Clinical trials: sponsored by Centre Hospitalier Universitaire, Amiens
Psoriatic Arthritis, HLA b Leader
HLA B Leader in Patients With Psoriatic Arthritis
Psoriatic arthritis (PsA), a chronic immune-mediated heterogeneous inflammatory disease characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis and dactylitis), usually occurs in patients with psoriasis.
- Conditions
- Psoriatic Arthritis, HLA b Leader, HLA B27
- Trial name
- HLABLRP (NCT07718815)
- Testing
- blood test
- Where
- France
- Volunteers
- 658 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chronic Postsurgical Pain, Chronic Opioid Users
Prevention of Chronic Postsurgical Pain in Chronic Opioid Users:
Chronic opioid users undergoing surgery are at increased risk of CPSP, contributing to long-term disability, decreased quality of life, and prolonged opioid exposure.
- Conditions
- Chronic Postsurgical Pain, Chronic Opioid Users, Transitional Pain Service, Postoperative Pain
- Trial name
- PRE-OPIOID (NCT07717151)
- Testing
- standard institutional perioperative management, specialized teleconsultation
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
ERCP, Biomechanic
Evaluation of Biomechanical Forced During the Practice of Endoscopic Retrograde Cholangiopancreatography
A number of best practice recommendations have been developed to improve practitioner comfort, similar to those recommended for digestive surgeons.
- Conditions
- ERCP, Biomechanic, Musculoskeletal Disorders
- Trial name
- RADIO-ERGO (NCT07691580)
- Testing
- CAPTIV system
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Acute Respiratory Distress Syndrome, Ventilator-Induced Lung Injury
Height Measurement Procedures Influence the Risk of Ventilator-induced Lung Injury in ARDS
Acute respiratory distress syndrome is characterized by heterogeneous lung injury, with dependent regions often collapsed and non-dependent regions relatively well-aerated, forming the so called "baby lung." Mechanical…
- Conditions
- Acute Respiratory Distress Syndrome, Ventilator-Induced Lung Injury, Tidal Volume, Predicted Body Weight
- Trial name
- SIZE-ARDS (NCT07595926)
- Testing
- height measured
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Therapy, Pleural Infections
Comparison of Early Pleural Irrigation Strategy With Saline to the Standard of Care for the Management of Complicated Pleural Infections.
Intrapleural enzyme therapy (IET) is regarded by recent guidelines as a "rescue" therapy for managing complicated pleural infections; however, it is associated with significant side effects, including pleural bleeding, pain, and…
- Trial name
- EPISSOC (NCT07666464)
- Testing
- intrapleural irrigation, Standard care
- Where
- France
- Volunteers
- 244 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Subacute Stroke
The Multitasking Rehabilitation She Enhanced Walking Speed Compared to the Simple Post Stroke Rehabilitation Task (AVC)?
Stroke is the leading cause of severe disability in adults. The first cause of alterations in the quality of life and autonomy in these patients are disorders of walking and the balance.
- Trial name
- SYNCOMOT (NCT03009773)
- Testing
- rehabilitation multitasking walking., Traditional walking rehabilitation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
POAG, MIGS
Efficacy and Safety of iStent Inject and Inject W in the Management of Primary Open-angle Glaucoma
Primary open-angle glaucoma (POAG) is a chronic eye disease in which the only validated treatment is to lower intraocular pressure (IOP). It is the 2nd leading cause of blindness worldwide.
- Trial name
- EII (NCT05062668)
- Testing
- cataract operation and istent, cataract operation only
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Septic Shock
TIMP2*IGFBP7 and Transient AKI
Patients with septic shock in the intensive care unit have a high risk to develop acute kidney injury (AKI) and AKI is an independent risk factor of mortality.
- Trial name
- BIOCHECK (NCT03472079)
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Liver Fibroses, Liver Cirrhoses
Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck
Tobacco and alcohol are the two major risk factors for upper respiratory tract cancer (VADS).
- Conditions
- Liver Fibroses, Liver Cirrhoses, Squamous Cell Carcinoma of the Head and Neck
- Trial name
- fibr'HOM (NCT03139058)
- Testing
- Evaluation of the hepatic fibrosis
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Morality
Valvular Aortic Stenosis Prognosis Study
Aortic stenosis is the most common valvulopathy in Western countries. Cardiac EchoDoppler is the reference method for assessment of aortic stenosis and provides prognostic elements.
- Trial name
- EPRAoV (NCT03628313)
- Testing
- Transthoracic ultrasound
- Where
- France
- Volunteers
- 3,450 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thoracic Surgery, Anesthesiology
DEXAMETHASONE for Non-urgent Thoracic Surgery
Thoracic surgery is at high risk of respiratory complications. Despite the improvement of surgical procedures such as video-thoracoscopy, respiratory complications appear in 15 to -20% of procedures.
- Conditions
- Thoracic Surgery, Anesthesiology, Corticosteroids, Respiratory Complication
- Trial name
- SURTHODEX (NCT05136781)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Respiration, Artificial
Weaning From Mechanical Ventilation Comparison of Open-loop Decision Support System and Routine Care
The purpose of this study is to compare mechanical ventilation following advice from the Beacon Caresystem to that of routine care in patients from the state of requiring invasive mechanical ventilation until successful…
- Trial name
- BEACON (NCT02842944)
- Testing
- open loop weaning group (Beacon), Routine care
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Treatment of Suicidal Recidivism in Adolescents Population
The Cognitive-behavioral Approach, Standard Plan Security on Relapse Suicidal Adolescents
The recommendation for the treatment of suicidal adolescents, Cognitive Behavioral Therapy (CBT) targeted new generation offer effective approaches to suicidal crisis and relapse prevention
- Trial name
- SECURIPLAN (NCT02963870)
- Testing
- Security Plan
- Where
- 3 sites in France
- Volunteers
- 109 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Perinatal Mortality, Premature Rupture of Fetal Membranes
Predictive Score for Neonatal Mortality for Women With Premature Rupture of Membranes Between 22 and 28 Weeks of Gestation
Pretern premature rupture of the membranes (PPROM) remains the leading cause of preterm deliveries and neonatal mortality and morbidity. PPROM is defined as rupture of the fetal membranes prior to 37 weeks' gestation.
- Trial name
- PPROM (NCT03108404)
- Testing
- Validation of a diagnostic test
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Alcohol Dependence, Dependence
Screening for Alcohol-related Cognitive Impairments in Cirrhotic Patients
80% of patients with alcohol use disorders (AUD) present cognitive impairments, such as memory and executive functions. These disorders may have repercussions in addiction treatment by altering the patient's adherence to care.
- Conditions
- Alcohol Dependence, Dependence, Cognitive Impairments, Cirrhosis
- Trial name
- CirCo (NCT04490330)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Vasoplegia Syndrome
Dynamic Arterial Elastance Measured by Uncalibrated Pulse Contour Analysis Predicts Arterial Pressure Response to a Decrease in Norepinephrine
Dynamic arterial elastance (Eadyn) has been proposed as an indicator of arterial tone that can predict norepinephrine-dependent arterial pressure.
- Trial name
- VESA (NCT03455738)
- Testing
- vasoplegic syndrome
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Magnetic Resonance Imaging, Tetralogy of Fallot
4D Velocity Mapping of the Heart in rTOF Patients
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
- Trial name
- CARDIOFLUX (NCT02980614)
- Testing
- 4D flow imaging
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hemostasis, Extracorporeal Circulation
Interchangeability of Arterial Coagulation and Venous Coagulation, in the Context of Cardiac Surgeries Under Cardiopulmonary Bypass, Using the DMDiv Hemochron Signature Elite
Adequate coagulation measured using activated clotting (ACT) is important during vascular and cardiac surgeries. Unfractionated heparin is the most common anticoagulant used.
- Conditions
- Hemostasis, Extracorporeal Circulation, Heparin, Cardio-pulmonary Bypass
- Trial name
- COAGAV (NCT05875272)
- Testing
- interchangeability of arterial or venous hemostasis
- Where
- France
- Volunteers
- 201 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cardiorenal Syndrome
Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery
Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow.
- Trial name
- DECONGEST (NCT03684876)
- Testing
- diuretic use
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Disruptive Mood Dysregulation Disorder, Prognosis Factors
Evolution of DMDD Children and Adolescent
Little is known about the natural course and prognosis factors of inpatients and outpatients with Disruptive Mood Dysregulation Disorder (DMDD).
- Conditions
- Disruptive Mood Dysregulation Disorder, Prognosis Factors, Suicidal Behaviors, Actigraphy
- Trial name
- ACTIHUMEURp3 (NCT04820946)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens