Clinical trials: sponsored by Ege University
Reversible Pulpitis
The Role of Matrix Metalloproteinases on the Primary Teeth Pulpotomy Treatments
Matrix metalloproteinases (MMPs) are important zinc enzyme group that responsible for reducing extracellular matrix components. It has been reported that MMPs play an important role in pulpal inflammation.
- Trial name
- NCT05145686
- Testing
- Matris metalloproteinase -2, -8, -9 expressions
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ege University
Type 1 Diabetes, Adolescent
Additional Insulin for High Fat/Protein in Type 1 Diabetes
Aim: Dietary carbohydrate is the predominant macronutrient affecting postprandial blood glucose excursions, dietary fat and protein can also significantly impact the postprandial glycemic profile.
- Trial name
- NCT05152121
- Testing
- Carb and fat counting
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ege University
Vascular Access
Comparison of Different Techniques on First Attempt Success in Difficult Vascular Access Patients
The aim of this study is to investigate whether there is any difference between the use of standard techniques, ultrasonography and infra-red light for the success of the first attempt in difficult peripheral vascular access…
- Trial name
- NCT04821362
- Testing
- Ultrasound group, Near Infrared Device Group
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Ege University
Root Canal Infection
One and Two-visit Root Canal Retreatment
A hundred previously root canal treated asymptomatic single-rooted teeth with periapical lesions were treated in single versus multiple visit root canal retreatment.
- Trial name
- NCT05137613
- Testing
- One visit root canal retreatment, Two visit root canal retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Office-based Endometrial Sampling Procedures
Effectiveness of Paracervical Block in Endometrial Sampling Procedures for Pain Control
Office-based endometrial procedures are preferred over diagnostic dilation and curettage, nowadays. Paracervical block is single-shot nerve block that involve a one-time injection of local anesthetic adjacent to the utero-vaginal…
- Trial name
- NCT04572828
- Testing
- Paracervical Block, 550 mg Naproxen Sodium 60 minutes before the procedure, The capped needle
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ege University
Healthy, Exercise
The Effect Of Anaerobic Exercise On Bone Morphogenetic Protein 9
Bone morphogenetic protein (BMP) 9 from the BMP family has an important role in the remodeling of bone and cartilage. Due to these features, BMP9 can play an important role in especially anaerobic exercise training adaptations.
- Trial name
- NCT05117437
- Testing
- Physiological test, Physical test, Biochemical tests
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ege University
Delirium, Pain
The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters
The purpose of this study is to test the effect of a twice daily, 60-minute, nurse initiated, music listening intervention on patients followed in the ICU with MV support as compared to patients who receive care as usual and ear…
- Conditions
- Delirium, Pain, Sedation, Anxiety
- Trial name
- NCT05082623
- Testing
- Music, Earplug
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Ege University
Diabetes Mellitus, Type 2, Exercise
Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
This study aims to determine the effects of a transtheoretical model-based walking exercise training and disease management and metabolic control in patients with type 2 diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Exercise, Walking Pneumonia, Diabetes
- Trial name
- NCT05029804
- Testing
- Education
- Volunteers
- 60 people
- Sponsor
- Ege University
Massage Therapy, Pregnancy Related
The Effects of Whole Body Prenatal Massage Therapy During Pregnancy: A Randomized Controlled Experimental Trial
Background: Massage therapy in many parts of the world is used in all periods of pregnancy. Aim: The study aimed to determine the effect of massage therapy during pregnancy on women and their fetuses in a university hospital in…
- Conditions
- Massage Therapy, Pregnancy Related, Fetus Fetus
- Trial name
- NCT05007210
- Testing
- Prenatal massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Root Canal Infection
One-visit Root Canal Treatment Using Chlorhexidine as a Final Irrigant
A hundred asymptomatic molar teeth with periapical lesions were treated in single versus multiple visit root canal treatment. Half of the teeth were randomly assigned to the one-visit (OV) group and received an additional final…
- Trial name
- NCT05006209
- Testing
- One visit root canal treatment, Two visit root canal treatment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetes Mellitus, Type 2
Learning Modality in Individuals With Diabetes Incompatible
This study was planned to examine the effect of education based on learning styles in diabetic individuals who are incompatible with treatment, on treatment compliance and metabolic goals.
