, and preliminary effectiveness of IN10018 in combination with dalpiciclib in adults with progressive meningiomas.
- Trial name
- NCT07652762
- Testing
- Ifebemtinib, Dalpiciclib
- Where
- 2 sites in China
- Volunteers
- 24 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy (PROTECT-2)
Ischemic post-conditioning is a neuroprotective strategy that has been proven to attenuate reperfusion injury in animal models of stroke.
- Trial name
- NCT05789823
- Testing
- Mechanical thrombectomy combined with ischemic post-conditioning, Mechanical thrombectomy alone
- Where
- 6 sites in China
- Volunteers
- 160 people
- Sponsor
- Capital Medical University
Sarcopenia, Breast Cancer
Exercise Intervention for Breast Cancer Patients With Sarcopenia
Sarcopenia is a common yet underrecognized complication in breast cancer survivors during rehabilitation, characterized by loss of muscle mass, reduced muscle strength, and impaired physical function, which adversely affects…
- Trial name
- EX-BCSarc (NCT07732101)
- Testing
- "Exercise for Muscle Health" Program
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL-2)
This phase 2, multicenter, randomized, double-blind, placebo-controlled trial will evaluate the efficacy and safety of anisodine hydrobromide in patients with acute ischemic stroke undergoing endovascular thrombectomy.
- Trial name
- NCT07800572
- Testing
- Anisodine Hydrobromide
- Where
- 13 sites in China
- Volunteers
- 204 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion Stroke
This is an investigator-initiated phase III clinical trial employing a randomized, double-blind, placebo-controlled design. The primary objective of this study is to investigate the efficacy and safety of an interleukin-6…
- Trial name
- IRIS-3 (NCT07509645)
- Testing
- Tocilizumab
- Where
- 30 sites in China
- Volunteers
- 348 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke, Cerebral Autoregulation
Ultra-early Identification of Futile Recanalization After Reperfusion Therapy in Acute Ischemic Stroke Based on Cerebral Autoregulation Monitoring
This multicenter, prospective, and interventional diagnostic accuracy study enrolls patients undergoing thrombectomy with intraoperative cerebral autoregulation monitoring and follows them up at predefined time points up to 90…
- Trial name
- FACTOR (NCT07747701)
- Testing
- NIRS-based cerebral oxygenation and blood pressure monitoring, Carotid compression test
- Where
- 4 sites in China
- Volunteers
- 227 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Acute Ischemic Stroke
Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2
This study is a randomized, double-blind, placebo-controlled clinical trial. Investigators aim to assess the efficacy and safety of interleukin-6 receptor inhibitor combined with endovascular treatment in patients with acute…
- Trial name
- IRIS-2 (NCT07263776)
- Testing
- Tocilizumab
- Where
- 54 sites in China
- Volunteers
- 692 people
- Sponsor
- Capital Medical University
Condition Category Concordance
3M-6D Educational Intervention to Improve LLM-Assisted Medical Consultation in Neurology Outpatients
This study will evaluate whether three-minute six-dimension education (3M-6D education) can improve the reliability of large language models (LLMs) as medical assistants in neurology outpatients.
- Trial name
- LAMP-2 (NCT07844044)
- Testing
- three minutes six dimensions education, ChatGPT
- Where
- 4 sites in China
- Volunteers
- 396 people
- Sponsor
- Capital Medical University
Major Depressive Disorder (MDD)
Personalized Accelerated iTBS Versus Sham for Major Depressive Disorder
This randomized, double-blind, sham-controlled, parallel-group clinical trial will evaluate the efficacy and safety of individualized functional connectivity-guided accelerated intermittent theta-burst stimulation (iTBS) in…
- Trial name
- iTBS-MDD (NCT07843875)
- Testing
- Personalized Functional-Connectivity-Targeted Accelerated iTBS
- Volunteers
- 90 people
- Sponsor
- Capital Medical University
Internal Carotid Artery Stenosis
Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis
This study aims to explore the efficacy of Intermittent Hypoxia Treatment (IHT) in preventing peri-operative embolism-related microinfarcts among patients with severe internal carotid artery stenosis (ICAS) undergoing carotid…
- Trial name
- NCT07837011
- Testing
- intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke, Cerebral Infarction
Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)
Stroke is the second leading cause of death worldwide, and ischemic stroke is the most frequent type. Intravenous thrombolysis with recombinant tissue plasminogen activator within 4.5 hours of symptom onset is the most effective…
- Trial name
- TREND-IVT (NCT06548971)
- Testing
- Aspirin, Best medical management
- Where
- 119 sites in China
- Volunteers
- 1,184 people
- Sponsor
- Capital Medical University
Chronic Kidney Disease, Osteoporosis
Clinical Study on a New Diagnostic Strategy for Osteoporosis and Sarcopenia in Chronic Kidney Disease Patients Based on MRI-FF
This is a single-center, observational cohort study aiming to validate the diagnostic value of MRI-FF in identifying osteoporosis and sarcopenia in patients with chronic kidney disease (CKD).
- Trial name
- NCT07645794
- Testing
- MRI-FF Scan
- Where
- China
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
Efficacy and Safety of Home-based Structured Physical Exercise in Patients With Acute Ischemic Stroke
This study is a randomized controlled, open-label, blinded endpoint trial. The investigators aim to assess the efficacy and safety of home-based structured physical exercise in participants with acute ischemic stroke.
- Trial name
- HOPE-STROKE 2 (NCT07271082)
- Testing
- Exercise intervention
- Where
- 6 sites in China
- Volunteers
- 208 people
- Sponsor
- Capital Medical University