Clinical trials: sponsored by Chinese PLA General Hospital
Vitamin D Deficiency
Intervention Study of Vitamin D Supplementation to Prevent Cardiovascular Disease
This is a 9 months, randomized, single center, open-label, parallel-group study to compare the efficacy and safety parameters of vitamin D supplementation in vitamin D deficiency subjects in China.
- Trial name
- NCT03339427
- Testing
- vitamin D, control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Obesity
Effect of Nutrition and Lifestyles on Obesity and Chronic Disease in China
This research is aimed at verifying the effects of diets with high protein and low glycemic index (GI) on weight management among overweight or obese Chinese adult.
- Trial name
- NCT02509741
- Testing
- Education, Food replacement, IOT monitoring
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
STEMI - ST Elevation Myocardial Infarction, Glucagon-like Peptide-1
Plasma Glucagon-like Peptide-1 Levels and In-hospital Complications in ST-segment Elevation Myocardial Infarction
Glucagon-like peptide-1 (GLP-1), produced mainly in enteroendocrine cells, participates in energy homeostasis and glucose metabolism by regulating islet hormone secretion, gastrointestinal motility, and food intake, making GLP-1…
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Glucagon-like Peptide-1, Bleeding, Complications
- Trial name
- NCT03314844
- Volunteers
- 564 people
- Sponsor
- Chinese PLA General Hospital
Biliary Tract Cancer
Study of PD-1 Inhibitor in Combination With Gemcitabine/Cisplatin for Advancer BTCs
This is a single-arm, phase I/II trial in biliary tract cancer (BTC) patients. The purpose of this trial is to evaluate the safety and effect of PD-1 inhibitor in combination with gemcitabine/cisplatin chemotherapy in patients…
- Trial name
- NCT03311789
- Testing
- PD-1 inhibitor + Gemcitabine + Cisplatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
ST-segment Elevation Myocardial Infarction
Association Between Plasma Melatonin and No-reflow
ST-segment elevation myocardial infarction (STEMI) is an acute manifestation of coronary heart disease, remaining a frequent cause of death.
- Trial name
- NCT03306303
- Volunteers
- 1,700 people
- Sponsor
- Chinese PLA General Hospital
Reperfusion Injury, Myocardial
Effects of Melatonin on Reperfusion Injury
Acute myocardial infarction is a major cause of mortality and morbidity. Primary percutaneous coronary intervention (pPCI) is currently the most effective treatment strategy in acute myocardial infarction.
- Trial name
- NCT03303378
- Testing
- melatonin (Helsinn Chemical Co, Biasca, Switzerland)
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Chinese PLA General Hospital
Coronary Angiography, Glucagon-like Peptide-1
Plasma Glucagon-like Peptide-1 Levels and Acute Myocardial Infarction
GLP-1(9-36) amide and (9-37), which was previously thought to be the inactive metabolite of GLP-1, also exerts cardioprotective effects.
- Trial name
- NCT03129594
- Testing
- plasma glucagon-like peptide-1 levels
- Volunteers
- 709 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer
The Study of Conversion Surgery for Apatinib in Combination With SOX for Patients With Unresectable Gastric Cancer
This is a Prospective，Single-center，Single-arm，Open-label exploratory clinical trial evaluating the efficacy and safety of Conversion Surgery for Apatinib plus SOX for patients with unresectable gastric cancer.
- Trial name
- NCT03007446
- Testing
- Apatinib, Oxaliplatin, S-1
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese PLA General Hospital
Breast Tumor, Microwave Ablation
Comparison of Microwave Ablation With Cryoablation for Breast Tumor
The investigators will perform this study to prospectively compare the clinical outcome after percutaneous microwave ablation(MWA) and cryoablation of benign and malignant breast lesion under ultrasound (US) guidance.
- Conditions
- Breast Tumor, Microwave Ablation, Cryoablation
- Trial name
- NCT03286413
- Testing
- microwave ablation
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Chinese PLA General Hospital
Cancer of Pancreas
Phase 2 Trial of Gemcitabine vs S-1 vs Gemcitabine Plus Nab-paclitaxel as Adjuvant Chemotherapy of Post-operative Pancreatic Cancer Patients
Pancreatic cancer is one of the deadliest tumor types, there is no effective treatment method clinically. Recently radical surgical resection is recommended for this cancer, How to improve the survival rate of patients is the…
- Trial name
- NCT03278015
- Testing
- Nab-paclitaxel plus Gemcitabine, Gemcitabine monotherapy, S-1 monotherapy
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Disease
Chinese Observational Prospective Study of Aging Population With Chronic Kidney Disease(C-OPTION)
The study is an observational, multicenter, prospective cohort study aimed at evaluating a 5-year screening programme for chronic kidney disease(CKD) in a population of elderly patients, aged 65 years or more, in China.To analyze…
- Trial name
- NCT03246204
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Disease
Screening and Assessing the Risk Factors and Complications of Chronic Kidney Disease
The study is an observational, cross-sectional study aimed at screening and accessing risk factors and complications for Chinese chronic kidney disease (CKD) patients.
- Trial name
- NCT03246191
- Testing
- blood sample collection
- Volunteers
- 900 people
- Sponsor
- Chinese PLA General Hospital
Rectal Cancer
A Pilot Study of Neoadjuvant Chemotherapy Combined With Bevacizumab for Locally Advanced Rectal Cancer
Background: Neoadjuvant chemoradiotherapy (CRT) and total mesorectum excision (TME) has become the standard therapy for the treatment of locally advanced rectal cancer (LARC) to reduce the local recurrence rate, however, no…
- Trial name
- NCT03245203
- Testing
- FOLFIRI+beacizumab, CRT
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma
Targeted and Staged Cyber Knife Combined With Interventional Therapy in the Treatment of MHCC
Hepatocellular carcinoma is a highly malignant tumor that is progressing rapidly. Hepatic arterial embolization chemotherapy (TACE) is a common method for the treatment of unresectable of hepatocellular carcinoma.But for patients…
- Trial name
- NCT03243916
- Testing
- TACE plus Cyber knife
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese PLA General Hospital
Melatonin, Myocardial Infarction
Plasma Melatonin AND Mortality After Acute Myocardial Infarction
Pre-clinical and clinical studies have demonstrated that melatonin has cardio-protection effects. Melatonin has anti-inflammatory, antioxidant, antihypertensive, antithrombotic and antilipaemic properties, which plays important…
- Trial name
- NCT03230630
- Testing
- plasma melatonin levels
- Volunteers
- 732 people
- Sponsor
- Chinese PLA General Hospital
Coronary Angiography, Dipeptidyl Peptidase 4
Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients
Increased plasma DPP4 activity (DPP4a) could predict both subclinical and new-onset atherosclerosis, and our previous study has found that the DPP4a was significantly lower in MI patients compared with patients having chest pain…
- Trial name
- NCT03046576
- Testing
- plasma DPP4 activity
- Volunteers
- 625 people
- Sponsor
- Chinese PLA General Hospital
Rheumatoid Arthritis of Knee
The Comparative Study of Intra-articular Injection of Tocilizumab and Compound Betamethasone
Aim: Comparing the efficacy and safety of intra-articular injection of tocilizumab and compound betamethasone. Study design: A randomized, single-blind, parallel controlled and one center trial design. Sample size: 60 cases.
- Trial name
- NCT03215407
- Testing
- Intra-articular Tocilizumab, Intra-articular Compound Betamethasone
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Stroke
Short- and Long-Term Hemodynamic Effects of Carotid Endarterectomy and Carotid Artery Stenting
Carotid artery stenting(CAS) and endarterectomy(CEA) are both important treatment strategy for patients with ICA (internal carotid artery) stenosis.
- Trial name
- NCT03216369
- Testing
- MRI
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma
Recombinant Human Endostatin(Rh-endostatin) Combine With Radiotherapy in the Treatment of Hepatocellular Carcinoma(HCC)
Hepatocellular carcinoma(HCC) is a high malignancy cancer which progress rapidly , and the rates of morbidity and mortality is very high in China.
- Trial name
- NCT03208335
- Testing
- recombinant human endostatin
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Alzheimer Disease
Deep Brain Stimulation for Treatment of Severe Alzheimer's Disease
To investigate the safety of deep brain stimulation in the treatment of severe Alzheimer's disease (AD); to investigate the effectiveness of deep brain stimulation in the treatment of severe AD, i.e., effects of deep brain…
- Trial name
- NCT03115814
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Chinese PLA General Hospital