Clinical trials: sponsored by Capital Medical University
Elderly Patients, Acute Ischemic Stroke
Protective Effects of RIC in Elderly With Acute Ischemic Stroke Complicating Acute Coronary Syndrome
Remote ischemic conditioning (RIC) is a noninvasive strategy in which one or more cycles of brief and transient limb ischemia confers protection against prolonged and severe ischemia in distant organs.This study aimed to…
- Conditions
- Elderly Patients, Acute Ischemic Stroke, Acute Coronary Syndrome
- Trial name
- RIC-ACS (NCT03868007)
- Testing
- RIC
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Sepsis, Viral Pneumonia
Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study
The goal of this observational study is to describe the immune signature of acute pulmonary infection.The main questions it aims to answer are: 1. Nasal mucosal immune response in patients with influenza infection 2.
- Conditions
- Sepsis, Viral Pneumonia, Influenza, Upper Respiratory Tract Infection
- Trial name
- DISPLAY (NCT05612893)
- Testing
- pathogen
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Hypertension,Essential, Prehypertension
The Antihypertensive Effect of Remote Ischemic Conditioning (RIC-HTN).
This study intends to further reveal the antihypertensive effect of LRIC and explore its potential mechanisms.
- Trial name
- NCT04915313
- Testing
- Remote ischemic conditioning (RIC)
- Where
- 3 sites in China
- Volunteers
- 95 people
- Sponsor
- Capital Medical University
Hemodialysis, Cerebral Blood Flow
Association Between Cerebral Blood Flow Change and Cognitive Function in Hemodialysis Patients
The prevalence of cognitive impairment in maintenance hemodialysis (MHD) patients is 3 to 5 times higher than that in ordinary people, so it is essential to find the associated risk factors in this population.
- Conditions
- Hemodialysis, Cerebral Blood Flow, Cognitive Function, Magnetic Resonance Imaging
- Trial name
- NCT05555836
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Stroke, Rehabilitation; Tobacco Use
Quantitative Prognostic Analysis of Upper Limb Motor Dysfunction After Stroke
30% - 66% of stroke survivors have upper limb dysfunction. Effective rehabilitation can improve the prognosis, but the rehabilitation resources are limited.
- Conditions
- Stroke, Rehabilitation; Tobacco Use, Upper Extremity Dysfunction, Prognosis
- Trial name
- NCT05410054
- Testing
- no intervention
- Volunteers
- 178 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Stroke, Upper Extremity Dysfunction
Dual Channel Rehabilitation Technology Promotes Rapid Recovery of Upper Limbs After Stroke
The injury and remodeling mechanism about upper extremity motor network after stroke is not clear. There are few studies on the motor network covering cortex, white matter and blood perfusion at the time.
- Conditions
- Stroke, Upper Extremity Dysfunction, Transcranial Direct Current Stimulation, Image, Body
- Trial name
- NCT04944680
- Testing
- Transcranial Direct Current Stimulation therapy, Motor imagery therapy, Transcranial Direct Current Stimulation and motor imagery therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Acute Ischemic Stroke
Hypothermia With Intrajugular Cooling in Acute Ischemic Stroke Thrombectomy
Hypothermia with intrajugular cooling is a neuroprotective strategy that has been proven to minimize brain damage and maximize functional preservation in animal models of stroke.
- Trial name
- PICNIC (NCT05488392)
- Testing
- Hypothermia with intrajugular cooling
- Volunteers
- 15 people
- Sponsor
- Capital Medical University
Acute Stroke
Tirofiban for the Prevention of Neurological Deterioration in Acute Ischemic Stroke
Currently, dual antiplatelet therapy with aspirin and clopidogrel (with loading doses) is widely used for patients with acute ischemic stroke.
- Trial name
- TREND (NCT04491695)
- Testing
- Tirofiban Hydrochloride, Oral antiplatelet
- Where
- 19 sites in China
- Volunteers
- 420 people
- Sponsor
- Capital Medical University
Intracerebral Hemorrhage, Acute Stroke
Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease. Currently, ICH has been a devastating type of stroke that lacking effective therapy.
- Trial name
- RICH-2 (NCT04657133)
- Testing
- Remote ischemic conditioning, Standard medication therapy
- Where
- 13 sites in China
- Volunteers
- 452 people
- Sponsor
- Capital Medical University
Cerebral Artery Occlusion
Remote Ischemic Conditioning for Chronic Cerebral Artery Occlusion
Chronic cerebral artery occlusion (CCAO), which is characterized by the pathophysiological change of long-term cerebral hemodynamic disorder, is one of the major risk factors affect the occurrence and recurrence of ischemic…
- Trial name
- NCT05342714
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
Acute Stroke, Ischemic Stroke, Acute
The Prehospital Administration of Normobaric Oxygen in Suspected Stroke
The primary purpose of this study is to explore the feasibility and safety of normobaric oxygen therapy (NBO) under pre-hospital condition in patients with suspected stroke.
- Trial name
- NO SUSPENSION (NCT05351073)
- Testing
- NBO
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Intracranial Stenosis
The Predictive Value of Retinal Vascular Signs for Intracranial Artery Stenosis (RVS-ICAS)
Intracranial artery stenosis (ICAS) is a leading cause of ischemic stroke worldwide, contributing to the global burden of stroke, particularly in the Asian population.
- Trial name
- RVS-ICAS (NCT05270746)
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Chronic Endometritis
RCT(Randomized Clinical Trial ) of Antibiotic Therapy in Chronic Endometritis
120 cases with a diagnosis of chronic endometritis, confirmed by the presence of plasma cells in endometrial biopsy sample identified by immunohistochemical staining using CD138 antibody, have been recruited.
- Trial name
- NCT02648698
- Testing
- Antibiotics
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Acute Ischemic Stroke
Acute Ischemic Stroke Registry for Endovascular Treatment
The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study.
- Trial name
- NCT05213754
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Cerebral Amyloid Angiopathy
Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA)
Cerebral amyloid angiopathy (CAA) is a common form of cerebral small vessel disease, characterized by symptomatic intracerebral hemorrhage and cognitive impairment.
- Trial name
- NCT05207475
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Mechanical Ventilation
Use of Pressure Muscle Index to Avoid Over-assistance During Pressure Support Ventilation
Pressure support ventilation (PSV) is the most commonly used mode in mechanical ventilated patients. Studies have shown that over-assistance was prevalent in patients undergoing PSV.
- Trial name
- NCT05026463
- Testing
- Inspiratory support level
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Tracheostomy Decannulation, Acquired Brain Injury
Comparison of the Decannulation Protocol With Suctioning and Capping in Severe Acquired Brain Injury Patients
Single-center randomized trail focused on tracheostomized patients with severe acquired brain injury , comparing two different decannulation protocols: 1.
- Trial name
- NCT04835272
- Testing
- the Decannulation Protocol With Suctioning
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Intrauterine Adhesion
Hysteroscopic "Hot Knife" and "Cold Knife" in the Treatment of the Intrauterine Adhesion
In this prospective, randomized controlled trial，the investigators wish to explore the difference of therapeutic effect and prognosis between "hot knife" and "cold knife" in the treatment of uterine adhesion under hysteroscopy.
- Trial name
- NCT04936347
- Testing
- cold knife, hot knife
- Where
- China
- Volunteers
- 802 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Asherman Syndrome
Estrogen in the Prevention of Adhesion Reformation
Asherman syndrome, which occurs after trauma to the basalis layer of the endometrium.It seems that the role of postoperative estrogen therapy in the prevention of recurrence of IU adhesions is still controversial.
- Trial name
- NCT03620929
- Testing
- Estradiol Valerate
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Fu Xing Hospital, Capital Medical University