Clinical trials: completed, sponsored by Emory University
Lung Cancer, Cancer of Lung
Study of Arsenic Trioxide in Small Cell Lung Cancer
The purpose of this study is to study the effect of an anticancer drug, Arsenic Trioxide, in patients with small cell lung cancer who have failed at least one standard chemotherapy regimen as well as patients who are unable to…
- Conditions
- Lung Cancer, Cancer of Lung, Pulmonary Cancer, Pulmonary Neoplasms
- Trial name
- NCT01470248
- Testing
- Arsenic Trioxide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Heart Failure
Exercise and Cognitive Retraining to Improve Cognition in Heart Failure.
Cognitive impairment (CI) is a prevalent problem in persons with HF heart failure (HF) and is associated with adverse clinical outcomes, higher mortality and poorer quality of life.
- Trial name
- EXCITE (NCT02151266)
- Testing
- Exercise and Cognitive retraining, Exercise Only, Stretching and Flexibility
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Emory University
Cancer
Validation of FACBC for Detection of Metastasis Among High-risk Prostate Cancer Patients With Presumed Localized Disease
This study is for patients who have a high risk of metastatic prostate cancer (cancer that has spread outside of the prostate) who are going to have radical prostatectomy.
- Trial name
- EDRN-FACBC (NCT03081884)
- Testing
- FACBC PET-CT Imaging
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Emory University
Diabetes
A Randomized Study to Evaluate the Efficacy of Insulclock® in Patients With Uncontrolled Type 2 Diabetes
Poor adherence to insulin regimens is reported in up to two-third of patients with diabetes; thus it is important to identify patients at risk and to develop strategies and tools to increase adherence to prescribed insulin…
- Trial name
- NCT03224234
- Testing
- Insulclock with feedback, Insulclock without feedback
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Emory University
Morquio Disease, MPS - Mucopolysaccharidosis
Pregnancy With Morquio Syndrome - What Are Patients' Perspectives and Has ERT Changed Them?
The present study seeks to interview women with Morquio A and Morquio B syndrome, to explore their concerns surrounding pregnancy and the impact of ERT on their perspectives, in comparison with the control group of Morquio B…
- Trial name
- MorqPreg (NCT03150069)
- Testing
- Interview
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder, Moderate Language Delay
Direct Instruction Language for Learning in Autism Spectrum Disorder
The purpose of this study is to test whether Direct Instruction - Language for Learning (DI-LL) is an effective way to teach language skills to children with autism spectrum disorder (ASD) and moderate language delay.
- Trial name
- DILLASD (NCT02483910)
- Testing
- Direct Instruction-Language for Learning (DI-LL) via telehealth (e.g., Zoom or WebEx), Standard of care delivered via telehealth (e.g., Zoom or WebEx)
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Emory University
Complications of Transplanted Organs and Tissue
Identification and Treatment of Diabetes In Solid Organ Transplant Recipients
The purpose of this study is to determine the influence of post-transplant diabetes on medical and psychosocial outcomes in individuals who receive solid-organ transplant prior to 18 years of age and their families.
- Trial name
- NCT02605200
- Testing
- Psychologist Support, Pediatric Certified Diabetes Educators (CDEs) Support
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Emory University
Autism Spectrum Disorder, Obesity
Open Trial Obesity CHANGE Program ASD
The purpose of this study is to determine if a program can help children with autism who are overweight. Specifically, this study will look to see if changes in a child's eating habits and exercise can help with weight loss.
- Trial name
- NCT03047018
- Testing
- The Changing Health in Autism through Nutrition, Getting fit and Expanding variety (CHANGE) Program
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Vaccination, Skin Absorption
Microneedle Patch Study in Healthy Infants/Young Children
Microneedles can be prepared as a low-cost patch that is simple for patients to apply for vaccine delivery targeting the many antigen-presenting cells present in the skin.
- Trial name
- NCT03207763
- Testing
- Microneedle Formulation 1, Microneedle Formulation 2
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression
The ISLAND Study: InSuLa Assessed Needs for Depression
While there are many effective options for treating a major depressive episode, there are no clinical markers that predict the likelihood of remission with an initial trial of either an antidepressant medication or psychotherapy.
- Trial name
- ISLAND (NCT02137369)
- Testing
- Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Combination treatment (SSRI + CBT)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Emory University
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Pain
Use of On-Q Pump for Pain Post C-Section
The main purpose of this study is to examine if pain levels treated with intrathecal (IT) preservative-free morphine (PFM) after a cesarean section improve with the additional use of continuous subfascial wound infiltration with…
- Trial name
- NCT02579629
- Testing
- Ropivacaine 0.1%, Ropivacaine 0.2%, Normal saline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Kidney Transplantation
Bela 8 Week Dosing
The purpose of this study is to transition patients who have been stable on Belatacept for one year after kidney transplant from standard 4-week to an investigational 8-week belatacept dosing schedule.
- Trial name
- NCT02560558
- Testing
- Belatacept
- Where
- 2 sites in United States
- Volunteers
- 166 people
- Sponsor
- Emory University
Positive-Pressure Respiration, Communication
Determining the Benefits of Improving Communication in BPAP/CPAP Users
The purpose of this study is to determine the effectiveness of a non-invasive communication aid for BPAP/CPAP masks. This study also looks to determine the potential impact of the device on patients with obstructive sleep apnea…
- Trial name
- NCT03795753
- Testing
- F2S Communicator, Non-functioning Communicator
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Emory University
Cardiovascular Disease, Coronary Artery Disease
Mental Stress Ischemia: Biofeedback Study
The purpose of this study is to evaluate the blood flow to the heart during stress and assess changes in blood flow after psychological treatment in participants with coronary artery disease.
- Trial name
- MIBS (NCT02657382)
- Testing
- Heart Rate Variability (HRV) Biofeedback (BF), Mental Stress Protocol
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Hip Arthrosis, Osteoarthritis
Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total Hip Arthroplasty
In this prospective, randomized study, investigators will look at the outcome of total hip arthroplasty through the anterior approach in regard to the surgical treatment of the anterior hip capsule.
- Conditions
- Hip Arthrosis, Osteoarthritis, Arthritis
- Trial name
- NCT02121964
- Testing
- Capsulectomy in Direct Anterior Total Hip Arthroplasty, Capsulotomy in Direct Anterior Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Emory University
HIV Infections
Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis.
This study is being conducted to determine if the uptake of anti-HIV medications called Genvoya® and darunavir is different at several body sites, including mucosal tissues.
- Trial name
- PEP2 (NCT03472963)
- Testing
- Single dose of Genvoya® and a single 800 mg dose of Darunavir®
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Vaccination
P3+ Intervention Phase
This study will address vaccine uptake both for pregnant women and for their children, through 20 months of age, to test the hypothesis that exposure to the P3+ intervention package will increase the likelihood a pregnant woman…
- Trial name
- NCT02898688
- Testing
- Control Site, Intervention Site, Patient-level Control Group
- Where
- 23 sites in United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Emory University