Clinical trials: sponsored by Capital Medical University
Obstructive Sleep Apnea
Clinical Characteristics and Molecular Mechanism of Patients With Obstructive Sleep Apnea
To clarify the clinical features of patients with obstructive sleep apnea; To construct a multi-omics database of patients with obstructive sleep apnea, and compare the effects of different degrees of sleep apnea on prognosis…
- Trial name
- NCT07277608
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Ischemic Stroke
Normobaric Oxygen in AIS Transferred for EVT
The primary objective of this study is to estimate the efficacy and safety of NBO on 3-month functional outcome after acute ischemic stroke
- Trial name
- AN-O2 (NCT06666764)
- Testing
- NBO, Control
- Where
- 112 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke, Anterior Circulation Brain Infarction
Remote Ischemic Conditioning for Acute Ischemic Stroke Treated With Mechanical Thrombectomy（RECAST-MT）
For patients with acute ischemic stroke caused by large vessel occlusion, endovascular thrombectomy has been demonstrated to be the most effective therapy, as approximately 90% of the occluded vessels can be recanalized.
- Trial name
- RECAST-MT (NCT06559241)
- Testing
- 14-day remote ischemic conditioning, 30-day remote ischemic conditioning, Endovascular thrombectomy
- Where
- 56 sites in China
- Volunteers
- 2,105 people
- Sponsor
- Capital Medical University
Locally Advanced Non-small Cell Lung Cancer
RAPART in Locally Advanced Non-small Cell Lung Cancer Patients
This is a Phase II/III randomized clinical trial of Radiosensitivity-Assisted Personalized Adaptive Radiotherapy Technology (RAPART) in locally advanced non-small cell lung cancer patients.
- Trial name
- NCT07164885
- Testing
- Radiosensitivity-Assisted Personalized Adaptive Radiotherapy Technology（RAPART)）, Conventional radiotherapy
- Where
- China
- Volunteers
- 911 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Transient Ischemic Attack
Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis
The objective of this study is to evaluate the effectiveness and safety of regular physical exercise in preventing ischemic stroke events in patients with symptomatic intracranial arterial stenosis.
- Trial name
- RESIST (NCT06615726)
- Testing
- Regular physical exercise, Control group
- Where
- 58 sites in China
- Volunteers
- 1,300 people
- Sponsor
- Capital Medical University
Prolonged Mechanical Ventilation
Effects of IMT on Weaning and Diaphragmatic Function in PMV Patients
Prolonged mechanical ventilation (PMV) and weaning failure can lead to extended hospital stays, as well as increased morbidity and mortality during hospitalization.
- Trial name
- NCT07200037
- Testing
- inspiratory muscle training
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Acute Respiratory Tract Infection
PCOT for Outpatients With Acute Respiratory Tract Infection at Risk of Severe Disease in Primary Healthcare
This study aims to evaluate the clinical value of point-of-care multiplex PCR testing (POCT) in guiding early diagnosis and target treatment for acute respiratory infections in primary healthcare settings.
- Trial name
- NCT07159230
- Testing
- point-of-care multiplex PCR test
- Where
- China
- Volunteers
- 16,868 people
- Sponsor
- Capital Medical University
Mood Disorders, Suicidal Ideation
Esketamine vs ECT for Acute Suicidality
This study is a multicenter, randomized, non-inferiority, parallel-group clinical trial designed to evaluate the efficacy and safety of esketamine compared with electroconvulsive therapy (ECT) in the treatment of suicidal…
- Conditions
- Mood Disorders, Suicidal Ideation, Depressive Episode
- Trial name
- NCT06355180
- Testing
- Esketamine, Electroconvulsive therapy
- Where
- 6 sites in China
- Volunteers
- 340 people
- Sponsor
- Capital Medical University
Cardiac Arrest (CA)
Effect of Target Temperature Management on Intestinal Flora and Its Metabolites in Patients With Cardiac Arrest
Based on the self-control design, this study explored the dynamic regulation of target temperature management therapy (TTM) on intestinal flora structure and metabolites of patients after cardiopulmonary resuscitation (CPR).
- Trial name
- NCT06974682
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Capital Medical University
Basilar Artery Occlusion, Ischemic Stroke
Basilar Artery Occlusion Chinese Endovascular Trial in Patients With Large Core Infarct
This study evaluates the safety and efficacy of endovascular therapy for acute basilar artery occlusion with large core infarcts in a multicenter randomized trial.
