Clinical trials: sponsored by Emory University
Sepsis
Comparison of Sepsis Prediction Algorithms
Sepsis is a severe response to infection resulting in organ dysfunction and often leading to death. More than 1.5 million people get sepsis every year in the U.S., and 270,000 Americans die from sepsis annually.
- Trial name
- NCT05943938
- Testing
- Epic Sepsis Model Version - 1, Epic Sepsis Model Version - 2, Emory Sepsis Model
- Where
- 7 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Emory University
Multiple Sclerosis
Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than…
- Trial name
- DIIVA-MS (NCT06495138)
- Testing
- StableEyes
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Emory University
Sickle Cell Disease
Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease
The goal of this study is to evaluate the effects of transauricular vagus and trigeminal nerve stimulation on the treatment of pain in children with Sickle Cell Disease.
- Trial name
- NCT07090668
- Testing
- tAN device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Polybrominated Biphenyl Poisoning
Weight Loss Aid in an Exposed Population
This study will explore whether the use of orlistat results in weight loss that is accompanied by a reduction in the body burdens of polybrominated biphenyls (PBB) and other Persistent Organic Pollutants (POPs).
- Trial name
- NCT03582722
- Testing
- Orlistat, Multivitamin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Malignant Female Reproductive System Neoplasm
An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors
This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such…
- Trial name
- NCT06709534
- Testing
- Exercise Intervention, Functional Assessment, Medical Device Usage and Evaluation
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Emory University
Sickle Cell Disease, Pregnancy Related
Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease
The goal of this study is to determine if there is a positive effect of prophylactic red blood cell (RBC) transfusion of leukoreduced, ABO, Rh (D/Cc/Ee) and Kell matched blood compared to standard of care on the number of…
- Trial name
- ProTIP (NCT06979492)
- Testing
- Prophylactic Transfusion Intervention group: Transfusion, Control group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
End Stage Kidney Disease (ESKD), Hyperglycaemia
Unmasking Diabetes in Dialysis With Continuous Glucose Monitoring
This study will evaluate whether Continuous Glucose Monitoring (CGM) can identify previously unrecognized diabetes and clinically significant hyperglycemia in adults with end-stage kidney disease (ESKD) receiving hemodialysis who…
- Conditions
- End Stage Kidney Disease (ESKD), Hyperglycaemia, Diabetes
- Trial name
- NCT07880795
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Emory University
Osteosarcoma Recurrent, Osteosarcoma in Children
Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma
The goal of this clinical trial is to define the maximum tolerated dose (MTD) and/or Recommended phase 2 dose (RP2D) of Tegavivint in combination with Gemcitabine in patients with relapsed or refractory osteosarcoma (OS).
- Conditions
- Osteosarcoma Recurrent, Osteosarcoma in Children, Relapsed Osteosarcoma, Refractory Osteosarcoma
- Trial name
- NCT07144254
- Testing
- Tegavivint, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Glioma
Tumor Treating Fields for the Treatment of Brainstem Gliomas
This clinical trial tests the safety and side effects of tumor treating fields in treating patients with gliomas located in the brainstem.
- Trial name
- NCT05310448
- Testing
- Optune device
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Mental Health Issue
Weyera Mental Health Pilot Intervention
This study aims to pilot a group-level intervention focused on mental health and resilience among Ethiopian and Eritrean youth. The study follows previous work that showed high rates of mental health outcomes (depression…
- Trial name
- NCT06960187
- Testing
- Weyera Intervention, Delayed intervention (waitlist control)
- Where
- 3 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Emory University
Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8
Vidutolimod (CMP-001) in Combination With Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer
This phase II trial tests whether vidutolimod with nivolumab works to destroy tumor cells in patients with castration resistant prostate cancer that has spread to other places in the body (metastatic).
- Trial name
- NCT05445609
- Testing
- VLP-encapsulated TLR9 Agonist CMP-001,, Nivolumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm
Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases
This early phase I trial evaluates different administration techniques (oral or intravenous) for arginine and tests the safety of giving arginine with whole brain radiation therapy in patients who have cancer that has spread from…
- Trial name
- NCT06328686
- Testing
- Arginine, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Sleep Disturbance, Dementia
Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners
The purpose of this study is to determine if a 6-week videoconference intervention to teach skills to improve sleep is practical, acceptable, and helpful to persons living with memory loss, cognitive impairment, and/or dementia…
- Trial name
- SLEEPMATE (NCT06250725)
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Emory University
Prostate Carcinoma, Stage I Prostate Cancer AJCC v8
CT- Versus MRI-Based Planning for High-Dose-Rate Prostate Brachytherapy for Prostate Cancer
This clinical trial studies the safety of a computed tomography (CT) scan, with or without a magnetic resonance imaging (MRI) scan, in planning for high-dose-rate (HDR) prostate brachytherapy treatment in patients with prostate…
- Conditions
- Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- NCT07859722
- Testing
- Magnetic Resonance Imaging, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
HIV
Mental Health and Medication Adherence Among MSM in South Africa
The goal of this behavioral study is to improve psychological well-being and optimization of HIV prevention and care outcomes for Men who have sex with men (MSM) in South Africa.
- Trial name
- NCT06880172
- Testing
- WeCare
- Where
- South Africa
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
US/PA/E Imaging for Early Identification of Tumor Response in Patients With Stage II-III Triple Negative Breast Cancer Receiving Neoadjuvant Immunotherapy and Chemotherapy
This clinical trial studies how well ultrasound/photoacoustic/elasticity (US/PA/E) imaging works for early identification of tumor response in patients with stage II-III triple-negative breast cancer receiving immunotherapy and…
- Conditions
- Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Triple-Negative Breast Carcinoma
- Trial name
- NCT07862751
- Testing
- Elastography, Magnetic Resonance Imaging, Photoacoustic Imaging
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Metastatic Castration-Resistant Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
Pluvicto for the Treatment of African American Men With Metastatic Castration-Resistant Prostate Cancer
This phase II trial tests how well Pluvicto works in treating African American patients with prostate cancer that has spread from where it first started (primary site) to other places in the body (metastatic) and that has…
- Trial name
- PluvEquity (NCT07860554)
- Testing
- Biopsy Procedure, Biospecimen Collection, Bone Scan
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Emory University
Autism, Autism Spectrum Disorder
Evaluating the Feasibility of Collecting User Interaction Data at the Emory Autism Center Using MapHabit Software
The purpose of this study is to evaluate the impact of the MapHabit System on autistic transition-age youth (ages 18-24) as they navigate key life transitions including graduating from high school, entering adult services…
- Trial name
- NCT07859306
- Testing
- MapHabit System (MHS)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Battered Women, Suicide, Attempted
Effectiveness of Empowerment Group Sessions for Treating Suicidal African American Women in Abusive Relationships
This study will evaluate the effectiveness of culturally competent psychoeducational empowerment sessions in treating suicidal African-American women who are in abusive relationships.
- Trial name
- NCT00601939
- Testing
- Psychoeducational intervention (PEI), Enhanced treatment as usual (ETAU)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Emory University
Anxiety, Anxiety Disorders
Quantifying Multi-step Avoidance in Anxiety
This study aims to learn more about avoidance behavior in people with anxiety, using mathematical models of decision-making processes and decoded neural signals of threat imminence.
- Trial name
- NCT07203027
- Testing
- Behavioral Tasks with imaging
- Where
- 2 sites in United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Emory University
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