Clinical trials: sponsored by Capital Medical University
Neurogenic Dysphagia, Tracheotomy Patients
Evaluating the Effects of Intermittent Oro-esophageal in Tracheotomy Patients With Neurogenic Dysphagia
Neurogenic dysphagia refers to swallowing disorders caused by the damage of swallowing central or peripheral nerves and muscles.
- Trial name
- NCT06791590
- Testing
- intermittent oro-esophageal, Naso-intestinal tube nutrition support
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Capital Medical University
Ischemic Stroke
A Study of Probiotics in Patients With Acute Ischemic Stroke
The primary objective of this study is to evaluate the effect of daily oral administration of the probiotic supplement OMNi-BiOTiC® SR-9 for 90 days, compared to placebo, on gut microbiome beta diversity in patients aged 60 years…
- Trial name
- PRO-STROKE (NCT07651332)
- Testing
- probiotic supplement OMNi-BiOTiC® SR-9
- Volunteers
- 220 people
- Sponsor
- Capital Medical University
Effect of Drug, Adverse Drug Event
Efficacy and Safety of Remimazolam Besylate for Sedation in Post-Non-Cardiac Surgery Patients Requiring Mechanical Ventilation
A multi-center, prospective, randomized, double-blind, active-controlled, no-inferiority clinical trial conducted across 5 tertiary medical centers in China.
- Conditions
- Effect of Drug, Adverse Drug Event, Mechanical Ventilation Complication, Critical Illness
- Trial name
- NCT06575530
- Testing
- Remimazolam Besylate, Dexmedetomidine Hydrochloride
- Where
- China
- Volunteers
- 306 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Cerebral Venous Sinus Thrombosis, Deep Cerebral Vein Thrombosis
Cerebral Venous Thrombosis Cohort Study in China Mainland
This study was aimed to reveal the clinical features,natural history of the diseases and current therapeutic situations of cerebral venous thrombosis (CVT) in China mainland.
- Conditions
- Cerebral Venous Sinus Thrombosis, Deep Cerebral Vein Thrombosis, Cortical Vein Thrombosis
- Trial name
- CCC (NCT03919305)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Capital Medical University
Dry Eye
Development and Evaluation of an Intelligent Diagnosis System for Dry Eye Disease Based on Confocal Microscopy
Dry eye disease is a major ophthalmic health issue that severely affects the visual function and quality of life of the national population.
- Trial name
- NCT07614347
- Volunteers
- 75 people
- Sponsor
- Capital Medical University
Prolonged Mechanical Ventilation, Ventilator Weaning
Standardized Tracheostomy Weaning Protocol for Prolonged Mechanical Ventilation
This study evaluated the feasibility and clinical outcomes of a standardized weaning protocol for tracheostomized patients requiring prolonged mechanical ventilation.
- Conditions
- Prolonged Mechanical Ventilation, Ventilator Weaning, Tracheostomy
- Trial name
- NCT06642714
- Testing
- Standardized Stepwise Weaning Protocol
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Capital Medical University
Intestinal Tuberculosis
A 15-year Cohort Study on Risk Factors of Mortality in Patients With Intestinal Tuberculosis
This study adopts a combined design of retrospective cohort study followed by prospective observational study, which is conducted at Beijing Chest Hospital.
- Trial name
- NCT07575061
- Testing
- Observational
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beijing Chest Hospital, Capital Medical University
Acute Ischemic Stroke, Cerebral Autoregulation
Ultra-early Identification of Futile Recanalization After Reperfusion Therapy in Acute Ischemic Stroke Based on Cerebral Autoregulation
This multicenter, prospective, observational diagnostic accuracy study enrolls patients undergoing thrombectomy with intraoperative cerebral autoregulation monitoring and follows them up at predefined time points up to 90 days…
- Trial name
- CAREFUL-CA (NCT07556068)
- Testing
- diagnostic accuracy study
- Where
- 4 sites in China
- Volunteers
- 129 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Prolonged Mechanical Ventilation, Respiratory Failure
EIT-Guided Respiratory Physiotherapy for Prolonged Mechanical Ventilation (PMV)
Patients with prolonged mechanical ventilation (PMV) frequently experience impaired ventilation distribution, respiratory muscle dysfunction, secretion retention, and delayed liberation from mechanical ventilation.
- Conditions
- Prolonged Mechanical Ventilation, Respiratory Failure, Critical Illness
- Trial name
- PMV (NCT07372794)
- Testing
- EIT-Guided Respiratory Physiotherapy, Conventional Respiratory Physiotherapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
High Flow Oxygen Therapy, Neuro ICU
HFTO Via Tracheal Intubation in Neurocritical Patients
Neurocritical patients often require prolonged invasive ventilation due to impaired respiratory drive and airway protection deficits.
