Clinical trials: sponsored by Centre Hospitalier St Anne
Healthy Subjects
Cognitive Biases Under Ketamine
Characterise cognitive biases resulting from low dose ketamine infusion, used as a pharmacological model of psychosis. Our assumption is that low dose ketamine results in reasoning biases by impairing the way uncertainty is…
- Trial name
- KETABI (NCT02235012)
- Testing
- Ketamine
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke, Upper Extremity Paresis
Post-stroke Haptic Feedback Use Deficit: A Comparative and Reliability Study
The aim of this comparative and reliability study is to highlight a deficit in the use of vibrotactile sensory feedback (haptic effect) in the planning and execution of fine manual dexterity movements after stroke.
- Conditions
- Stroke, Upper Extremity Paresis, Manual Dexterity, Sensory Integration Dysfunction
- Trial name
- HapticS (NCT06344221)
- Testing
- Dextrain Manipulandum and haptic feedback device
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke
Simultaneous Recording of Cognitive and Motor Functions After Stroke
Aim: To assess whether a cognitively demanding dual-task has greater impact on manual dexterity in chronic stroke patients than in healthy subjects.
- Trial name
- SACSO (NCT05454748)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Stroke, Acute
Acute Stroke: Prehospital Versus In-HospitAL Initiation of Recanalization Therapy- ASPHALT
ASPHALT is an academic-driven open-label randomized controlled trial of Mobile Stroke Unit (MSU) deployment versus standard care in France, with blinded assessment of efficacy endpoints.
- Trial name
- ASPHALT (NCT05649670)
- Testing
- Mobile Stroke Unit deployment
- Where
- 11 sites in France
- Volunteers
- 450 people
- Sponsor
- Centre Hospitalier St Anne
Catatonia
Catatonia: Effectiveness of Transcranial Direct Current Electrostimulation (CATATOES)
Nearly 10% of people hospitalized in psychiatry have a catatonic syndrome. The treatment of this syndrome is based on lorazepam and electro-convulsive therapy (ECT) in drug-resistant forms.
- Trial name
- CATATOES (NCT06139432)
- Testing
- Active tDCS
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier St Anne
Craving
PHOENIX: Craving Management Smartphone Application
The objective of this study is to evaluate the effectiveness of the addition of nursing follow-up and the PHOENIX application, a personalized and self-adaptive Smartphone application, on the management of craving in patients with…
- Trial name
- PHOENIX (NCT06140472)
- Testing
- Phoenix, Journal de bord
- Where
- 2 sites in France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier St Anne
Mood Disorders, Depression
Use of tDCS Applied to the Orbitofrontal Cortex to Improve Risky Decision-making in a Clinical Population
Decision-making is a complex cognitive function that has been the subject of extensive scientific research in the fields of cognitive and computational neuroscience.
- Conditions
- Mood Disorders, Depression, Suicide
- Trial name
- tDCSDeMOStim (NCT06110559)
- Testing
- Active transcranial direct current stimulation (tDCS)
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier St Anne
Depersonalization Disorder
Depersonalization Disorder: Therapeutic Effect of Neuronavigated Repetitive Transcranial Stimulation
The purpose of this study is to assess the therapeutic efficacy of transcranial magnetic stimulation in patients with depersonalization disorder.
- Trial name
- PERSONA (NCT02476435)
- Testing
- Active rTMS
- Where
- 2 sites in France
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Respiratory Symptoms, Autonomic Nervous System Dysfunction
CoVID-19 Evaluation of Neurological and Autonomic Nervous System Troubles in Intensive Care Unit Patients
Since the spread of the COVID-19 disease, several studies have reported the presence of neurological symptoms in patients infected with SARS-CoV-2 such as dysgeusia, hypo or anosmia, hypopsia, the presence of headaches or…
- Trial name
- COVENANT-ICU (NCT06060795)
- Testing
- Electro-conductance measurement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier St Anne
Psychotic Disorders, Autism Spectrum Disorder
EEG Microstates Across At-Risk Mental States
The goal of this observational study is to compare subjects with at-risk-mental-state, early psychosis, schizophrenia, depression, and autism spectrum disorders, with healthy controls (N = 21 x 6).
