Clinical trials: sponsored by Capital Medical University
Ischemic Stroke
Tirofiban for Patients Treated With Alteplase
After intravenous thrombolysis, the overall recanalization rate is 46%, and recclusion after initial recanalization occurs in 14-34%.
- Trial name
- MR TEA (NCT03357133)
- Testing
- Tirofiban, Alteplase
- Where
- 7 sites in China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Hypothermia, Stroke, Acute
Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy
To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.
- Trial name
- NCT03163459
- Testing
- selective brain cooling by cold saline perfusion, mechanical thrombectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Vertebral Venous Collaterals, Serum Uric Acid
Influencing Factors of Intracranial Hypertension in Patients With Bilateral Transverse Sinus Stenosis
Bilateral transverse sinus stenosis (BTSS) is associated with intracranial hypertension (IH). However, not every BTSS patients presented with IH. The risk factors of IH in BTSS patients remained obscure.
- Conditions
- Vertebral Venous Collaterals, Serum Uric Acid, Intracranial Hypertension, Bilateral Transverse Sinus Stenosis
- Trial name
- NCT04492332
- Testing
- standard lumbar puncture
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Capital Medical University
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke
Ischemic stroke, which is due to the occlusion of a cerebral blood vessel, comprises nearly 80-90% of all strokes. Currently, reperfusion of the salvageable tissue via thrombolytic drug or endovascular treatment is the most…
- Trial name
- REVISE-2 (NCT03045055)
- Testing
- Remote ischemic conditioning., Endovascular treatment.
- Volunteers
- 180 people
- Sponsor
- Capital Medical University
Mechanical Ventilation, Acute Respiratory Distress Syndrome
The Effect of Positive End-Expiratory Pressure on Functional Residual Capacity During Mechanical Ventilation
Although positive end-expiratory pressure (PEEP) has been widely used in mechanical ventilated patients with acute respiratory distress syndrome (ARDS), how to select the "optimal" PEEP is far from consensus.
- Conditions
- Mechanical Ventilation, Acute Respiratory Distress Syndrome, Functional Residual Capacity
- Trial name
- NCT03511651
- Testing
- PEEP
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
COVID-19, SARS-CoV-2
A Trial of Remdesivir in Adults With Mild and Moderate COVID-19
In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (SARS-CoV-2) from…
- Trial name
- NCT04252664
- Testing
- Remdesivir
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Capital Medical University
COVID-19, Remdesivir
A Trial of Remdesivir in Adults With Severe COVID-19
In December 2019, Wuhan, in Hubei province, China, became the center of an outbreak of pneumonia of unknown cause. In a short time, Chinese scientists had shared the genome information of a novel coronavirus (SARS-CoV-2) from…
- Conditions
- COVID-19, Remdesivir, SARS-CoV-2
- Trial name
- NCT04257656
- Testing
- Remdesivir
- Where
- China
- Volunteers
- 237 people
- Sponsor
- Capital Medical University
Normobaric Oxygen, Cerebral Ischemia
The Efficacy of Normobaric Oxygen on Chronic Cerebral Ischemia
Chronic cerebral ischemia (CCI) is viewed as an alarming state induced by long-term reduction in cerebral perfusion, which is associated with neurological deficits and high risk of stroke occurrence or recurrence.
- Trial name
- NCT03745092
- Testing
- normobaric oxygen, room air
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Capital Medical University
Arcuate Uterus
A Randomised Controlled Trial of Hysteroscopic Resection of Mild Septum/Arcuate Uteri.
At least 82 cases of recurrent miscarriage women with a diagnosis of arcuate uterus, confirmed by three-dimensional intra-vaginal sonography (3D-TVS) and hysteroscopy, will be recruited.
