Clinical trials: sponsored by Chinese PLA General Hospital
Postoperative Delirium
Relationship Between Perioperative Sleep Disturbance and Postoperative Delirium
The investigators are performing this research study to understand the role of sleep disturbance on the incidence of delirium after surgery.
- Trial name
- NCT05457387
- Where
- China
- Volunteers
- 11,927 people
- Sponsor
- Chinese PLA General Hospital
Atrial Fibrillation
Atrial Fibrillation Monitoring on Patients With Lymphoma After Chemotherapy
This prospective cohort study is to investigate the incidence of atrial fibrillation after chemotherapy by aplying wearable ECG recoder and the risk factors on patients with newly diagonsed lymphoma
- Trial name
- NCT05454878
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Delirium in Old Age
Effect of Intraoperative Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Robot-assisted Pancreaticoduodenectomy: a Randomized Controlled Study
To observe the effect of intraoperative dexmedetomidine on the incidence of postoperative delirium, postoperative analgesic drug requirements and pain scores in elderly patients undergoing robot-assisted pancreaticoduodenectomy.
- Trial name
- NCT05274789
- Testing
- Dexmedetomidine, Saline
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Potassium, Decreased Level, Postsurgical Pain, Chronic
Serum Potassium as a Predictor of Clinical Outcomes in an Older Patient Cohort With Chronic Postsurgical Pain
Perioperative serum potassium in patients over 65 impacts recovery, quality of life and physical functioning. While perioperative serum potassium is an important preoperative risk factor for poor surgical outcomes in older…
- Trial name
- NCT05385640
- Testing
- NO intervention
- Where
- China
- Volunteers
- 3,088 people
- Sponsor
- Chinese PLA General Hospital
Chronic Postsurgical Pain
Clinical Prediction Model and External Validation of Chronic Postsurgical Pain in Elders
This study will collect perioperative pain-related data of elderly patients in multi-centers. Analyzing these collected data to find the high-risk factors of chronic postsurgical pain in elderly patients and to establish an…
- Trial name
- NCT05372406
- Testing
- • no intervention
- Where
- China
- Volunteers
- 7,770 people
- Sponsor
- Chinese PLA General Hospital
aGVHD
Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
The purpose of this study is to determine the efficacy and safety of combined ATG （antithymocyte globulin ） regimen for aGVHD(acute graft-versus-host disease ) prophylaxis in matched sibling donor peripheral blood stem cell…
- Trial name
- NCT02677181
- Testing
- ATG, CsA, mycophenolate mofetil
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Pneumonia
M-ROSE Combined With mNGS in Severe Hospital-acquired Pneumonia
The purpose of this study is to determine the value of M-ROSE（microbiological rapid on-site evaluation）in severe hospital-acquired pneumonia.
- Trial name
- NCT05300776
- Testing
- M-ROSE analysis
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Chinese PLA General Hospital
MRI, Osteoarthrosis
Osteoarthrosis on 7.0T Magnetic Resonance Imaging
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater…
- Trial name
- NCT05343104
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Pancreatic Cancer, Biliary Tract Cancer
An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTC
Immunotherapy of cancer based on PD-1/PD-L1 blockade has prompted a revolution in cancer clinical management, albeit as yet immunotherapy-based treatment approaches in pancreatic cancer and biliary tract cancer (BTC) remain to…
- Trial name
- NCT05327582
- Testing
- Durvalumab, Lenvatinib, Nab paclitaxel
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Chinese PLA General Hospital
Solid Tumor, Hematological Malignancy
Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells
The aim of this prospective study is to evaluate the feasibility and efficacy of metoprolol, a beta-1 adrenergic receptor blocker, in the treatment of cytokine release syndrome (CRS) caused by chimeric antigen receptor T (CAR T)…
- Trial name
- NCT04082910
- Testing
- Metoprolol, metoprolol, infliximab, etanercept, tocilizumab and/or other agents
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Relapsed/Refractory Non-Hodgkin Lymphoma, Advanced Solid Tumors
Study of Chidamide, Decitabine and Immune Checkpoint Inhibitors in R/R NHL and Advanced Solid Tumors
This phase I/II trial aims to evaluate safety and efficacy of Chidamide, Decitabine and Immune checkpoint inhibitors in relapsed/refractory Non-Hodgkin Lymphoma and advanced solid tumors.