- Trial name
- NCT07257016
- Testing
- HFTO, PSV
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Capital Medical University
Hypertension
Efficacy of Remote Ischemic Conditioning for Hypertension in High-Altitude Immigrant Populations
This study is a multicenter, prospective, randomized, open-label, parallel-controlled clinical trial. The study participants are adult patients with hypertension who have been long-term residents (for >6 months) in high-altitude…
- Trial name
- NCT07562477
- Testing
- RIC
- Volunteers
- 184 people
- Sponsor
- Capital Medical University
Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation
Evaluation Criteria, Diagnostic Criteria, Surgical Indications, and Establishment of Surgical Standards for "Cerebral Tinnitus Syndrome" Caused by Internal Jugular Vein Stenosis.
"Cerebral Tinnitus," also known as "cranial tinnitus," refers to the patient-reported perception of intracranial sounds. It often presents as "Cerebral Tinnitus Syndrome," which includes symptoms such as tinnitus with hearing…
- Conditions
- Jugular Vein Anomaly (Disorder), Diagnostic Self Evaluation, Nerosurgery, Assessment, Self
- Trial name
- NCT07560280
- Testing
- Atlas Transverse Process Mastoidectomy with Lysis and Perfusion
- Where
- China
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
High Altitude Polycythemia
Remote Ischemic Conditioning for High Altitude Polycythemia in High-Altitude Immigrant Populations
This study is a multicenter, prospective, randomized, open-label, parallel-controlled clinical trial. The participants are adult patients with high-altitude polycythemia who have been long-term residents (for >6 months) in…
- Trial name
- NCT07562464
- Testing
- RIC
- Volunteers
- 222 people
- Sponsor
- Capital Medical University
Anxiety, Prolonged Mechanical Ventilation
Effects of Music Therapy on Anxiety Symptoms in Patients With Prolonged Mechanical Ventilation: A Randomized Controlled Trial
The purpose of this study is to evaluate the effects of music therapy on anxiety symptoms in patients requiring prolonged mechanical ventilation (PMV).
- Trial name
- NCT07560384
- Testing
- Patient-Directed Music Therapy (PDMT), Environmental Control and Matched Interaction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Acute, Myocardial Injury
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Myocardial Injury Following Acute Ischemic Stroke
Introduction: The management of acute myocardial injury following acute ischemic stroke (AMI-AIS), a frequent complication that severely worsens prognosis, is challenging.
- Trial name
- NCT07531394
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 580 people
- Sponsor
- Capital Medical University
Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation
Clinical Application of Low-Field Magnetic Resonance Imaging in Patients on Extracorporeal Cardiopulmonary Resuscitation
Timely identification of acute brain injury (ABI) patterns in patients with extracorporeal cardiopulmonary resuscitation (ECPR) is essential for prognostic assessment and optimization of clinical management, particularly…
- Conditions
- Cardiac Arrest (CA), Extracorporeal Cardiopulmonary Resuscitation, Acute Brain Injury
- Trial name
- NCT07526701
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Capital Medical University
Breast Neoplasms, Syndrome
Development and Usability Evaluation of a Knowledge Graph-Based Symptom Management System for Patients With Breast Cancer Undergoing Chemotherapy
Patients with breast cancer patients undergoing chemotherapy commonly experience multiple co-occurring symptoms that are dynamic, interrelated, and difficult to manage using conventional approaches.
- Trial name
- KG-SMR-BC (NCT07495358)
- Testing
- Knowledge Graph-Based Symptom Management System
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Alzheimer Disease
Study on Biomarkers for Early Diagnosis of Alzheimer's Disease
The project of Bio-AD is a population- based cohort study among the elderly in China. The project includes not only Alzheimer's disease (AD including familial AD and sporadic AD), but also other clinical stage of AD, as well as…
- Trial name
- NCT04575337
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Vascular Dementia
Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia
Butylphthalide soft capsule has been confirmed to have beneficial effects for patients with vascular dementia (VaD) in clinical trial of phase II study.
- Trial name
- NCT03804229
- Testing
- Butylphthalide soft capsule
- Where
- China
- Volunteers
- 707 people
- Sponsor
- Capital Medical University
Influenza
Suraxavir Marboxil And Oseltamivir for Influenza Prophylaxis Under a Hospital-based Setting
This study aims to evaluate the efficacy of antiviral prophylaxis in preventing in-hospital influenza transmission. We will enroll hospitalized patients with confirmed influenza (index cases) and their uninfected roommates (room…
- Trial name
- NCT07236814
- Testing
- Suraxavir marboxil, Oseltamivir
- Where
- 2 sites in China
- Volunteers
- 384 people
- Sponsor
- Capital Medical University