Clinical trials: sponsored by Centre Hospitalier Universitaire Dijon
Severe Sepsis, Persistent Hypotension
Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of France
The epidemiology of this study aims and outcome of patients with septic shock in the intensive care unit (or versatile) of the North-East region in france as well as the modalities of care.
- Trial name
- NCT01903746
- Volunteers
- 1,495 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Patients With Spontaneous Rupture of the Fetal Membranes
Kinetics of Inflammation Markers in Maternal Plasma: Study of the Correlation With the Diagnosis of Chorioamnionitis in Women Hospitalized for Spontaneous Rupture of the Fetal Membranes
The principal aim of this study is to help obstetricians to diagnose chorioamniotic infection early, in cases of premature rupture of the fetal membranes before 34 WA, by proposing earlier and more specific markers of infection…
- Trial name
- NCT01903759
- Testing
- Blood samples
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Inflammatory Disease
Study of the Proteome and Cytokines During Inflammatory Syndromes of Different Etiologies.
The hypotheses of our research are based on the fact that various pathological states, infection, cancer, inflammatory disease, can induce an inflammatory syndrome, through different pathways, even though the clinical…
- Trial name
- Proteome (NCT01903642)
- Testing
- proteomic analysis
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes
TReatment by Insulin Continuous Infusion in Type 2 DIAbetes
The aim of the TRICIDIA2 study is to compare two modalities of administration of insulin. In our future study, the investigators wish to study if the treatment by continuous infusion of insulin improves the insulinosensitivity of…
- Trial name
- TRICIDIA2 (NCT01889914)
- Testing
- 2 different procedures of administration of insulin
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Knee Osteoarthritis
Evaluation of a Distraction-rotation Knee Unloader Brace in Patients With Medial Knee Osteoarthritis.
The aim of this study is to confirm the biomechanical effects and evaluate functional benefits of a new knee brace combining valgus inducing effect on medial compartment and leg external rotation during the stance phase in…
- Trial name
- ORFEVRE (NCT01884883)
- Testing
- PROTEOR Internal unicompartmental knee brace
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Solid Tumors
Effects of OM-174 in Adult Patients With Solid Tumors
Methods Patients received OM-174 twice weekly for a total of 5, 10 or 15 injections of either 600, 800 or 1000 µg/m². Pharmacokinetic analysis and cytokine dosages were performed.
- Trial name
- OM-174 (NCT01800812)
- Testing
- Injections of OM-174
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Carcinoma, Hepatocellular
Chemoembolisation of Non Resectable, Non Metastatic Hepatocellular Carcinomas
The purpose of this study is to determine the maximal tolerated dose of idarubicin for chemoembolization of non resectable non metastatic hepatocellular carcinoma.
- Trial name
- NCT01040559
- Testing
- idarubicin
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Hole
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Macular Hole
To evaluate the correlations between anatomical and functional changes studied with microperimetry (MPM) and spectral-domain OCT (SD-OCT) in patients after successful repair of idiopathic macular hole (MH).
- Trial name
- NCT01757600
- Testing
- Microperimetry
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Type 2 Diabetes Mellitus, Overweight
Impact of Liraglutide on Sensory Perception, Sensory Specific Satiety, Liking and Wanting in Type 2 Diabetic Patients
Besides their potential action in the treatment of type 2 diabetes mellitus (T2DM), GLP-1 analogues decrease satiety and food intake leading to a significant weight loss in patients.
- Trial name
- NCT01599338
- Testing
- Liraglutide
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Epiretinal Membrane
Microperimetry and Optical Coherence Tomography (OCT) in Idiopathic Epiretinal Membrane
Purpose: To evaluate macular sensitivity and its correlation with visual acuity and Spectral Domain Optical Coherence Tomography (SD-OCT) in eyes with idiopathic epiretinal membrane (ERM).
- Trial name
- NCT01481987
- Testing
- Epiretinal Membrane Surgical treatment
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Intraocular Pressure,, Postoperative Complications
Primary Vitrectomy for the Treatment of Retinal Detachment in Highly Myopic
Purpose: To assess the functional and anatomical outcome of primary vitrectomy without scleral buckling for rhegmatogenous retinal detachment (RRD) in highly myopic eyes with axial length over 30 mm.
- Trial name
- NCT01480505
- Testing
- Pars plana vitrectomy with gas tamponade
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Rhegmatogenous Retinal Detachment
Anatomical and Functional Macular Changes in Retinal Detachment
The purpose of this study is to evaluate the correlation between morphologic changes in the outer retina and visual function after successful repair of rhegmatogenous retinal detachment with macula off.
- Trial name
- NCT01343134
- Testing
- Measure the outer retina by spectral domain optical coherence tomography (HRA Spectralis; Heidelberg), and microperimetry (OPKO Instruments)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Glaucoma
Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD
The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.
- Trial name
- NCT00629044
- Testing
- Assessing the blood level of cholesterol 24 S Hydroxylase
- Where
- France
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Macular Hole, Visual Acuity
Combined Versus Successive Macular Hole and Cataract Surgery
The purpose of this study is to compare functional and anatomical results of a combined surgery and two time surgery for macular hole and cataract extraction in one hundred and twenty patients (120 eyes) with idiopathic Macular…
- Trial name
- NCT01069029
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Glaucoma
Lipid Profile of Tenon's Capsule
The purpose of this study is to provide data on the lipid profile of the Tenon's capsule in Human glaucomatous eyes and to establish possible relationships with the short term outcome of filtration surgery.
- Trial name
- NCT01021657
- Testing
- trabeculectomies, non penetrating deep sclerectomies
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Retinal Detachment
Anticoagulant and Antiplatelet Agents in Patients Undergoing Vitreoretinal Surgery
Purpose: To establish the prevalence of anticoagulant, aspirin, and clopidogrel use in patients undergoing vitreoretinal surgery, and to compare the outcome of peribulbar anesthesia between users and non-users.
- Trial name
- NCT01020656
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Epiretinal Macular Membrane, Cataract Extraction
Epiretinal Macular Membrane and Cataract Extraction
The investigators proposed to assess the functional and anatomical outcomes of cataract and idiopathic epiretinal macular membrane extraction in combined and consecutive surgeries.
- Trial name
- NCT00851760
- Testing
- Consecutive surgery, Combined surgery
- Where
- France
- Volunteers
- 174 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Idiopathic Macular Hole
Outcome of Idiopathic Macular Hole
The purpose of this study is to evaluate the role of cataract surgery and cystoid macular edema (CME) on reopening of idiopathic macular holes (IMH).
- Trial name
- NCT00941291
- Where
- France
- Volunteers
- 135 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes
Effects of Rosuvastatin on the, in Vivo, Kinetic of apoB and apoA1, Using Stable Isotopes, in Type 2 Diabetic Patients
Statins have been shown to reduce significantly the risk for cardiovascular events in patients with type 2 diabetes and statin therapy is largely recommended in this high cardiovascular risk population.
- Trial name
- NCT00658463
- Testing
- Rosuvastatin
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Dijon