- Conditions
- Basilar Artery Occlusion, Ischemic Stroke, Large Core Infarct
- Trial name
- BAOCHE3 (NCT07046299)
- Testing
- Endovascular Therapy Plus Best Medical Treatment, Best Medical Treatment Alone
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Capital Medical University
Influenza
Severe Influenza Trial of ARbidol
This is a multicenter, randomised, double-blind, controlled study to assess the efficacy and safety of arbidol plus oseltamivir, compared with oseltamivir alone in approximately 200 hospitalized adults and adolescent patients…
- Trial name
- STAR (NCT03787459)
- Testing
- Arbidol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Capital Medical University
Retained Products of Conception, Miscarriage
A Prospective Study Evaluating the Impact of Conservative Management on Retained Products of Conception and EMV
The goal of this observational study is to learn about the therapeutic effects of the conservative treatment approach on pepole with retained products of conception (RPOC) and Enhanced myometrial vascularity (EMV).
- Conditions
- Retained Products of Conception, Miscarriage, Conservative Management
- Trial name
- NCT06862089
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
High Altitude
The Study of Personalized Health Check-up Programs and Standards for High-altitude Migrant Populations
By using wearable devices to monitor and record the physiological data changes and health outcomes (incidence and severity of high-altitude illnesses) of high-altitude migrants at different stages (pre-entry, acute/chronic…
- Trial name
- NCT07018193
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Schizophrenia, Bipolar Disorder
App and Body Fat Scale in the Management of Overweight Patients
This study tests whether using a health app (Huawei Health) and a smart body fat scale can help overweight patients with schizophrenia or bipolar disorder lose weight and stay engaged in their health. What We're Testing: 1.
- Conditions
- Schizophrenia, Bipolar Disorder, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT05866107
- Testing
- Effectiveness and Feasibility of Self-Monitoring for Weight Management in Individuals with Mental Disorders Using Digital Intervention ("SWIM" trial)
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Capital Medical University
Colorectal Cancer
Exploratory Study of Intermittent Hypoxia Intervention on Colorectal Cancer
This study aims to explore the safety and efficacy of intermittent hypoxia intervention on patients with colorectal cancer.
- Trial name
- NCT06584318
- Testing
- Intermittent hypoxia intervention
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Cesarean Scar Defect
Hysteroscopic "360°" Surgery for Improvement of Symptoms in Cesarean Scar Defects
Patients with symptomatic Cesarean Scar Defect (CSD) who are expected to undergo hysteroscopic surgery will be randomly divided into the traditional hysteroscopic "channelization" treatment group and the hysteroscopic "360 °"…
- Trial name
- NCT06917014
- Testing
- 360°, traditional
- Volunteers
- 88 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Normobaric Hyperoxia, Intracerebral Hemorrhage
Normobaric Hyperoxia for Intracerebral Hemorrhage
Perihematoma edema (PHE), as the major injury for intracranial hemorrhage (ICH) involves more than the initial tissue damage induced directly by the hematoma.
- Trial name
- NCT04144868
- Testing
- Oxygen storage face masks and nasal catheter, Nasal catheter
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Capital Medical University
Mechanical Ventilation, Neuromuscular Electrical Stimulation (NMES)
The Impact Of Respiratory Neuromuscular Stimulation On Patients With Invasive Mechanical Ventilation
Mechanical ventilation (MV) is an important treatment measure for critically ill patients in the intensive care unit (ICU). MV is widely used in the treatment of respiratory failure and is also one of the important means of life…
- Trial name
- NCT06952335
- Testing
- Phrenic nerve stimulation at 8mA, Phrenic nerve stimulation at 15mA, Phrenic nerve stimulation at 15mA combined with phrenic-abdominal stimulation at 15mA
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Capital Medical University
Tracheotomy
Speaking Valve Combined With Airway Pressure Predicts Upper Airway Patency in Adult Tracheotomized Patients
This study was aimed to evaluate whether speaking valve combined with airway pressure could predict upper airway patency non-invasively in prolonged tracheostomized patients, identify candidates who need following endoscopy…
- Trial name
- NCT06521320
- Testing
- speaking valve combined with airway pressure, Bronchoscopy
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Capital Medical University
Neurology, Emergency
Application of Large Language Models in Emergency Neurology
Emergency neurology covers a wide range of conditions, often involving urgent situations such as acute cerebrovascular diseases, seizures, central nervous system infections, and consciousness disorders.
- Trial name
- NCT06779292
- Testing
- Large Language Model Diagnosis
- Where
- China
- Volunteers
- 433 people
- Sponsor
- Capital Medical University