Clinical trials: sponsored by Chinese PLA General Hospital
Endometrial Carcinoma Stage I
A Prospective Multi-center Study on Using Sonazoid Diagnose Early Stage Endometrial Cancer
Sonazoid as a new generation of ultrasound contrast agent.This study based on the features of Sonazoid specific angiography and higher mechanical index, the role of Sonazoid in the early diagnosis of Endometrial carcinoma was…
- Trial name
- NCT04961775
- Testing
- Perflubutane Microspheres for Injection
- Where
- China
- Volunteers
- 277 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Mortality, Anesthesia
The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China
At present, the elderly population in China has reached 241 million, and there are more than 20 million elderly surgical patients every year, accounting for about 25% of the surgical population.
- Conditions
- Postoperative Mortality, Anesthesia, Elderly Patients, Noncardiac Surgery
- Trial name
- NCT04389008
- Testing
- no interventions
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Chinese PLA General Hospital
Adenocarcinoma of Esophagogastric Junction
Transhiatal/Transabdominal Approach Compare With Thoracoabdominal Approach for Siewert II Adenocarcinoma of Esophagogastric Junction
To compare transhiatal / transabdominal approach with thoracoabdominal approach for Siewert II adenocarcinoma of esophagogastric junction
- Trial name
- NCT04910789
- Testing
- transhiatal/transabdominal approach, thoracoabdominal approach
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Chinese PLA General Hospital
Non-hodgkin Lymphoma,B Cell
Azacytidine, Bendamustine, Piamprizumab in Refractory/Relapsed B-cell Non-Hodgkin's Lymphoma
This is an open label, single arm, phase I/II for patients with r/r Non-Hodgkin's Lymphoma . The purpose is to evaluate the safety and efficacy of the combination with Azacytidine, Bendamustine and Piamprizumab
- Trial name
- NCT04897477
- Testing
- Azacytidine, Bendamustine and Piamprizumab
- Where
- 2 sites in China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Solid Tumor, Lymphoma
An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma
Radiotherapy is a regular care for metastatic solid tumors or lymphoma, and it can induce immunogenic death of tumor cells and a stronger immune response.
- Trial name
- NCT04873440
- Testing
- Manganese Chloride, Radiotherapy, Chemo-immunotherapy
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Adults
Safety and Efficacy Evaluation of S (+) - Ketamine in Adults
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in adults in perioperative settings.
- Conditions
- Postoperative Pain, Adults, Anesthesia
- Trial name
- NCT04837170
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma, Thermal Ablation
Thermal Ablation Combined With Anlotinib and TQB2450 Solution for HCC
In this study, investigators aimed to evaluated the efficacy and safety of microwave ablation combined with anlotinib and TQB2450 Solution in patients with advanced hepatocellular carcinoma.
- Conditions
- Hepatocellular Carcinoma, Thermal Ablation, Anlotinib, PDL-1
- Trial name
- NCT04665609
- Testing
- Anlotinib and TQB2450 solution, TQB2450 solution
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Liver Neoplasms
Percutaneous Microwave Ablation Under Ultrasound Guidance for Liver Cancer: a Multicenter Analysis
Ultrasound-guided percutaneous MWA of liver cancer is a relatively new technique with favorable long-term outcomes.Butthe results are mainly from single center reports.A larger scale data need to be analyzed to evaluate the…
- Trial name
- NCT03045952
- Testing
- microwave ablation device
- Where
- China
- Volunteers
- 1,908 people
- Sponsor
- Chinese PLA General Hospital
Benign Thyroid Nodules, Ablation
Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study
Compared with traditional treatment methods, ultrasound-guided thermal ablation is more targeted, less invasive and more reliable.
- Trial name
- NCT04046354
- Testing
- Ultrasound-guided Percutaneous Microwave Ablation, Ultrasound-guided Percutaneous Radiofrequency Ablation
- Where
- China
- Volunteers
- 149 people
- Sponsor
- Chinese PLA General Hospital
Type 2 Diabetes, Mesenchymal Stem Cells
Mesenchymal Stem Cells to Treat Type 2 Diabetes
Umbilical cord mesenchymal stem cells indicate the therapeutic effects and safety on type 2 diabetes by characteristics of secretion and immune Immunomodulation.
