Clinical trials: sponsored by Chinese PLA General Hospital
Thoracic Lesions
Study on The Value of Endobronchial Ultrasound Elastography in The Diagnosis of Thoracic Lesions
The study aims to evaluate the role of endobronchial ultrasound elastography in differentiated diagnosis of benign and malignant thoracic lesions
- Trial name
- NCT02755506
- Testing
- endobronchial ultrasound elastography
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Osteonecrosis
Mononuclear Cells, Platelets and Zoledronic Acid for Preventing Collapse of the Femoral Head in Osteonecrosis
This study was mainly aimed to evaluate the efficacy of local administration of enriched bone marrow mononuclear cells, platelets and zoledronic acid for the clinical prevention of collapse of the early-stage osteonecrotic…
- Trial name
- NCT02721940
- Testing
- Control group, Mononuclear Cells, Platelets
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Cardio-Renal Syndrome
Adequate Hydration Therapy Combined With Intravenous Infusion of Isosorbide Dinitrate Prevention for CIN
Patients at moderate and high risk for contrast induced nephropathy (CIN) should receive sufficient hydration before application of contrast to prevent CIN, but hydration could obviously increase the preload for congestive heart…
- Trial name
- NCT02718521
- Testing
- Hydration Combined With Intravenous Infusion of Isosorbide Dinitrate, Visipaque, 0.9% sodium chloride fluid administration
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chinese PLA General Hospital
Suboptimal Health Status, Metabolic Abnormality
Application of Monitoring and Intervention Technologies in Suboptimal Health Status
The purpose of this study is to use monitoring and intervention technologies in suboptimal health status in a general population in China and evaluate the effectiveness of these technologies in the improvement of suboptimal…
- Trial name
- NCT02441010
- Testing
- meridian therapy instrument, health information push technology, monitoring device
- Where
- 2 sites in China
- Volunteers
- 2,014 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Lung Neoplasms
Low-frequency Rotating Magnetic System Combined With Systemic Anti-tumor Therapy for Advanced Lung Cancer
The purpose of this study is to determine whether Low-frequency Rotating Magnetic Therapy System is effective and safe in the treatment of advanced lung cancer.
- Trial name
- NCT02701231
- Testing
- Low-frequency Rotating Magnetic Therapy System, Systemic anti-tumor therapy
- Where
- 4 sites in China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Heart Failure
Effects of Glucagon Like Peptide-1 on Haemodynamic Parameters
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that regulates plasma glucose, and GLP-1 analogues were recently introduced for the treatment of acute myocardial infarction.
- Trial name
- NCT02490176
- Testing
- liraglutide
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese PLA General Hospital
MDS, AML
Decitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion for Elderly Patients With Acute Myeloid Leukemia(AML）
Demethylating agent decitabine enhances the immunogenicity of leukemia cells by inducing the expression of cancer testis antigens (CTAs),MHC class I and II molecules,costimulatory molecules and adhesion molecules.
- Trial name
- NCT01690507
- Testing
- Decitabine, Cytarabine, aclacinomycin
- Where
- 2 sites in China
- Volunteers
- 29 people
- Sponsor
- Chinese PLA General Hospital
Difficult to Healing of Skin Ulcers
UC-MSCs Gel Treatment Difficult Healing of Skin Ulcers
This study for a six-month trials, Randomized, open, and parallel comparison before and after its own, Stage test includes screening stage, treatment period and follow-up period.
- Trial name
- UC-MSCs (NCT02685722)
- Testing
- UC-MSCs Gel group, Gel group
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
MSCs
MSCs Source of Sweat Gland Cells of Large Area Skin Injury Patients Transplant of the Wound
The main purpose of this test is to assess the umbilical cord mesenchymal stem cells (MSCs) UC between source sample sweat gland cells wound transplanted effectiveness and safety for the treatment of large area skin lesions of…
- Trial name
- MSCs (NCT02669199)
- Testing
- MSCs
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Wounds
Slow-release Tb4 Collagen and Chitosan Porous Sponge Scaffolds Skin Substitute Treatment is Difficult to Heal Wounds
Evaluation of slow-release Tb4 collagen and chitosan porous sponge scaffolds skin substitutes the effectiveness of clinical trials for the treatment of difficult to heal wounds and security.
