Clinical trials: sponsored by Capital Medical University
Mechanical Ventilation
Compare the Effects of Remifentanil and Fentanyl on the Duration of Mechanical Ventilation of ICU Patients
To verify whether remifentanil is more beneficial to reduce the duration of mechanical ventilation, shorten the interval from SBT to extubation, reduce the incidence of adverse events, reduce the workload of nursing staff, reduce…
- Trial name
- NCT05014711
- Testing
- Remifentanil, Fentanyl
- Where
- China
- Volunteers
- 254 people
- Sponsor
- Capital Medical University
Gestational Diabetes Mellitus, Hypertensive Disorder of Pregnancy
Effects of Dietary and Weight Management on Pregnancy Outcomes in Mobile Medical Platform
With the opening up of the two-child policy , the composition of pregnant women in China has changed significantly . The proportion of high-risk pregnant women in the elderly has increased significantly , and the risk of adverse…
- Trial name
- NCT04989634
- Testing
- Intensive dietary and weight management, Standard care
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Capital Medical University
Gestational Diabetes Mellitus, Medical Nutrition Therapy
Characteristic and Modulation of Gut Microbiota on the Consequences of Pregnancy
Since the incidence of maternal obesity and gestational diabetes mellitus (GDM) is on the rise globally, how to improve the intrauterine environment of the offspring and prevent obesity and metabolic diseases from the early life…
- Conditions
- Gestational Diabetes Mellitus, Medical Nutrition Therapy, Overweight/Obese, Gut Microbiota
- Trial name
- NCT04190511
- Testing
- Prebiotic-containing dairy, Dietary intervention
- Where
- China
- Volunteers
- 375 people
- Sponsor
- Capital Medical University
Hyperventilation, Traumatic Brain Injury
Treatment of Spontaneous Hyperventilation With Remifentanil in Traumatic Brain Injury Patients
Spontaneous hyperventilation is common in severe traumatic brain injury patients and correlates closely with poor outcomes. How to treat this pathological condition remain unsolved.
- Trial name
- NCT04974060
- Testing
- Remifentanil Injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Polycystic Ovary Syndrome, Overweight and Obesity
Lifestyle Intervention in Pregnant Women With PCOS
Polycystic ovarian syndrome (PCOS) is the most common reproductive disorder in women of childbearing age and is also associated with metabolic abnormalities including obesity, type 2 diabetes, dyslipidemia, etc.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Gestational Diabetes
- Trial name
- NCT04216485
- Testing
- Intensive Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Capital Medical University
Neurosurgery
Driving Pressure in Neurosurgery
The effect of driving pressure (DP)-guided positive end expiratory pressure (PEEP) on early postoperative pulmonary ventilation is to be determined for patients undergoing neurosurgery.
- Trial name
- DPNS (NCT04421976)
- Testing
- PEEP
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Capital Medical University
Laparoscopy
Driving Pressure in Laparoscopic Surgery
The effect of driving pressure (DP)-guided positive end expiratory pressure (PEEP) on early postoperative pulmonary ventilation is to be determined for patients undergoing laparoscopic surgery.
- Trial name
- DPPVL (NCT04374162)
- Testing
- PEEP
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Capital Medical University
Moyamoya Disease
Safety and Efficacy of Remote Ischemic Conditioning Combined EDAS on Ischemic Moyamoya Disease
Encephaloduroarteriosynangiosis (EDAS) is widely used as an indirect technique for treatment of moyamoya disease. Nevertheless, this indirect surgery tends to establish insufficient collateral circulation in most adult MMD…
- Trial name
- RIC-IMD (NCT04917003)
- Testing
- RIC plus EDAS, EDAS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Hyperventilation, Aneurysmal Subarachnoid Hemorrhage
Drug Intervention of Spontaneous Hyperventilation in Patients With Aneurysmal Subarachnoid Hemorrhage
Although spontaneous hyperventilation patients with aneurysmal subarachnoid hemorrhage closely associated with poor outcomes, the standard therapy remains unavailable.
- Conditions
- Hyperventilation, Aneurysmal Subarachnoid Hemorrhage, Cerebral Blood Flow
- Trial name
- NCT04940273
- Testing
- Remifentanil Injection [Ultiva]
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Intrauterine Adhesion
Three-dimensional Ultrasound Applying in Assessment of Intrauterine Adhesions
In this prospective, multicenter, large-scale study，the investigators wish to examine the accuracy of several three-dimensional ultrasound anatomical and vascular parameters in diagnosing IUA when compared to the gold standard of…
- Trial name
- NCT04930913
- Testing
- Three-dimensional Ultrasound
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Intracerebral Hemorrhage Lobar, Cerebral Amyloid Angiopathy
Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage
Cerebral amyloid angiopathy-related intracerebral (CAAH) hemorrhage is second factor of primary intracerebral hemorrhage. However, no effective prevention and treatment strategies have been established.
- Trial name
- RIC-CAAH (NCT04757597)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Diuretic Abuse
Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Background.The objective of the present study is to verify whether using diuretics will improve either blood pressure or fluid overload in maintenance hemodialysis patients with residual diuresis kidney function.
- Trial name
- NCT04182854
- Testing
- Furosemid hydrochlorothiazide
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Cerebral Small Vessel Diseases
Remote Ischemic Conditioning on Cerebral Small Vessel Disease
This trial is a randomized, controlled, single-center, double-blind trial. Cerebral small vessel disease (CSVD) patients will be recruited and randomized into RIC or control group.The protective effect of remote ischemic…
- Trial name
- RIC-SVD (NCT04816500)
- Testing
- Automatic ischemic conditioning treatment instrument, Regular treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Moyamoya Disease
The Safety and Efficacy of RIC on Adult Moyamoya Disease
There are a series of symptoms such as ischemic stroke、transient ischemic attack 、hemorrhagic stroke、headache 、seizure and so on in moyamoya disease( MMD) patients .Nowadays, revascularization is the only effective way for…
- Trial name
- RIC-AMD (NCT04012268)
- Testing
- RIC, Aspirin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Central Nervous System Diseases
Dexmedetomidine for Prevention of Postoperative Delirium After Intracranial Operation for Brain Tumor
Postoperative delirium is common after major surgery, and is associated with adverse outcomes. Systematic reviews and meta-analyses of randomized controlled trials have shown that perioperative administration of dexmedetomidine…
- Trial name
- DEPOD (NCT04399343)
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Capital Medical University
Central Nervous System Diseases
Impact Dexmedetomidine on Postoperative Delirium in Patients After Intracranial Operation for Brain Tumor
Postoperative delirium is one of the most common serious complications after major surgery and is associated with undesirable consequences.
- Trial name
- NCT04494828
- Testing
- Dexmedetomidine, Normal saline group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke
The Efficacy of Remote Ischemic Conditioning on Stroke-induced Immunodeficiency
to detect the effects of RIC on stroke-induced immunodeficiency and inflammation response in acute ischemic stroke patients
- Trial name
- RIC-SIID (NCT04069546)
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Procalcitonin, Chronic Obstructive Pulmonary Disease
A Trial of Procalcitonin in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Current antibiotic prescription for patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is generally based on the Anthonisen criteria in The Global Initiative for Chronic Obstructive Pulmonary…
- Trial name
- NCT04682899
- Testing
- procalcitonin-guided antibiotic therapy, guideline-guided antibiotic therapy
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
2,3-Bisphosphoglycerate
Effect of RIC on 2,3-BPG in Erythrocyte (RIC-BPG)
Under hypoxia or high-altitude hypoxia ,it has been found that 2,3-bisphosphoglycerate(2,3-BPG) in erythrocyte increased and facilitated oxygen release to tissues.Remote Ischemic Conditioning(RIC) can also cause hypoxic…
- Trial name
- RIC-BPG (NCT04192578)
- Testing
- remote ischemic conditioning
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Stroke, Neuroprotection
Regional Hypothermia in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke
The investigators have previous shown that regional hypothermia by the intra-arterial infusion of cold saline combined with mechanical thrombectomy in acute ischemic stroke is feasible and safe.
- Conditions
- Stroke, Neuroprotection, Hypothermia
- Trial name
- RE-HIBER (NCT04554797)
- Testing
- Regional Hypothermia
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University