- Trial name
- UC-MSCs (NCT02302599)
- Testing
- Umbilical cord mesenchymal stem cells, Controlled suspension liquid
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Chinese PLA General Hospital
Osteoporosis, Osteopenia, Osteoporosis
Intervention Study of Drugs in Patients Osteopenia and Osteoporosis
This is a 12 months, randomized, multicenter, open-label, parallel-group study in postmenopausal women and male aged 50 years or old with osteoporosis or osteopenia in China to evaluate the efficacy and safety of different…
- Trial name
- NCT04719572
- Testing
- Basic treatment group, Basic treatment+ anti-osteoporosis drug group, Basic treatment + non-drug treatment group
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Chinese PLA General Hospital
Optic Neuritis
Epidemiologic and Clinical Characteristics of Optic Neuritis in China
This will be a hospital-based retrospective multi-center study on epidemiologic and clinical characteristics of optic neuritis among Chinese. The investigation will cover about 29 provinces or municipalities all around China.
- Trial name
- NCT04257734
- Testing
- observation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer, Chemotherapy Effect
Oxaliplatin Combined With S-1(SOX) Neoadjuvant Chemotherapy for Different Cycles in Patients With Gastric Cancer
RESONANCE-II trial is a prospective, multicenter, randomized, controlled phase III study which will enroll 524 patients in total. Patients with eligibility will be registered, pre-enrolled and receive three cycles of SOX.
- Trial name
- RESONANCE-II (NCT04483076)
- Testing
- Chemotherapy drug, Gastrectomy, Laparoscopic exploration
- Where
- China
- Volunteers
- 524 people
- Sponsor
- Chinese PLA General Hospital
Liver Cirrhosis, Gastroesophageal Varices
Risk Prediction of Bleeding in Liver Cirrhosis by Combi-elastography
Through the parameters of liver stiffness and spleen stiffness obtained by combi-elastography technique, summarize and analyze the warning index of esophagogastric variceal bleeding in patients with cirrhosis, so as to provide a…
- Conditions
- Liver Cirrhosis, Gastroesophageal Varices, Variceal Hemorrhage
- Trial name
- NCT04640350
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
HCC, Recurrence Tumor
Combi-elastography Assessment of HCC Recurrence After Thermal Ablation Multi-center Study
Combined F index, A index,ATT index and spleen stiffness to predict tumor recurrence in different liver settings after thermal ablation of HCC.
- Trial name
- NCT04640363
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
In-stent Restenosis, Neo-atherosclerosis
Identification of Neoatherosclerosis in ISR Patients Based on Artifical Intelligence
Based on the large population of patients, in-stent restenosis (ISR) is still an important problem in the field of cardiovascular disease.
- Conditions
- In-stent Restenosis, Neo-atherosclerosis, Retrospective
- Trial name
- NCT04220437
- Testing
- no interventin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese PLA General Hospital
Non Alcoholic Fatty Liver, Hepatitis B
Combi-elastography Assessment of Chronic Liver Disease Multi-center Study
HITACH developed a new combi-elastography imaging technology combines shear wave imaging and strain imaging technology. In the study, not only the F index which is related to the stage of liver fibrosis can be obtained, but also…
- Conditions
- Non Alcoholic Fatty Liver, Hepatitis B, Drug-induced Liver Injury
- Trial name
- NCT04625166
- Where
- China
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Pancreatic Cancer
An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer
The outcome of pancreatic cancer is extremely poor. NCCN guidelines recommend FOLFIRINOX or modified-FOLFIRINOX as the first-line chemotherapeutic regimen, but the response rate is unacceptably low.
- Trial name
- NCT03989310
- Testing
- Manganese Chloride, nab-paclitaxel, Gemcitabine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese PLA General Hospital
ICU Acquired Weakness, Rehabilitation
Effects of Respiratory Rehabilitation on ICU Patients
Effects of respiratory rehabilitation on patients after extubation
- Trial name
- NCT04368286
- Testing
- pulmonary rehabilitation
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Coronary Heart Disease, Chronic Coronary Syndrome
Efficacy and Mechanism of TCCRP in Patients With Chronic Coronary Syndrome Under Fusion Cardiac Rehabilitation Model
This study is a prospective, multi-center, randomized controlled clinical study. It developed an innovative Tai Chi Cardiac Rehabilitation Program (TCCRP) for patients with chronic coronary syndrome (CCS) and evaluated the…
- Trial name
- NCT03936504
- Testing
- Control Group ：conventional exercise rehabilitation programs (CERP), Experimental Group ：Tai Chi cardiac rehabilitation program (TCCRP)
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital