Clinical trials: sponsored by Capital Medical University
Non Small Cell Lung Cancer
Adebrelimab Plus Chemo and Recaticimab in Perioperative Treatment of Resectable NSCLC
Current studies confirmed that the immune perioperative treatment with combination chemotherapy curative effect and safety of resectable NSCLC, but its short-term curative effect and long-term survival benefit remains to be…
- Trial name
- NCT06467617
- Testing
- Adebrelimab plus albumin-bound paclitaxel, carboplatin and recaticimab
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Beijing Chest Hospital, Capital Medical University
Stroke, Hypothermia Treatment
Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics.
Endovascular Thrombectomy has emerged as a pivotal treatment modality for acute ischemic stroke. However, despite successful thrombus removal, a substantial proportion of patients still experience poor outcomes.
- Trial name
- NCT06665386
- Testing
- hypothermia
- Where
- China
- Volunteers
- 258 people
- Sponsor
- Capital Medical University
Alzheimer Disease
Efficacy and Safety of Wei Li Bai Capsules in the Treatment of Alzheimer's Disease
In clinical trials of preclinical pharmacodynamic studies, Wei Li Bai capsules has been proved to significantly improve the learning and memory ability of Alzheimer's disease model.
- Trial name
- NCT05670912
- Testing
- Wei Li Bai capsules
- Where
- 3 sites in China
- Volunteers
- 105 people
- Sponsor
- Capital Medical University
Ovarian Tumors
Establishment and Clinical Application of AI-based Multimodal Diagnosis System for Ovarian Tumors
Ovarian tumors are a common disease that threatens women's health. They are insidious in onset, have over ten pathological types, and exhibit diverse biological behaviors, making accurate diagnosis a key factor in clinical…
- Trial name
- NCT06703112
- Testing
- An auxiliary diagnostic model for ovarian tumors
- Volunteers
- 584 people
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University
Alzheimer Disease
Efficacy and Safety of Flos Gossypii Flavonoids Tablet in the Treatment of Alzheimer's Disease
In clinical trials of preclinical pharmacodynamic studies, Flos Gossypii Flavonoids Tablet has been proved to significantly improve the learning and memory ability of Alzheimer's disease model.
- Trial name
- NCT05269173
- Testing
- Flos gossypii flavonoids tablet
- Where
- 19 sites in China
- Volunteers
- 240 people
- Sponsor
- Capital Medical University
Difficult-to-Wean Patients
Electrical Impedance Tomography in Guiding Early and Precise Rehabilitation of Patients with Difficult Ventilator Weaning
Diaphragm dysfunction, ineffective chest wall and respiratory muscle function are frequently observed in critically ill patients with difficult weaning from mechanical ventilation(MV).It is the leading cause of retention of…
- Trial name
- NCT06677099
- Testing
- chest physiotherapy, EIT-guided chest physiotherapy
- Volunteers
- 80 people
- Sponsor
- Capital Medical University
Community Acquired Pneumonia
Electrical Impedance Imaging Techniques in Guiding the Use of Chest Physiotherapy in Patients with Pneumonia
In this study, electrical impedance tomography (EIT), a noninvasive and nonradiative technology, is applied to guide the accurate respiratory rehabilitation of pneumonia.
- Trial name
- NCT06642701
- Testing
- Electrical Impedance Tomography, chest physiotherapy
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Capital Medical University
Acute Stroke, Ischemic Stroke, Acute
Tirofiban for the Prevention of Early Neurological Deterioration After Intravenous Thrombolysis in Acute Ischemic Stroke
A prospective, multicenter, randomized, controlled, open-label, blinded endpoint trial to evaluate the safety and efficacy of intravenous administration of tirofiban for preventing early neurological deterioration after…
- Conditions
- Acute Stroke, Ischemic Stroke, Acute, Cerebral Infarction
- Trial name
- TREND-2 (NCT06587347)
- Testing
- Tirofiban Hydrochloride, Standard medical treatment (SMT)
- Where
- China
- Volunteers
- 302 people
- Sponsor
- Capital Medical University
Diabetic Kidney Disease (DKD)
Remote Ischemic Conditioning for the Treatment of Diabetic Kidney Disease
Chronic kidney disease (CKD) is a growing epidemic affecting 10% of the population worldwide. Significantly, diabetic kidney disease (DKD) is the main cause of CKD and affects approximately 40% of patients with diabetes.
- Trial name
- RIC-DKD (NCT06654921)
- Testing
- Remote ischemic conditioning, Standard medication therapy
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Cardiac Arrest, Brain Injuries
Functional MRI to Assess Brain Damage in Cardiac Arrest Patients
This is a single-center, observational study. Patients after successful cardiopulmonary resuscitation (CPR) will be transferred to the emergency intensive care unit for further standardized management.