- Conditions
- Psychotic Disorders, Autism Spectrum Disorder, Major Depressive Disorder, Schizophrenia
- Trial name
- DEMETER (NCT06045897)
- Testing
- EEG 64 channels, Polysomnography 19 electrodes, Light hypnosis
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia; Psychosis
The IM-ZBULLE Study : " Z-track " and " Airlock " Techniques During Intramuscular Injection of Haloperidol Decanoate
Intramuscular injection (IMI) is the process of administering a drug treatment into muscle tissue. The transmission of skills in this care practice is essentially based on the experience of peers.
- Trial name
- IM-ZBULLE (NCT05995457)
- Testing
- Intramuscular injection of Haloperidol decanoate using the "Z-track" and "Airlock" techniques, Intramuscular injection of Haloperidol decanoate using standard techniques
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier St Anne
Mental Health Issue, Mental Disorder
Being Young : My Mental Health
The goal of this prospective cohort study is to study the evolution of adolescent and young people's mental health over a 12-month period after presentation to an emergency department or crisis service for an acute psychiatric…
- Trial name
- JEMMA (NCT05886595)
- Where
- 7 sites in France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder
Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills
The investigators currently provide the NEAR method (neuropsychological educational approach to cognitive remediation) for people with neurocognitive difficulties, without distinguishing between ASD and schizophrenia.
- Trial name
- NEAR-TSA (NCT05786898)
- Testing
- NEAR-TSA
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier St Anne
Cannabis Use Disorder
Assessment of the Effectiveness of an Integrative Therapy for Cannabis Misuse in Adolescents
The primary objective of this study is to evaluate an Integrative Therapy for Adolescent Cannabis Use (TIMCA), integrating elements of Motivational Interviewing (MI), Cognitive Behavioral Therapies (CBT) and an Attachment-Based…
- Trial name
- TIMCA (NCT05765409)
- Testing
- TIMCA, Treatment as Usual
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier St Anne
Schizophrenia
Planning Your Everyday Life in Virtual Reality : a Study in Schizophrenia;
Patients with schizophrenia , who visit frenquently day-care or day-care activities clinics, often experience difficulties of daily living and cognitive deficits. Living independently is a key for recovery.
- Trial name
- PlaniRev (NCT04011774)
- Testing
- PLANI-REV, RELAXATION
- Where
- 4 sites in France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier St Anne
COVID-19
Plasma Exchange in Covid-19 Patients With Anti-interferon Autoantibodies
COVID-19 associated mortality remains high despite the advances in therapeutics such as dexamethasone. The severity of COVID-19 results from direct viral cytotoxicity, and the inflammatory response, which is associated with a…
- Trial name
- EPIC (NCT05182515)
- Testing
- Therapeutic plasma exchange
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier St Anne
Acute Respiratory Distress Syndrome, COVID-19
Polyvalent Immunoglobulin in COVID-19 Related ARds
As of 30/03/2020, 715600 people have been infected with COVID-19 worldwide and 35500 people died, essentially due to respiratory distress syndrome (ARDS) complicated in 25% of the with acute renal failure.
- Trial name
- ICAR (NCT04350580)
- Testing
- Human immunoglobulin
- Where
- 42 sites in France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier St Anne
Intractable Epilepsy
EXPRESON-IN : Intracerebral Recordings of P3a Responses to Expressive Own-names
Neurophysiologic evaluation of disorders of consciousness (DOC) patients in intensive care unit include late auditory evoked potentials.
- Trial name
- EXPRESON-IN (NCT04810832)
- Testing
- Evoked related potentials
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier St Anne
Sexual Addiction, Hypersexualism
tDCS in Treatment of Craving in Sexual Addiction
In patients with addiction to a substance, an increase in activity in the prefrontal cortex induced by transcranial Direct Current Stimulation -tDCS (non-invasive technique, modulating cortical activity by applying low-intensity…
- Trial name
- CAS (NCT04923451)
- Testing
- Active Trans-cranial direct current stimulation (tDCS)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Post-stroke Depression
ATtention Test and Executive Functions After STroke to Predict Depression.
The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.
- Trial name
- ATTEST-Depress (NCT04008719)
- Testing
- Thymic history, Evaluation of the psychiatric disorders, Cognitive evaluation
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier St Anne