Clinical trials: sponsored by Emory University
ART, HIV
Antiretroviral Therapy (ART) Persistence in Different Body Compartments in HIV Negative MSM
The study seeks to understand how anti-HIV drug Biktarvy, which contains the drugs tenofovir alafenamide (TAF), emtricitabine (FTC), and bictegravir (BIC) is absorbed and how long it persists in different body compartments…
- Trial name
- NCT04039217
- Testing
- Biktarvy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Postoperative Atelectasis
GO2 PEEP Study: Bidirectional Oxygenation Valve in Postoperative Atelectasis
This study compares a novel breathing device, called the GO2 Mouthpiece, to the standard breathing tool called the incentive spirometer, thus improving respiratory dynamics of the postoperative patient.
- Trial name
- NCT04253834
- Testing
- Incentive spirometer, GO2 Mouthpiece
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Solid Organ Malignancies, Adenoidcystic Carcinoma
Study of Everolimus (RAD001) in Combination With Lenalidomide
The purpose of this study is to study the combination of two anticancer drugs, everolimus (RAD001) and lenalidomide in patients whose cancer is no longer responding to standard treatment or patients who are unable to tolerate the…
- Conditions
- Solid Organ Malignancies, Adenoidcystic Carcinoma, Neuroendocrine Tumors
- Trial name
- NCT01218555
- Testing
- Lenalidomide, Everolimus
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Emory University
Juvenile Pilocytic Astrocytomas, Optic Pathway Gliomas
Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas
This is a phase II study of the drug, pegylated interferon alfa-2b (PEG-Intron), used to treat brain tumors in a pediatric population.
- Trial name
- NCT02343224
- Testing
- Pegylated interferon alpha-2b
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Alzheimer Disease, Dementia
Testing Tele-Savvy, an On-line Psychoeducation Program for Dementia Family Caregivers
The purpose of this study is to test the psychoeducational program "Tele-Savvy." Tele-Savvy is an internet based, group education program developed from an in person program called Savvy Caregiver.
- Trial name
- NCT03033875
- Testing
- Tele-Savvy, Healthy Living Education Program
- Where
- United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Emory University
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression
Dynamics of Inflammation and Its Blockade on Motivational Circuitry in Depression
The main purpose of this study is to examine the effects of infliximab on measures related to depression symptoms. Infliximab is also known by its brand name Remicade.
- Trial name
- NCT03006393
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Emory University
Type 2 Diabetes
Liraglutide Hospital Discharge Trial
High blood glucose levels in hospitalized patients with diabetes are associated with increased risk of medical complications and death.
- Trial name
- NCT01919489
- Testing
- Liraglutide + OADs, Glargine + OADs
- Where
- 5 sites in United States
- Volunteers
- 273 people
- Sponsor
- Emory University
Sinus Problem
Safety and Effectiveness of the Peregrine Drivable ENT Scope for Endoscopy of the Paranasal Sinuses
The purpose of this study is to assess the safety and effectiveness of the Peregrine endoscope in patients in the office setting in terms of access into and visualization of the paranasal sinus anatomy, image quality, patient…
- Trial name
- NCT04096482
- Testing
- Peregrine Drivable ENT Scope, Standard 30° 4mm Endoscope
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Sexual Violence
Preventing Sexual Violence in College Men: RealConsent for Use in Vietnam
This study is a randomized controlled trial using a web-based adaptation of the RealConsent program among eligible college men in Hanoi, Vietnam.
- Trial name
- NCT04147455
- Testing
- Adapted RealConsent, Health Education Control Condition
- Where
- 2 sites in Vietnam
- Volunteers
- 793 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 1 Diabetes
A Study of Rapid-Acting Mealtime Insulin in Children and Adolescents With Newly Diagnosed Type 1 Diabetes Mellitus
Type 1 diabetes mellitus (T1DM) is a challenging medical disorder, especially in children and adolescents. In order to prevent the chronic complications of hyperglycemia, the maintenance of near-normal glycemic control must be…
- Trial name
- NCT04157738
- Testing
- Rapid-Acting Insulin, Long acting insulin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Cancer, Pain
Intranasal (NAS) Ketamine for Cancer Pain
The main purpose of this study is to determine the safety, feasibility, and utility of intranasal (NAS) ketamine in persistent uncontrolled cancer related pain.
- Trial name
- NCT03146806
- Testing
- Intranasal ketamine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Voice Disorder, Vocal Cord Atrophy
Expiratory Muscle Strength Training and Phonation Resistance Training Exercises For Elderly Patients With Vocal Fold Atrophy
The larynx and vocal folds undergo many age-related changes in their physiology and structure that can lead to undesirable effects on the voice, with changes in the respiratory system compounding these deficits.
- Conditions
- Voice Disorder, Vocal Cord Atrophy, Presbyphonia
- Trial name
- NCT03696576
- Testing
- EMST, PhoRTE
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
HIV/AIDS
Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens
This study is being conducted to determine if the uptake of anti-HIV medication, called Genvoya®, at different time-frames, is different at several body sites, including mucosal tissues.
- Trial name
- NCT03976752
- Testing
- Genvoya
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Emory University
Diabetes
Dexcom G6 Observational Study
This is an exploratory prospective study primary aiming to evaluate differences between Point-of-care (POC) testing (standard of care) and Dexcom G6 CGM (Continues Glucose Monitoring sensor system) in 1) glycemic control measured…
- Trial name
- NCT03832907
- Testing
- Dexcom G6 CGM - Continues Glucose Monitoring sensor system, POC BG - Point-of-Care Blood Glucose monitoring
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Emory University
Sickle Cell Disease
Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
Chronic Pain is associated with morbidity and poor quality of life in patients with Sickle Cell Disease (SCD). Complementary therapies, such as yoga are beneficial in patients with non-SCD chronic pain conditions.
- Trial name
- NCT03694548
- Testing
- Part A Survey, Part B Yoga Program
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Otolaryngeal Cancer
Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients
The goal of this prospective randomized double blinded placebo controlled study is to investigate if a single dose of ketamine in addition to standard anesthesia will reduce the risk of delirium in otolaryngeal cancer patients…
- Trial name
- NCT03040024
- Testing
- Ketamine, Electroencephalogram (EEG)
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Emory University
Neoplasm Metastasis
Whole Brain Radiation Therapy With Boost to Metastatic Tumor Volume Using RapidArc
Brain metastases are the most common adult intracranial tumor, occurring in approximately 10% to 30% of adult cancer patients, and represent an important cause of morbidity and mortality.
- Trial name
- NCT01218542
- Testing
- Volumetric modulated arc therapy
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Recurrent Small Cell Lung Carcinoma
Tremelimumab and Durvalumab With or Without Radiation Therapy in Patients With Relapsed Small Cell Lung Cancer
This randomized clinical trial studies how well tremelimumab and durvalumab with or without radiation therapy works in treating patients with small cell lung cancer that has returned after a period of improvement.
- Trial name
- NCT02701400
- Testing
- Durvalumab, Hypofractionated Radiation Therapy, Stereotactic Body Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Emory University
PostTraumatic Stress Disorder
Closed Loop Vagal Nerve Stimulation for Patients With Posttraumatic Stress Disorder
The tasks of the project are to map the potency and kinetics of the neurologic, autonomic peripheral, inflammatory, and behavioral responses to vagal nerve stimulation (VNS) vs.
- Trial name
- NCT02992899
- Testing
- GammaCore/electroCore non-invasive VNS device, O-15 water
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Emory University