- Trial name
- TB4 (NCT02668055)
- Testing
- TB4
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Difficult to Heal Wounds
The Activity of Tissue Engineering Skin Substitutes
The main purpose of this experiment was to evaluate the activity of tissue engineering skin substitutes safety and efficacy studies for the treatment of difficult to heal wounds
- Trial name
- MSCs (NCT02668042)
- Testing
- liveness tissue skin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Sepsis, Severe Sepsis
Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis
In this study, the investigators will dynamically detect the expression of an immune regulator- T cell Ig and mucin domain protein 3 (Tim-3) in patient with sepsis.
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT02180009
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Advanced HER-2 Positive Solid Tumors, Chemotherapy Refactory
Treatment of Chemotherapy Refractory Human Epidermalgrowth Factor Receptor-2( HER-2) Positive Advanced Solid Tumors
RATINALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous T cells may make the body build immune response to kill cancer cells.
- Conditions
- Advanced HER-2 Positive Solid Tumors, Chemotherapy Refactory, HER-2 Antibody Inhibitor Therapy Refactory
- Trial name
- CART-HER-2 (NCT01935843)
- Testing
- CART-HER-2
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese PLA General Hospital
Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma
CD30-directed Chimeric Antigen Receptor T (CART30) Therapy in Relapsed and Refractory CD30 Positive Lymphomas
Chimeric antigen receptor-modified T cells (CART) holds great promise for treatment of tumors. In this trial, CD30 positive Hodgkin's lymphoma and Non-Hodgkin's lymphoma will be treated by CD30-specific CART cells (CART30).
- Trial name
- CART30 (NCT02259556)
- Testing
- CART30
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Multiple Myeloma
Treatment of Chemotherapy Refractory Multiple Myeloma by CART-138
RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells.
- Trial name
- CART-138 (NCT01886976)
- Testing
- CART-138 cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese PLA General Hospital
Breast Cancer, Glioma
Autologous Natural Killer T Cells Infusion for the Treatment of Cancer
The purpose of this study is to assess the safety and effectiveness of natural killer T (NKT) cell-based autologous adoptive immunotherapy in subjects with metastatic, treatment-refractory breast cancer, glioma, hepatocellular…
- Conditions
- Breast Cancer, Glioma, Hepatocellular Cancer, Squamous Cell Lung Cancer
- Trial name
- NCT01801852
- Testing
- NKT cells
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission
Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19
RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells.
- Conditions
- Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission, B-cell Adult Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia
- Trial name
- CART19 (NCT01864889)
- Testing
- anti-CD19-CAR vector-transduced T cells
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Chinese PLA General Hospital
Sepsis, SIRS(Systemic Inflammatory Response Syndrome)
Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients
The imbalance between anti- and pro-inflammation often occurs in patients with sepsis. And continuous such imbalance could lead to immunoparalysis, which is characterized by loss of delayed type hypersensitivity, failure of…
- Trial name
- NCT01801839
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Relapsed Adult Myeloid Leukemia, Chemotherapy Refractory Adult Myeloid Leukemia
Treatment of Relapsed and/or Chemotherapy Refractory CD33 Positive Acute Myeloid Leukemia by CART-33
RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells.
- Trial name
- CART33 (NCT01864902)
- Testing
- CART33 cells, anti-CD33 CART, anti-CD33 CAR T cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Chinese PLA General Hospital
Cardio-Renal Syndrome
Contrast-induced Nephropathy: Incidence,Risk Factors,Effective Prevention and Management Method
This review article have included about ten thousand patients undergoing percutaneous coronary intervention (PCI), aim to identify the incidence of CIN in actual, find some new risk factors and the protecting methods for these…
- Trial name
- NCT02664246
- Testing
- percutaneous coronary intervention
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital