Clinical trials: sponsored by Chinese PLA General Hospital
B Cell Leukemia, B Cell Lymphoma
A Study Evaluating UCART019 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma
Autologous T cells engineered to express chimeric antigen receptors (CARs) against leukemia antigens such as CD19 on B cells have shown promising results for the treatment of relapsed or refractory B-cell malignancies.
- Trial name
- NCT03166878
- Testing
- UCART019
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Insulin Pump Therapy in Treating Diabetic Nephropathy
Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy
The recent study suggested that oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications.
- Trial name
- NCT03174821
- Testing
- Insulin pump
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Peritoneal Adhesion
Intraperitoneal Chemotherapy Alone or in Combination With Bevacizumab for Ovarian Cancer With Peritoneal Adhesion
Background: Malignant peritoneal adhesion is a common complication and prognostic factor of ovarian cancer and other primary abdominal tumors.
- Trial name
- NCT03095001
- Testing
- Bevacizumab, Carboplatin, paclitaxel
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese PLA General Hospital
Renal Cell Carcinoma
Comparison Between Partial Nephrectomy and Ablation for Renal Tumor
The therapeutic effectiveness of ultrasound guided cooled-probe microwave ablation and laparoscopic partial nephrectomy on T1a renal cell carcinoma is compared to find a better approach for renal tumor.
- Trial name
- NCT03094949
- Testing
- Partial Nephrectomy, microwave ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma, Obesity
Central Obesity and Hepatocellular Carcinoma
Recurrence and metastases after microwave ablation(MWA) of hepatocellular carcinoma(HCC) are the major factors that influence the survival.
- Conditions
- Hepatocellular Carcinoma, Obesity, Microwave Ablation
- Trial name
- NCT03082378
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Lung Neoplasms, Breast Neoplasms
Efficacy Study of Clinical Nutrition to Treat Lung Neoplasms And Breast Carcinoma
This study evaluates the efficacy of clinical nutrition to treat lung neoplasms and breast carcinoma.We estimate there will be 480 patients accepted.120 patients will receive GLSE compound,120 patients will recrive Maitake…
- Trial name
- NCT02603016
- Testing
- GLSE compound, Maitake mushroom extract compound, Ginseng compound
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese PLA General Hospital
Stroke
Assessment and Quantification of Collateral by ASL MRI
Collateral circulation supports brain tissues to maintain blood perfusion in cerebral ischemic stroke and are of great benefit for a better outcome.
- Trial name
- NCT02479243
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Ischemia-reperfusion Injury
Effects of Dexmedetomidine on the Liver Injury After Hepatectomy
To investigate whether dexmedetomidine reduce liver injury after hepatectomy. During hepatectomy, surgeons always took inflow occlusion to reduce blood loss with Pringle maneuver.
- Trial name
- NCT02833688
- Testing
- dexmedetomidine, 0.9% sodium chloride
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese PLA General Hospital
Chronic Pulmonary Aspergillosis
Aspergillus-specific IgG Assays for the Diagnosis of Chronic Pulmonary Aspergillosis (CPA)-Multicenter Study
Aspergillus-specific IgG assays for the diagnosis of chronic pulmonary aspergillosis (CPA)
- Trial name
- NCT03027089
- Where
- China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Cartilage Injury
Effectiveness of Autologous Platelet-rich Plasma on Knee Cartilage Injury
To analyze the effectiveness of intra-articular injection of autologous PRP on knee cartilage repair and evaluating functional recovery of the knee joint in knee cartilage injury patients.
- Trial name
- NCT03024801
- Testing
- autologous platelet-rich plasma, normal saline
- Volunteers
- 50 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer Stage
Comparing the Diagnostic Role of PET/MRI and of PET/CT Among Patients With Gastric Cancer
The results of PET/MRI and PET/CT in each recruited gastric cancer patients will be compared.
- Trial name
- NCT03015298
- Testing
- PET/MRI, PET/CT
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Suboptimal Health Status
Fish Oil and Cardiovascular Suboptimal Health
The purpose of this study is to determine whether omega-3 fatty acids supplementation are effective in the improvement of suboptimal health status and cardiovascular risk.
- Trial name
- NCT02103517
- Testing
- Omega -3 fatty acids
- Where
- 3 sites in China
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Advanced Pancreatic Cancer
Nab-paclitaxel Plus S-1 in Patients With Advanced Pancreatic Cancer
The purpose of this study is to determine the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus S-1 as first-line treatment in Chinese patients with advanced pancreatic ductal adenocarcinoma (PDA).
- Trial name
- NAPSPAC (NCT02124317)
- Testing
- nanoparticle albumin-bound paclitaxel, S-1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Splenic Hilum Lymph Nodes Dissection
3D Versus 2D Laparoscopic Total Gastrectomy With Splenic Hilum Lymph Nodes Dissection
The investigators will perform a prospective randomized comparison between 3D and 2D laparoscopic total gastrectomy with splenic hilum lymph nodes dissection.
- Trial name
- NCT02984787
- Testing
- 3D Laparoscopic total gastrectomy, 2D Laparoscopic total gastrectomy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer
Laparoscopic Versus Open Gastrectomy With Splenic Hilum Lymph Nodes Dissection
Splenic hilum remains challenging during total gastrectomy with D2 lymphadenectomy.The application of minimally invasive surgery for advanced gastric cancer is gaining popularity.
- Trial name
- NCT02980861
- Testing
- Laparoscopic total gastrectomy, Open total gastrectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Neoplasm of Breast
Ultrasound Guided Percutaneous Microwave Ablation for Breast Lesions
The investigators will perform this study to prospectively analyse the clinical outcome after percutaneous microwave ablation(MWA) of benign and malignant breast lesion under ultrasound (US) guidance.
- Trial name
- NCT02860104
- Testing
- microwave ablation
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Lung Neoplasm, Lung Disease
The Value of VOCs Analysis in Exhaled Breath for Pulmonary Benign and Malignant Lesion Diagnosis
The purpose of this study is to analysis the volatile organic gases(VOCs) in exhaled breath of pulmonary lesion patients and healthy controls, in order to find the difference of composition and concentration among groups.
- Trial name
- VOCs (NCT02965300)
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Enthesopathy
Comparation of Ultrasonic Imaging of Enthesopathy in Patients With Psoriatic Arthritis and Psoriasis
Psoriatic arthritis(PsA) and psoriasis(Ps) are two systemic inflammatory diseases linked with rash of psoriasis, but there's still great controversy regarding the exact relationship between them.
- Trial name
- NCT02962271
- Testing
- Musculoskeletal Ultrasound
- Where
- China
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Coronary Heart Disease
Association Study to Evaluate TFPI Gene in CAD in Han Chinese
The cases were hospitalized patients from two medical centers in Beijing and Harbin respectively. Venous blood was collected by standard vein puncture in fasting condition.
- Trial name
- NCT02961127
- Testing
- Venous blood was collected
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Lung Adenocarcinoma Metastatic
A+C in Metastatic Lung Adenocarcinoma Cancer
This is a phase II, prospective, single arm, non comparative study with crizotinib combined with bevacizumab in treatment-naive lung adenocarcinoma cancer patients with ALK translocation or ROS1 translocation or MET amplification
- Trial name
- NCT02946359
- Testing
- Crizotinib, bevacizumab
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital