Clinical trials: sponsored by Cedars-Sinai Medical Center
Incontinence, Urinary
A Prospective Case Series Analysis of Initial Users of the Urovac Device
To document usage of the Urovac device among 30 initial users of the device in an acute rehabilitation facility, with analysis of whether and how patients benefitted, challenges encountered, and how benefits and challenges varied…
- Trial name
- NCT03872518
- Testing
- Urovac
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Liver Cirrhosis, Alcoholic
Feasibility of Wearable Biosensors for Monitoring Daily Activity, Heart Rate, and Sleep Among Patients With Decompensated Cirrhosis
In this protocol, the investigators will determine compliance, acceptability, and patient satisfaction regarding the use of remote monitors and summarize changes in activity over time among patients with decompensated cirrhosis.
- Trial name
- NCT06057870
- Testing
- Application on Apple watch
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Rotator Cuff Tears, Rotator Cuff Injuries
The Effect of Cross-Education on Shoulder Arthroscopy
The purpose of this study is to examine the effectiveness of a strength training protocol on the uninjured upper extremity either alone or with the addition of blood flow restriction (BFR) training on subjects who have undergone…
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Repair
- Trial name
- NCT04470570
- Testing
- Cross-Education, Blood-Flow Restriction Training
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Cedars-Sinai Medical Center
Rotator Cuff Tears
The Effect of Mindfulness/Meditation on Post-operative Pain and Opioid Consumption
The objective of this study is to examine the effectiveness of mindfulness/meditation using the Headspace App on post-operative pain and opioid consumption in patients after arthroscopic rotator cuff repairs, biceps tenodesis…
- Trial name
- NCT04855968
- Testing
- In addition to standard post-op medication patient will have access to the head space meditation application., Patients will take standard post-op pain medication
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
COVID-19
Clazakizumab (Anti-Interleukin 6 (IL-6) Monoclonal) Compared to Placebo for Coronavirus Disease 2019 (COVID-19)
This is a single center, randomized, double-blind, placebo-controlled, exploratory phase II study enrolling 60 patients. We propose the administration of a blinded dose of an investigational product (IP) (clazakizumab or placebo…
- Trial name
- NCT04348500
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Cedars-Sinai Medical Center
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
MS-ResearchBiomarkerS
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MS-ReBS (NCT05204459)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Irritable Bowel Syndrome
Elemental Diet and Gut Microbiome
he primary objective of this study is to assess changes in stool microbiome profiles in patients after an elemental diet.
- Trial name
- NCT05978973
- Testing
- Elemental Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Pancreatitis, Pancreas Cancer
Contrast Enhanced Endoscopic Ultrasound in Pancreas Lesions
The purpose of this study is to determine whether quantitative contrast-enhanced endoscopic ultrasound (CE-EUS) improves the evaluation of pancreas tumors and precursor lesions, including cysts, compared to conventional…
- Conditions
- Pancreatitis, Pancreas Cancer, Pancreas Cyst
- Trial name
- NCT04324294
- Testing
- EUS enhanced with contrast to evaluate pancreas
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Anorectal Disorder
Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery
The purpose of the study is to evaluate whether being randomized to an aggressive postoperative non-narcotic pain regimen that treats pain from multiple different pathways may decrease postoperative pain levels, decrease…
- Trial name
- NCT03738904
- Testing
- ERAS, Standard of care
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Preeclampsia, Severe Preeclampsia
Complement Regulation to Undo Systemic Harm in Preeclampsia
This is a Phase II, single arm, open-label study to determine if treatment with eculizumab prolongs pregnancy compared to historical controls in women with preeclampsia between 23-30 weeks gestation.