- Trial name
- NCT05320640
- Testing
- Chidamide, Decitabine, Immune checkpoint inhibitors（anti-PD1/PD-L1/CTLA4 antibodies）
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Diabetic Kidney Disease
Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy
With the rapid increase of diabetic nephropathy worldwide, type 2 diabetes mellitus(DM) is the leading cause of end-stage renal disease(ESRD).
- Trial name
- NCT03865914
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Chinese PLA General Hospital
Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia
Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCT
This study investigates the infusion safety and potential curative properties of ex-vivo expanded γδ T cells obtained from the same donor for patients who have hematological malignancies and have accepted allogeneic hematopoietic…
- Conditions
- Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Lymphoma
- Trial name
- NCT04764513
- Testing
- Ex-vivo expanded γδ T cell infusion
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma
The Surveillance of Hepatocellular Carcinoma
Early detection of hepatocellular carcinoma is vita to the prognosis of patient. In this study, the occurrence and development of liver cancer were supervised by imaging examination, and the dysplastic nodules will be…
- Trial name
- NCT05286099
- Testing
- Imaging examination and/or blood test
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Brain Tumor, MRI
Brain Diseases on 7.0T Magnetic Resonance Imaging
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting brain diseases. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater…
- Conditions
- Brain Tumor, MRI, Cerebrovascular Disease
- Trial name
- NCT05287750
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Postoperative Acute Kidney Injury
Predictive Nomogram for Postoperative Acute Kidney Injury (AKI) in Elderly Patients Following Liver Resection
Acute kidney injury (AKI) is a severe complication after liver resection and is associated with morbidity and mortality. The incidence of postoperative AKI is significantly higher in elderly patients, especially in those with…
- Trial name
- NCT04922866
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 843 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Acute Kidney Injury
Intraoperative Renal Desaturation and Postoperative Acute Kidney Injury
The aim of this study is to investigate the changes in renal regional oxygen saturation (rSO2) monitored by near-infrared spectroscopy (NIRS) and its relationship with the occurrence of postoperative AKI.
- Trial name
- NCT04967105
- Testing
- Near-infrared spectroscopy
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Chinese PLA General Hospital
Kidney Failure,Chronic
Safety and Effectiveness Evaluation of Two Kinds of Peritoneal Dialysate
This study is to evaluate the effectiveness and safety of Huaren Peritoneal Dialysate and Baxter Peritoneal Dialysate, investigate the proper dialysis dose for Chinese CAPD patients.
- Trial name
- SEED (NCT01779557)
- Testing
- Huaren Peritoneal Dialysate, Baxter Peritoneal Dialysate
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma, Ablation
Plan for Microwave Thermal Field
Develop an intelligent system based on contrast-enhanced ultrasound and clinical information to help doctors automatically obtain ablation parameters (ablation needle number, ablation needle type, ablation time,ablation power)…
- Trial name
- NCT05270642
- Testing
- Microwave Thermal guided by Plan for Microwave Thermal Field system
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Chinese PLA General Hospital
CD19+ Relapse/Refractory B-ALL
CAR-T-19 Cells for Patients With CD19+ Relapse/Refractory B-ALL
This is a single-arm, open-label phase I study to determine the safety, tolerability, and recommended dose (RD) of CAR-T-19 cells for patients with CD19+ relapse/refractory B-ALL under the age of 25.
- Trial name
- NCT05270772
- Testing
- CAR-T-19 Cells
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Chinese PLA General Hospital