Clinical trials: sponsored by Case Comprehensive Cancer Center
Malignant Neoplasm, Cancer
Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
The goal of this clinical trial is to learn if the use of virtual reality during chemotherapy treatment helps participants achieve an improvement in distress, which may include unpleasant experience, anxiety, depression and/or…
- Trial name
- NCT06446115
- Testing
- Virtual Reality, Preferred activity, Questionnaires
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Robotic Telesurgery in Urology
The goal of this clinical trial is to confirm the safety and feasibility of robotic telesurgery when used for the surgical management of prostate cancer in participates undergoing treatment for prostate cancer.
- Trial name
- NCT07541066
- Testing
- High-Intensity Focused Ultrasound (HIFU) robotic device
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum
The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors
The purpose of this research study is to determine whether testing of stool for a panel of markers will enable us to detect polyps and cancer compared to standard testing.
- Conditions
- Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Stage I Colorectal Cancer, Stage II Colorectal Cancer
- Trial name
- NCT04624555
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Case Comprehensive Cancer Center
Treatment With Proton Beam Radiation Therapy
Proton Therapy Patient Registry
The purpose of this study is to establish a database (or "registry") of patients treated with proton beam therapy at the University Hospitals (UH) Proton Therapy Center.
- Trial name
- NCT02986048
- Testing
- Proton Beam Therapy
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Cleveland African American Prostate Cancer Project
The purpose of this research is to test intervention strategies that encourage and support Black or African American men who are 40 and older to complete prostate cancer screening, and specifically to complete a prostate-specific…
- Trial name
- NCT05469269
- Testing
- Passive Education, Education by Community Navigator, Education at Community Outreach Screening Event
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Effectiveness of AI Genetic Counseling Program vs In-person Genetic Counseling in Breast Cancer
The purpose of this study is to help better understand the uptake and impact of genetic testing for women diagnosed with breast cancer who do not meet National Comprehensive Cancer Network (NCCN) criteria for genetic testing.
- Trial name
- NCT04354675
- Testing
- Automated program (ChatBot), Genetics counselor, BCGCKQ Survey
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients
The purpose of this study is to learn whether an education and support program can help caregivers feel more confident in technical and communication skills needed to care for a person with cancer.
- Trial name
- NCT04055948
- Testing
- One-on-one support/educational sessions, Telephone booster contact
- Where
- 2 sites in United States
- Volunteers
- 484 people
- Sponsor
- Case Comprehensive Cancer Center
Somatic Mutation
Linking Somatic Mutation Rate With Baseline Exposure in East Palestine
The goal of this study is to This research team is conducting this study to develop methods to measure the biological impact of exposure to the chemicals released following the February 3, 2023 train derailment on residents of…
- Trial name
- NCT06357845
- Testing
- Survey, Biological specimen collection, Communications about study updates and future research opportunities
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Barrett's Esophagus
Detection of Barrett s Esophagus in Patients Without GERD Symptoms
The purpose of this study is to develop a method to detect Barrett's esophagus (BE) in individuals with a new office-based diagnostic test.
- Trial name
- NCT04880044
- Testing
- EsoCheck/EsoGuard (EC/EG), Esophago-gastro-duodenoscopy (EGD)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Case Comprehensive Cancer Center
Skin Cancer, Skin Carcinoma
Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery
This study aims to improve patient comfort by exploring the potential of lavender aromatherapy in reducing anxiety and unpleasant odor perception during Mohs Micrographic Surgery (MMS).
- Trial name
- NCT06167096
- Testing
- Lavender essential oil, Water
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Case Comprehensive Cancer Center
Colorectal Cancer
Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans
The burden of colorectal cancer (CRC) is unequal among various populations within the United States. This inequality is most notable among African Americans, who exhibit the highest CRC mortality of all US populations.
- Trial name
- NCT03640208
- Testing
- Education presented by trained caregiver
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Prostate Cancer
Patient Recall of Cancer Screening and Diagnosis
The purpose of this research is to try to better understand how much information relating to cancer screening and diagnoses that people can recall on their own and to better understand how to help people get better information.
- Trial name
- NCT05014295
- Testing
- Accessing personal medical records online via online portals
- Sponsor
- Case Comprehensive Cancer Center
Glioblastoma
Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma
This study involves participants with recurrent glioblastoma brain tumors (GBM). This means that a participant's brain tumor has either returned after being treated by a previous therapy, or has continued to progress despite…
- Trial name
- NCT02669173
- Testing
- Capecitabine, Bevacizumab
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Case Comprehensive Cancer Center
Actinic Keratoses
Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses
The purpose of the study is to test a new video device for actinic keratoses. The device takes images of your skin lesions during the treatment, to learn whether this device can predict how well the treatment is working.
- Trial name
- NCT05923060
- Testing
- Topical Aminolevulinate, Photodynamic therapy (PDT), Red light illumination
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Node-positive Breast Cancer
Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients
Lymphedema is a devastating complication of breast cancer surgery that decreases the quality of life of up to 40% of breast cancer survivors.
- Trial name
- NCT05970107
- Testing
- Axillary Lymph Node Dissection, Axillary Reverse Mapping, Lymphaticovenous Bypass
- Volunteers
- 400 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer
The purpose of this study is to examine the impact of Mediterranean-type diets on the metabolism of men with localized prostate cancer.
- Trial name
- NCT05590624
- Testing
- Lower-Carbohydrate Med-t-Diet, Low-Fat Med-t-Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Case Comprehensive Cancer Center
Hepato Cellular Carcinoma (HCC)
BC3402 w/ Tremelimumab + Durvalumab (STRIDE) in Hepatocellular Carcinoma
The purpose of this study is to test the safety and efficacy of an investigational (experimental) product called BC3402. This product is considered experimental because it is not approved by the U.S.
- Trial name
- NCT06608940
- Testing
- BC3402, Durvalumab, Tremelimumab
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Lung Cancer, Left Sided Breast Cancer
A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
Data collection and assessment on patients with left-sided breast cancer or undergoing lung stereotactic body radiation therapy (SBRT) utilizing continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT05142358
- Testing
- Continuous Positive Airway Pressure, Deep inspiratory breath hold, Free Breath
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Depression, Cancer
Mindfulness-based Intervention for Depressive Symptoms Sent Via Text (MINDSET)
The purpose of this study is to develop and test a new intervention to reduce depressive symptoms in post-treatment cancer participants.
- Conditions
- Depression, Cancer, Stage III Breast Cancer, Stage II Breast Cancer
- Trial name
- NCT06811454
- Testing
- MINDSET, Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Case Comprehensive Cancer Center
Pancreatic Ductal Adenocarcinoma, Periampullary Cancer
Escitalopram to Placebo in Patients With Localized Pancreatic Cancer
Use of antidepressants for participants with localized pancreatic and periampullary cancer receiving neoadjuvant therapy.
- Trial name
- NCT05289830
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Case Comprehensive Cancer Center