- Conditions
- Preeclampsia, Severe Preeclampsia, Eculizumab, HELLP
- Trial name
- CRUSH (NCT04725812)
- Testing
- Eculizumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cedars-Sinai Medical Center
Medication Errors, Patient Safety
Safety Action Feedback and Engagement (SAFE) Loop
This trial will test whether a new intervention, the Safety Action Feedback and Engagement (SAFE) Loop, enhances nurse incident reporting practices, improves nurses' perceptions of incident reporting, and lowers rates of…
- Trial name
- NCT05381441
- Testing
- Safety Action Feedback and Engagement (SAFE) Loop
- Where
- United States
- Volunteers
- 5,163 people
- Sponsor
- Cedars-Sinai Medical Center
Opioid Use, Pain, Postoperative
SMS Education for Post-operative Pain
The purpose the research is to assess whether or not postoperative education and awareness about pain and opioid use through SMS text messages will reduce overall opioid utilization after common outpatient surgeries.
- Trial name
- NCT04039191
- Testing
- SMS education, SMS survey
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Cedars-Sinai Medical Center
Tobacco Use Cessation
Feasibility, Adoption and Efficacy of A Virtual Reality Smoking Cessation Program for Patients Undergoing Lung Cancer Screening
Lung cancer is the second most common cancer and the leading cause of cancer related deaths in the United States (US . Tobacco use is the leading cause of lung cancer and tobacco control continues to be the primary method of lung…
- Trial name
- NCT06021652
- Testing
- MindCotine Virtual reality
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Amyloidosis, Immunoglobulin Light-chain
Cardiac Amyloidosis Registry Study
This registry is a observational, multi-center study designed to collect data and analyze it retrospectively on patients with cardiac amyloidosis who have been evaluated and treated at major amyloid centers across the US and…
- Trial name
- CARS (NCT05174338)
- Testing
- Registry
- Where
- 23 sites in United States, Canada
- Volunteers
- 5,000 people
- Sponsor
- Cedars-Sinai Medical Center
Heart Failure
A Pilot Study to Increase Utilization of GDMT in Patients With HFrEF
The purpose of this study is to test a clinical decision support (CDS) tool that provides clinicians (cardiologists and nurse practitioners) medication recommendations regarding guideline directed medical therapy (GDMT) in…
- Trial name
- NCT05170165
- Testing
- Using a clinical decision software to provide specific recommendation of a medication at a certain dosage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cedars-Sinai Medical Center
Healthy
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
The purpose of this research is to understand how to apply cardiac magnetic resonance imaging (CMR) to women with small artery heart disease by looking at the CMRs of women without heart disease.
- Trial name
- NCT00573339
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Heart Disease
Heart Disease of the Small Arteries in Women and Men
Women suffer disproportionately than men from Cardiac Syndrome X ( chest pain in the absence of flow limiting coronary artery stenosis). Coronary microvascular disease is hypothesized to mediate chest pain in this syndrome.
- Trial name
- NCT00573027
- Testing
- noninvasive tests
- Where
- United States
- Volunteers
- 634 people
- Sponsor
- Cedars-Sinai Medical Center
Microvascular Coronary Dysfunction
Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease
Microvascular coronary dysfunction (MCD) (abnormities in small blood vessels/arteries in heart) with symptoms of persistent chest pain, primarily impacts women.
- Trial name
- NCT02301663
- Testing
- Handgrip, Altitude simulation, Leg exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pancreatitis, Acute, Alcohol Drinking
A Case-CrossovEr Study deSign to Inform Tailored Interventions to Prevent Disease Progression in Acute Pancreatitis
The Purpose of this study is to investigate changes in alcohol consumption in the period leading up to the onset of pancreatitis and compare that to levels of drinking during asymptomatic periods.
- Conditions
- Pancreatitis, Acute, Alcohol Drinking, Health Behavior
- Trial name
- ACCESS-AP (NCT04743323)
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Cedars-Sinai Medical Center
Lung Cancer
MRI and Biomarkers for Lung Nodules Detected During Lung Cancer Screening
The primary objective of this pilot observational study is to evaluate the accrual and retention rate of a study population from a centralized lung cancer screening program to support MRI and blood-based biomarker research for…
- Trial name
- NCT05699213
- Testing
- Lung MRI, Blood Draw
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center