- Trial name
- NCT05966389
- Testing
- No interventions
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Capital Medical University
Lung Cancer (NSCLC)
Association Between Microbiome and the Efficacy and Safety of PD-1/PD-L1 Blockade in Resectable NSCLC
This study will investigate the relationship between respiratory and gut microbiome and PD-1/PD-L1 immune checkpoint inhibitor efficacy and immune-related adverse events (irAE) in patients with non-small cell lung cancer (Stage…
- Trial name
- NCT06613308
- Testing
- Neoadjuvant immunotherapy combined with chemotherapy, Neoadjuvant chemotherapy
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Acute Ischemic Stroke, Basilar Artery Occlusion
Basilar Artery Occlusion Chinese Endovascular Trial in the Extended Time Window
A prospective, multi-center, randomized, controlled, open-label, blinded-endpoint trial to evaluate the safety and efficacy of endovascular mechanical thrombectomy for acute basilar artery occlusion in the extended time window
- Trial name
- BAOCHE2 (NCT06560203)
- Testing
- Mechanical thrombectomy
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Capital Medical University
Moyamoya Disease, Pediatric
Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy
Revascularization surgery has been the standard treatment to prevent ischemic stroke in pediatric Moyamoya disease (MMD) patients with ischemic symptoms.
- Trial name
- RIC-PMD (NCT03546309)
- Testing
- RIC group, Medication group
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University
Dental Implantation, Guided Bone Regeneration
Effects of the SIS Membrane on GBR and Early Loading of Maxillary Anterior Dental Implants
The aim of this randomized controlled trial (RCT) is to determine whether early implant loading that shortens the healing period to 6 weeks can be safely and effectively applied to implants with good initial stability in the…
- Trial name
- NCT06574815
- Testing
- Early implant loading, Delayed implant loading, GBR using an SIS membrane
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Beijing Stomatological Hospital, Capital Medical University
Acute Exacerbation of COPD, Corticosteroid
Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels
Chronic Obstructive Pulmonary Disease (COPD) is one of the top three causes of death worldwide now. Acute exacerbations (AEs) of COPD are a risk factor for lung function deterioration, poor quality of life, longer…
- Conditions
- Acute Exacerbation of COPD, Corticosteroid, Morality, Lung Diseases, Obstructive
- Trial name
- NCT05059873
- Testing
- Prednisone
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Capital Medical University
Cardiometabolic Risk, Visceral Fat
Visceral Fat and Cardiometabolic Risk
The present study showed that the 75th percentile of visceral fat area in boys and girls is the optimal cutoff for screening cardiometabolic risk and its clustering, but the 80th percentile is the optimal cutoff for hyperglycemia…
- Conditions
- Cardiometabolic Risk, Visceral Fat, Cohort Study
- Trial name
- NCT06554262
- Testing
- No intervention
- Volunteers
- 18,938 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Stroke, Endovascular Treatment
Normobaric Hyperoxia Combined With Endovascular Treatment for Acute Ischemic Stroke
The purpose of this study is to evaluate the safety and efficiency of normobaric hyperoxia combined with endovascular treatment for acute ischemic stroke patients with stroke onset 6-24 hours.
- Conditions
- Stroke, Endovascular Treatment, Neuroprotection
- Trial name
- NCT05128422
- Testing
- Normobaric oxygen therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Geriatric Depression, Cognitive Impairment
Electronic Training of Elderly Depression With Cognitive Impairment
late-life depression (LLD) is the most common mental illness in the elderly. Due to the increasing prevalence of population aging, it has become one of the important factors affecting the quality of life of the elderly.
- Trial name
- NCT05588102
- Testing
- Selective Serotonin Reuptake Inhibitor（SSRIs，Fluoxetine, paroxetine, fluvoxamine, sertraline, citalopram, escitalopram）
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Capital Medical University
Depression, Obesity
Implementation Research on the Intervention Mode of " Comorbidity-Co-causes-Joint-prevention" Comprehensive Demonstration District of Depression and Obesity Among Children and Adolescents in Beijing
Depression and obesity have become the most prominent health problems among adolescents and have caused a heavy burden on the health and social economy of the whole population.
- Conditions
- Depression, Obesity, High Risk of Depression, Overweight
- Trial name
- NCT06489990
- Testing
- combination intervention strategy of [Comorbidity-Co-causes-Joint-prevention], routine health education and mental health knowledge
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Capital Medical University
COVID-19 Pneumonia
Pirfenidone in Adult Hospitalized Patients With COVID-19
This center intends to conduct a multicenter, randomized, placebo-controlled study to evaluate the effectiveness and safety of Nintedanib ethanesulfonate soft capsule in the treatment of pulmonary fibrosis in patients with…
- Trial name
- NCT05713292
- Testing
- Pirfenidone Oral Product
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Capital Medical University