- Trial name
- NCT05007197
- Testing
- The Effect of Diabetes Education Based on Learning Modality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Kidney Transplant; Complications, Cardiac Disease
The Effect of Walking in Kidney Transplant Patients
Cardiovascular diseases are among the most common causes of death in kidney transplant patients. Physical activity is of great importance in preventing cardiovascular diseases after transplantation.
- Trial name
- NCT05003193
- Testing
- pedometer
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ege University
Postoperative Hypothermia, Thermal Comfort
The Effects of Active Warming on Temperature on Core Body and Thermal Comfort
Purpose: This study was conducted to examine the effect of warmed intravenous fluids (WIVF) on the core body temperature and the patients' thermal comforts during the postoperative period in patients undergoing transurethral…
- Conditions
- Postoperative Hypothermia, Thermal Comfort, Body Temperature Changes
- Trial name
- NCT04985617
- Testing
- Warmed Fluids
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ege University
Multiple Sclerosis, Exercise Intervention
Regular Exercise Improves Physical Capacity and Promotes Neurotrophins in Patients With Multiple Sclerosis
ABSTRACT Objective: The investigators aimed to determine the effect of regular exercise on aerobic capacity, strength values, and plasma levels of nerve growth factor (NGF) and Neurotrophin-3 (NT-3) in patients with multiple…
- Conditions
- Multiple Sclerosis, Exercise Intervention, Neuro-Degenerative Disease
- Trial name
- NCT04944251
- Testing
- Regular Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ege University
Breastfeeding, Exclusive, Grandmother
Breastfeeding Counseling Approach Involving Grandmothers (BAKED)
Adequate nutrition during infancy and early childhood are fundamental to the development of a child. It is well recognized that the period from birth to two years of age is a "critical window" for the promotion of optimal growth…
- Trial name
- BAKED (NCT04906122)
- Testing
- The grandmothers in the intervention group will be given breastfeeding counseling before discharge. Home monitoring will be performed in the 2nd week, 3rd and 6th months after the counseling.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Exposure Occupational
Effect of Fıve Different Methods On Smoke
Background: Electrosurgery is used in almost all surgeries. The entire surgical team working in these operating rooms is exposed to surgical smoke.
- Trial name
- SurgicalSmok (NCT04880915)
- Testing
- surgical smoke affects
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Ege University
Osteoarthritis
Application of Injectable Platelet-Rich Fibrin for the Treatment of Temporomandibular Joint Osteoarthritis
The authors designed a randomized, controlled, double-blind clinical trial after the ethical approval by the University Ethics Committee.
- Trial name
- NCT04810923
- Testing
- i-PRF, Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ege University
Stroke Recurrence, Cardiovascular Events
Post-stroke Depression Treatment Effect on Stroke Recurrence
It is not clear whether depresssion can predispose, or precipitate stroke recurrence in patients with stroke. We sought the relationship of post stroke depression with stroke recurrence.
- Conditions
- Stroke Recurrence, Cardiovascular Events, Depression
- Trial name
- STROKE (NCT04776226)
- Testing
- Citalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 1,230 people
- Sponsor
- Ege University
Lymphedema of Upper Limb, Breast Cancer
Evaluation of the Treatment Response in Breast Cancer Related Lymphedema
This study aims to evaluate the effects of the treatment for breast cancer lymphedema. After taking a detailed history and giving a physical examination, breast cancer related lymphedema patients(n:30) will be informed and will…
- Conditions
- Lymphedema of Upper Limb, Breast Cancer, Breast Cancer Lymphedema
- Trial name
- NCT04766489
- Testing
- Complete Decongtestive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ege University
Bone Resorption
Guided Bone Regeneration Using Bovine-derived Xenograft in Combination With or Without Injectable Platelet-rich Fibrin
The aim of the study was to compare the change in augmentation thickness after guided bone regeneration (GBR) using bovine-derived xenograft in combination with or without injectable platelet-rich fibrin (i-PRF).
- Trial name
- NCT04709523
- Testing
- bovine-derived xenograft with i-PRF, bovine-derived xenograft alone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University