- Trial name
- NCT03384082
- Testing
- hysteroscopic treatment
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Cerebral Venous Sinus Thrombosis, Batroxobin
The Efficacy and Safety of Batroxobin Combined With Anticoagulation in Cerebral Venous Sinus Thrombosis
Our previous clinical case observations showed that batroxobin combined with anticoagulation therapy can improve the sinus recanalization rate in patients with CVST, shorten the hospital stay, and increase the neurological score…
- Trial name
- NCT04269954
- Testing
- Batroxobin combined with low molecular weight heparin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Intracerebral Hemorrhage
Remote Ischemic Conditioning for Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage (ICH) results from the rupture of small vessels damaged by chronic hypertension, amyloid angiopathy or other disease.
- Trial name
- RICH (NCT03930940)
- Testing
- remote ischemic conditioning, Regular treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Capital Medical University
Prehypertension, Remote Ischemic Conditioning
Safety and Feasibility of Remote Ischemic Conditioning on Prehypertension and Early-stage Hypertension
Nowadays, the incidence of stroke in China has reached 1.6‰, and this disease has become a primary cause of death in China. One of its major risk factors is hypertension.
- Conditions
- Prehypertension, Remote Ischemic Conditioning, Early Stage Hypertension
- Trial name
- NCT04254432
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Brain Injuries
Predictors of Weaning Outcomes for Brain Injured Patients
Brian injured patients are predisposed to various complications related to mechanical ventilation. Appropriate decision making of the weaning is crucial and validated predictive parameters are desirable.
- Trial name
- NCT02863237
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Moyamoya Disease, TIA
The Effect of RIC on TIA/Stroke in Children With Moyamoya Disease
Moyamoya disease is a common reason of transient ischemic attack (TIA) and stroke in children. Remote ischemic conditioning (RIC) has been shown to prevent recurrent stroke in intracranial arterial stenosis, but it is unclear…
- Conditions
- Moyamoya Disease, TIA, Children, Stroke
- Trial name
- RIC-PMD-1 (NCT03821181)
- Testing
- RIC group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Capital Medical University
Esophageal Cancer
Adoptive Cellular Therapy and Radiation Therapy After Surgery in Treating Patients With Esophageal Cancer
Cytokine-induced killer (CIK) cells show cytolytic activity against tumor. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT01691664
- Testing
- Only radiation therapy, Radiation therapy plus DC-CIK cellular therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Capital Medical University
Uterine Septum
Intrauterine Balloon and Postoperative Estrogen Therapy in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis
Patients who want to go TCRS will randomly divided 3 groups. In Group 1(100 patients), women received postoperative estrogen therapy.
- Trial name
- NCT02617108
- Testing
- Foley balloon
- Volunteers
- 310 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Intrauterine Adhesion
Postoperative Intermittent Intrauterine Balloon Dilatation Therapy.
In this prospective, randomized, controlled study, the investigators wish to determine the efficacy of intrauterine balloon (IUB) dilatation in the prevention of adhesion reformation when compared with the conventional management.
- Trial name
- NCT03131596
- Testing
- IUB dilatation therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Arteriovenous Fistulae
Cohort Study on A Following-up System of Native Arteriovenous Fistulae
A cohort including more than 100 maintenance hemodialysis patients will be followed up according to a certain Following-up System of Native Arteriovenous Fistulae (AVF) prospectively.
- Trial name
- NCT02880761
- Testing
- Assessment guiding surgery and puncture for AVF
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Capital Medical University
Cognitive Impairment, Hemodialysis Complication
The Cohort Study of Cognitive Impairment in Chinese Hemodialysis Patients
This study is going to apply neuropsychological battery tests to measure cognitive function across multiple cognitive domains in our cohort of 600 maintenance hemodialysis patients and evaluate: 1.
- Conditions
- Cognitive Impairment, Hemodialysis Complication, Outcome, Neuropsychological Tests
- Trial name
- CODE (NCT03251573)
- Testing
- cognitive impairment
- Where
- China
- Volunteers
- 613 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Intensive Care Unit
Practice of Sedation and Analgesia in Patients With Severe Brain Injury in China
Sedation and analgesia is necessary management for patients in the intensive care units. The high-level studies of sedation and analgesia in China are still deficient, especially in patients with brain injuries who even have been…
- Trial name
- NCT03975751
- Testing
- The Glasgow Coma Scale (GCS)
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Capital Medical University