Clinical trials: completed, sponsored by Duke University
Prediabetes, Depressive Symptoms Mild to Moderate in Severity
Mindfulness-based Personalized Health Planning for Reducing Risk of Heart Disease and Diabetes
The purpose of this study is to compare the effectiveness of educational and lifestyle intervention programs aimed at reducing fasting blood sugar and emotional distress in adults with prediabetes.
- Trial name
- AWARENESS (NCT01430221)
- Testing
- Mindfulness-based Personalized Health Planning, Structured & Guided Education
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duke University
Prostate Cancer
Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer
RATIONALE: A diet that is low in fat and/or high in flaxseed may slow or prevent disease progression of prostate cancer. PURPOSE: Randomized phase II trial to study the effectiveness of a diet that is low in fat and/or high in…
- Trial name
- NCT00049309
- Testing
- dietary intervention, flaxseed
- Where
- 3 sites in United States
- Volunteers
- 161 people
- Sponsor
- Duke University
Malnutrition, Prostate Cancer
Diet and Exercise-Based Counseling Program Compared With a Standard Counseling Program in Patients With Early-Stage Prostate Cancer
RATIONALE: An individualized, computer-designed health program may promote changes in diet and physical activity and may improve quality of life in patients who have early-stage prostate cancer.
- Trial name
- NCT00044980
- Testing
- nutritional support, quality-of-life assessment
- Where
- United States
- Sponsor
- Duke University
Breast Cancer, Colorectal Cancer
Exercise and Dietary Counseling in Improving Physical Activity, Nutrition, and Quality of Life in Older Long-Term Cancer Survivors Who Are Overweight
RATIONALE: Exercise and dietary counseling may improve physical activity, nutrition, and quality of life in older long-term cancer survivors who are overweight.
- Conditions
- Breast Cancer, Colorectal Cancer, Prostate Cancer
- Trial name
- NCT00303875
- Testing
- behavioral dietary and exercise intervention
- Where
- 2 sites in United States
- Volunteers
- 641 people
- Sponsor
- Duke University
Obesity, Hypertension
The Mobile Health Platform
This study develops and pilots the initial interface of our mobile health platform that will allow for intra-individual tailoring and personalization of health interventions.
- Conditions
- Obesity, Hypertension, Diabetes
- Trial name
- mHealth (NCT02099513)
- Testing
- The Mobile Health Platform
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Duke University
Breast Cancer, Depression
Study of Health Promotion in Patients With Early-Stage Breast or Prostate Cancer
RATIONALE: Telephone counseling by a nutritionist and a personal trainer may improve physical function and quality of life in patients who have early-stage breast cancer or prostate cancer.
- Conditions
- Breast Cancer, Depression, Fatigue, Malnutrition
- Trial name
- NCT00037024
- Testing
- fatigue assessment and management, nutritional support, physical therapy
- Where
- United States
- Sponsor
- Duke University
Renal Cell Carcinoma
NCCN Renal Cell Registry
This study will consist of three parts: 1) a retrospective chart review of patients treated for mRCC from July 2013 until the start of the educational intervention; 2) an educational program for DCN community oncology providers…
- Trial name
- NCT02677337
- Testing
- chart abstraction, Educational Program
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Duke University
Acute Heart Failure
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)
The primary objective is to test the hypothesis that, compared with placebo, therapy with Subcutaneous (SQ) GLP-1 agonist in the post-Acute Heart Failure Syndrome (AHFS) discharge period will be associated with greater clinical…
- Trial name
- FIGHT (NCT01800968)
- Testing
- Liraglutide
- Where
- 25 sites in United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Post Procedural Constipation
MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery
A. Purpose To compare MiraLAX versus placebo for preventing constipation in the immediate postoperative period following pelvic reconstructive surgery in women taking routine docusate sodium. B. Objectives 1.
