Clinical trials: sponsored by Chang Gung Memorial Hospital
The Genetic Variation of Type 1 Diabetes
PST Linkage Based Analysis in the Family of More Than Two Members With Type 1 Diabetes in Taiwan
The purpose of this study is to explore the susceptible genes for Type 1 diabetes in Taiwan through the new genetic study methods.
- Trial name
- PATT (NCT01955746)
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Chang Gung Memorial Hospital
Diabetes Mellitus
Evaluation of Group Health Teaching With Video in Diabetic Patients
Objective:Health videos and group education to allow patients to a correct understanding of diabetes and insulin treatment. Method: Standards and number of patients: The patients received subcutaneous insulin injection, estimated…
- Trial name
- EGVD (NCT01917227)
- Testing
- Video
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Dehydration
Neuroprotective Therapy and Therapeutic Target in Emergency Department
The investigators studied laboratory measurements and previously identified risk factors to identify factors predictors of early deterioration following stroke.
- Trial name
- NCT02143596
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- Chang Gung Memorial Hospital
Osteoarthritis, Knee
Management of Postoperative Pain Following Total Knee Arthroplasty by Using Acupuncture-moxibustion Therapy
Orthopedic surgery is reportedly among the most painful surgical procedures. Surgical damage following major orthopedic surgery often involves a large, deep incision with considerable tissue dissection and muscle, bone, and…
- Trial name
- NCT01047384
- Testing
- acupuncture-moxibustion therapy, Regular therapy
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Swelling
Effect of Steroid for the Postoperative Swelling After Orthognathic Surgery
Postoperative swelling is one of most common concerns to plastic and oromaxillary surgeons after orthognathic surgery. The purpose of this study is to develop a steroid regimen protocol for minimizing postoperative facial…
- Trial name
- NCT01431014
- Testing
- Dexamethasone"low-dose", Dexamethasone"high-dose"
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Psoriasis Vulgaris
Mechanistic Study of Indigo Naturalis in Treating Psoriasis
The potential effect of indigo naturalis on the immune system is unknown. The investigators hypothesize that the therapeutic effect of indigo naturalis in psoriasis may involve inhibiting the activation of Th1 and Th17 cells that…
- Trial name
- NCT02088281
- Testing
- Indigo naturalis extract in oil ointment
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson's Disease
The Differential Diagnosis of Parkinson's Disease and Parkinsonism by Positron-emission Tomography
The objective of this protocol is to analyze the sensitivity and specificity of 18F-DTBZ PET to the differential diagnosis of Parkinson's disease (PD) and other parkinsonism disorders, including multiple system atrophy (MSA)…
- Trial name
- NCT01824056
- Testing
- 18F-FDG
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Dementia
Music Therapy to Promote Emotion and Cognition for Dementia
The purpose of this study is to determine if the effects of music therapy alter emotion and cognition performances of individuals with mild to moderate dementia.
- Trial name
- NCT01958983
- Testing
- Music Therapy Group Session
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Transformation of Somatosensory and Visual Coordinate Systems
Manipulation of object is a multisensory experience that includes tactile motion between the object and the fingerpad, visual motion elicited by the motion the object and the movement of the hand, and the active motor commend to…
- Trial name
- NCT01177462
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acute Respiratory Distress Syndrome, Acute Lung Injury
Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS)
The purpose of this study is to investigate the change of extravascular lung water (EVLW), cytokine and oxygenation parameters in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) after alveolar…
- Trial name
- NCT01552070
- Testing
- Recruitment maneuver, without recruit maneuver
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
BDNF, DNA Methylation, Suicide, Drug Responses.
Epigenetic Regulation of BDNF in Schizophrenia
In this proposal, we will (1) detect the associations between BDNF and Trk B gene DNA methylation, histone modification, psychotic symptoms, obesity, suicide and antipsychotic drug responses in Taiwanese patients (2) discuss the…
- Trial name
- NCT01021449
- Where
- Taiwan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Schizophrenia
Mitochondria and Schizophrenia: Effects of Antipsychotic Drugs
The investigators will investigate 1. the relationships between oxidative stress-, apoptosis-related markers, mitochondria DNA copy numbers and the clinical psychopathology of schizophrenia, including severity of positive and…
- Trial name
- NCT01479413
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Chang Gung Memorial Hospital
Hallux Valgus
Effect of Botulinum Toxin to Hallux Valgus in Addition to Total Contact Insole
The investigators propose a new therapeutic approach by injecting Botulinum Toxin Type A (BTA) to the oblique and transverse heads of adductor muscle of the great toe.
- Trial name
- NCT01501500
- Testing
- BOTOX, Normal Saline (0.9% NaCl)
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Autism
rTMS for Adults With Autistic Spectrum Disorder
rTMS over dorsolateral prefrontal cortex is effective in reducing repetitive behaviors in adults with autistic spectrum disorder rTMS over posterior superior temporal sulcus is effective in improving social ability in adults with…
- Trial name
- NCT01918787
- Testing
- repetitive TMS
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Disease, AST-120
Effect of An Oral Absorbent AST-120 in Late-stage Chronic Kidney Disease (CKD) Patients.
Recent research work has directed especial attention toward a distinct group of uremic retension molecules, called "protein-bound uremic toxins". The prototypes of this group of uremic toxins are indoxyl sulfate and p-cresol.
- Trial name
- NCT01681303
- Testing
- AST-120
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Chang Gung Memorial Hospital
Type 2 Diabetes Mellitus
Additional GLP-1 Analogue on CSII Treatment for Poorly Controlled Type 2 Diabetic Patients
Background: Continuous subcutaneous insulin infusion (CSII) has been demonstrated to be an effective clinical tool for intensive insulin therapy in Type 1 diabetic patients.
- Trial name
- AGAC2 (NCT01473147)
- Testing
- Exenatide, Normal saline
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Chang Gung Memorial Hospital
Surgical Procedure, Unspecified
Functional Nasal Surgery at the Time of Le Fort I Osteotomy: A Prospective, Single-blind, Randomized Trial
Objectives: The aims of this study are (1) to define the effectiveness of functional nasal surgery during Le Fort I osteotomy on nasal obstruction through objective as well as subjective evaluations, (2) to determine guideline…
- Trial name
- NCT01883687
- Testing
- Septoplasty
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Unilateral Complete Cleft Lip
Comparison of Two Nasoalveolar Molding Techniques in Complete Unilateral Cleft Lip Patient
Two types of Presurgical Nasoalveolar Molding (NAM) coexist in Craniofacial Center in Chang Gung Memorial Hospital. The objective of this study is to compare the number of clinical visits, total prices, complications and nasal…
- Trial name
- NAM (NCT01883726)
- Testing
- Grayson's presurgical nasoalveolar molding, Figueroa's presurgical nasoalveolar molding
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy
The Relationship of Bone Strength and Fitness Training in Children With Cerebral Palsy
In the first year, all subjects received clinical assessments include subjective assessment, basic data, nutritional status and fitness assessments.
- Trial name
- NCT01378442
- Testing
- fitness training program
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Third Division of Fifth Cranial Nerve Disorder
IAN Injury After BSSO in Oral Clefts
Background and Purposes: Orthognathic surgery is necessary in more than 25% of patients with cleft lip and palate (CLP) to correct skeletal discrepancy and to obtain harmonious facial esthetics in the final phase treatment.
- Trial name
- NCT01875965
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital