Clinical trials: sponsored by Cedars-Sinai Medical Center
Antihypertensive Agents, High Blood Pressure
Barber and Pharmacist Coordination to Improve Blood Pressure Management
The original, "Cut Your Pressure Too: The LA Barbershop Blood Pressure Study (LABBPS)" (NCT02321618) was a highly successful cluster-randomized trial of a community centered blood pressure (BP) reduction program focused on…
- Conditions
- Antihypertensive Agents, High Blood Pressure, Hypertension
- Trial name
- NCT07858695
- Testing
- Telemedicine Barbershop BP Reduction
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Cedars-Sinai Medical Center
Actinic Keratoses
5-Fluorouracil and Calcipotriene for Field Treatment of Actinic Keratoses
Combination field therapy with 5-fluorouracil and calcipotriene (5FU/C) has become standard of care among dermatologists for the field treatment of diffuse actinic keratoses (AKs).
- Trial name
- 5FU/C for AKs (NCT07794059)
- Testing
- Combination field therapy with 5-fluorouracil and calcipotriene (5FU/C)
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain, Shoulder Pain
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Postoperative shoulder pain is often reported to be particularly bothersome after laparoscopy. The benefits of local anesthetic, such as bupivacaine, applied to subcutaneous tissue for general postoperative pain management after…
- Trial name
- NCT07400146
- Testing
- Instillation of Bupivacaine with epinephrine over the diaphragm
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Colorectal Cancer, Liver Metastases
SAMe in Prevention of Oxaliplatin-associated Liver Injury
This is an open-label, phase II study that may provide evidence that taking S-adenosylmethionine (SAMe) supplementation prevents oxaliplatin, a type of chemotherapy drug, associated liver toxicity in patients with resectable…
- Conditions
- Colorectal Cancer, Liver Metastases, Liver Metastasis Colon Cancer, Liver Injury
- Trial name
- NCT06258525
- Testing
- Standard of care oxaliplatin-based chemotherapy, S-adenosylmethionine (SAMe) supplement, Surgery
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Overweight and Obesity
CHOICE to AVOID or RESIST
This trials will formally test whether participants' active choice of self-regulatory strategies (AVOID or RESIST) leads to greater adherence to weight management strategies by comparing the CHOICE arms to the randomized arms of…
- Trial name
- NCT06521021
- Testing
- AVOID, RESIST
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Epilepsy Intractable
Neuronal Mechanisms of Human Episodic Memory
The purpose the research is to better understand how the human brain accomplishes the basic cognitive tasks of learning new information, recalling stored information, and making decisions or choices about presented information.
- Trial name
- NCT04500119
- Testing
- Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cedars-Sinai Medical Center
Cerebral Blood Flow, APOE 4
A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)
The study aims to evaluate the safety, feasibility, and preliminary efficacy of the fasting-mimicking diet (FMD) or low-dose daily rapamycin treatment relative to a matched placebo control group when administered over 8 weeks in…
- Trial name
- NCT06682767
- Testing
- FMD1 (LNT22-017-1), Rapamycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Epilepsy Intractable
Neural Mechanisms of Social Attribution From Faces
The purpose of this study is to examine how the brain processes faces, which are some of the most important stimuli that we view, process, and make decisions about as we go through daily life.
- Trial name
- NCT07822178
- Testing
- Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Epilepsy Intractable
Neuronal Mechanisms of Learning and Utilizing Abstract Representations
The purpose of this study is to examine how memories of past experiences are used to guide behavior in novel situations through the cognitive process of abstraction.
- Trial name
- NCT07454785
- Testing
- Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system; Blackrock Cerestim stimulator
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Cedars-Sinai Medical Center
Ligament Injury
Do Oral Contraceptives Protect Against ACL Injuries in Female Athletes
The purpose of this research study is to examine the impact of one type of commonly used birth control pill on blood levels of relaxin and measure changes in knee movement to determine whether there are changes in joint…
- Trial name
- OC (NCT04899778)
- Testing
- Oral Contraceptive Pill, norethindrn a-e estradiol-iron
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Thyroid Cancer
Pre-Clinic Visit Online Education for Thyroid Cancer
Through a pilot randomized controlled trial (RCT), we aim to test the feasibility and preliminary impact of two online educational resources among adult patients with thyroid cancer.
- Trial name
- NCT07690839
- Testing
- THRIVE, ACS "After a Thyroid Cancer Diagnosis" Flyer
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity (BMI>30), Heart Failure With Preserved Ejection Fraction (HFPEF)
Pilot Study of Endoscopic Sleeve Gastroplasty for Obese Patients With Heart Failure and Preserved Ejection Fraction
This is a small research study to see whether losing weight with a minimally invasive weight-loss procedure called endoscopic sleeve gastroplasty (ESG) can help improve symptoms of a type of heart failure called HFpEF in adults…
- Trial name
- NCT07798219
- Testing
- Endoscopic sleeve gastroplasty (ESG)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Cardiovascular Disease
Women's Ischemia Syndrome Evaluation (WISE) Coronary Vascular Dysfunction
This research study is designed to investigate the approaches to noninvasive detection and assessment of coronary vascular dysfunction in women by comparing the testing results from the invasive standard care diagnostic procedure…
- Trial name
- NCT00832702
- Testing
- Cardiac MRI
- Where
- 2 sites in United States
- Volunteers
- 433 people
- Sponsor
- Cedars-Sinai Medical Center
Coronary Microvascular Dysfunction, Heart Failure With Preserved Ejection Fraction (HFpEF)
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
The purpose of this study is to examine small vessel disease (a condition in which the small arteries in the heart become narrowed).
- Trial name
- NCT03876223
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Cedars-Sinai Medical Center
Coronary Atherosclerosis
Coronary Atherosclerosis T1-Weighted Characterization (CATCH)
This study proposes to develop an MRI technique named Coronary Atherosclerosis T1-weighed Characterization (CATCH) that will improve the quality and reliability of coronary atherosclerosis evaluation, as well as simplify the…
- Trial name
- CATCH (NCT03504956)
- Testing
- Cardiac MRI, Contrast, Beta blocker
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Microvascular Coronary Dysfunction, Cardiovascular Disease
WISE CVD - Continuation (WISE HFpEF)
The Women's Ischemia Study Evaluation (WISE), a cohort study of over 1000 women, has made many contributions to the understanding of cardiovascular disease.
- Trial name
- NCT02582021
- Testing
- Coronary Angiography, Coronary Reactivity Testing, Cardiac Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Cedars-Sinai Medical Center
Pancreas Cancer
A Supervised Prehabilitation Program for Patients With Pancreatic Cancer
The purpose of this study is to assess the use of an exercise program in people with pancreatic cancer.
- Trial name
- PREHAB (NCT05692323)
- Testing
- PREHAB
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Cedars-Sinai Medical Center
Takotsubo Cardiomyopathy
The Cedars-Sinai Smidt Heart Institute Takotsubo Registry & Proteomic Study
The Cedars-Sinai SHI Takotsubo Registry and Proteomic Study is an observational registry that will collect retrospective and prospective demographic, clinical, hemodynamic, laboratory and other diagnostic parameters, therapy and…
- Trial name
- NCT03910569
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Cedars-Sinai Medical Center
Pain, Anxiety
Active vs. Passive VR During Office-based ENT Procedures
The purpose of this research is to evaluate whether active virtual reality reduces pain and anxiety more effectively than passive virtual reality during office-based ENT procedures.
- Conditions
- Pain, Anxiety, Chronic Rhinosinusitis (CRS), Nasal Obstruction
- Trial name
- NCT07599826
- Testing
- Passive virtual reality headset or goggles, Active virtual reality headset or goggles
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Cedars-Sinai Medical Center
Overweight and Obesity
Inhibitory Control Adult Weight Management
The purpose of this pilot study is to explore the benefits of supplementing the WW (formerly Weight Watchers) online program with a cognitive training game (PolyRules!) among adults with overweight or obesity.
- Trial name
- NCT04747886
- Testing
- WW Only, WW + PolyRules!
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center