- Trial name
- MVP (NCT01691742)
- Testing
- MiraLax, Rescue Laxative
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Duke University
Chronic Lymphocytic Leukemia
A Quality Improvement Approach to the Management of Chronic Lymphocytic Leukemia
This project addresses the need to improve physician knowledge and clinical practice patterns related to quality of life (QoL) concerns for patients with chronic lymphocytic leukemia (CLL).
- Trial name
- Med-IQ CLL (NCT02619604)
- Testing
- Education Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Disease Transmission
Antiseptic Scrub Contamination and Transmission Trial
This study is a prospective, blinded, randomized, controlled trial (RCT) with a crossover design to determine if antiseptic-impregnated surgical scrubs decrease the burden of healthcare providers (HCP) clothing contamination…
- Trial name
- ASCOT (NCT02645214)
- Testing
- Non-antiseptic scrubs, Antiseptic scrubs
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Urinary Tract Infection
Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
This is a study of patients undergoing gynecologic surgery who require post-operative catheterization to determine if prophylactic antibiotic treatment decreases the risk of post-operative urinary tract infection in these…
- Trial name
- STOPP UTI (NCT01450800)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Duke University
Cardiac Surgery, Erythrocyte Transfusion
Impact of Blood Storage Duration on Physiologic Measures
This study is an ancillary (add-on) study to the clinical trial entitled Red Cell Storage Duration Study (RECESS), which has clinicaltrials.gov identifier NCT00991341.
- Trial name
- RECAP (NCT01274390)
- Where
- 4 sites in United States
- Volunteers
- 390 people
- Sponsor
- Duke University
Breast Cancer
DAMES: Daughters And MothErS Against Breast Cancer
Primary Aim: -To explore the feasibility and acceptability of two distinctly different tailored, home-based diet and exercise interventions (one that relies on a partner-assisted, team-based approach that emphasizes the…
- Trial name
- NCT00630591
- Testing
- Standardized Materials Group, Independent Tailored Intervention, Partner-Assisted Tailored Intervention
- Where
- 2 sites in United States
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking
Effects of Smoking Environment on Craving and Smoking
The goal of this study is to evaluate the effects of exposure to standard smoking environments on ability to resist smoking as measured with a Delay to Smoking Task.
- Trial name
- CC2pilot (NCT02416986)
- Testing
- 6 hour smoking abstinence, Delay to Smoking Task (smoking cues), Delay to Smoking Task (nonsmoking cues)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Duke University
Shoulder Dislocation
Efficacy of First Time Anterior Shoulder Decision Tool
This study is a randomized controlled trial using Duke patients to test, compared to the standard of care, a questionnaire and statistical model used to determine how patient preference regarding shoulder pain, physical…
- Trial name
- NCT02656277
- Testing
- Decision Tool, Information on Shoulder Dislocation
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking
Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction
In the present study the investigators will measure the effects of nicotine and non-nicotine factors on brain function during cognitive processes that are differentially sensitive to these factors.
- Trial name
- NNN (NCT01056926)
- Testing
- Quit smoking, Nicotine patch
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking, Healthy
Environments as Smoking Cues: Imaging Brain Substrates, Developing New Treatments (CameraCue)
The overarching goals of this proposal are to 1) identify the network of brain regions specifically activated by personal smoking environment cues and 2) to evaluate the effects of exposure to these cues on smoke…
- Trial name
- NCT01840111
- Testing
- Quit Smoking 6 hours, Quit Smoking 24 hours
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Medication Adherence
A Mobile Phone Based Medication Reminder Program
This study evaluates the feasibility and acceptability of using mobile applications to improve medication adherence. Participants in the experimental group will receive educational materials and daily reminders through mobile…
- Trial name
- NCT02793830
- Testing
- Daily reminders of taking medications, Educational materials
- Volunteers
- 49 people
- Sponsor
- Duke University
Neoplasms
Exercise Intervention for Cancer Survivors
This randomized controlled trial will test a multicomponent intervention to increase exercise Outcome Expectations (OEs) and assess effects of OE changes on exercise intentions and levels of exercise.
- Trial name
- NCT02348710
- Testing
- Exercise OE workbook, Diet workbook
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
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